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A Dynamic Switch in the Replication Timing of Key Regulator Genes in Embryonic Stem Cells upon Neural Induction

Pages 1619-1624 | Published online: 05 Nov 2004

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Articles from other publishers (72)

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Cathia Rausch, Patrick Weber, Paulina Prorok, David Hörl, Andreas Maiser, Anne Lehmkuhl, Vadim O Chagin, Corella S Casas-Delucchi, Heinrich Leonhardt & M Cristina Cardoso. (2020) Developmental differences in genome replication program and origin activation. Nucleic Acids Research 48:22, pages 12751-12777.
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Vishnu Dileep, Korey A. Wilson, Claire Marchal, Xiaowen Lyu, Peiyao A. Zhao, Ben Li, Axel Poulet, Daniel A. Bartlett, Juan Carlos Rivera-Mulia, Zhaohui S. Qin, Allan J. Robins, Thomas C. Schulz, Michael J. Kulik, Rachel Patton McCord, Job Dekker, Stephen Dalton, Victor G. Corces & David M. Gilbert. (2019) Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment. Stem Cell Reports 13:1, pages 193-206.
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Ichiro Hiratani & Saori Takahashi. (2019) DNA Replication Timing Enters the Single-Cell Era. Genes 10:3, pages 221.
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Peiyao A. Zhao, Juan Carlos Rivera-Mulia & David M. Gilbert. 2017. DNA Replication. DNA Replication 229 257 .
José Luis Ordóñez, Daniel Osuna, Juan Madoz-Gúrpide & Enrique de Álava. 2017. The Molecular Basis of Human Cancer. The Molecular Basis of Human Cancer 623 655 .
Sarah Elizabeth Hemming, Dimitrios Cakouros & Stan Gronthos. 2016. The Biology and Therapeutic Application of Mesenchymal Cells. The Biology and Therapeutic Application of Mesenchymal Cells 39 57 .
Lo Sardo Federica. 2016. Polycomb Group Proteins. Polycomb Group Proteins 55 65 .
Wei FengScott D. Michaels. (2015) Accessing the Inaccessible: The Organization, Transcription, Replication, and Repair of Heterochromatin in Plants. Annual Review of Genetics 49:1, pages 439-459.
Crossref
Vladimir V. Sherstyuk, Alexander I. Shevchenko & Suren M. Zakian. (2013) Epigenetic landscape for initiation of DNA replication. Chromosoma 123:3, pages 183-199.
Crossref
Wei‐Hui Liu, Li‐Na Ren, Tao Chen, Nan You, Li‐Ye Liu, Tao Wang, Hong‐Tao Yan, Hao Luo & Li‐Jun Tang. (2013) Unbalanced distribution of materials: the art of giving rise to hepatocytes from liver stem/progenitor cells. Journal of Cellular and Molecular Medicine 18:1, pages 1-14.
Crossref
Jason Fan & Dieter Egli. 2014. Principles of Cloning. Principles of Cloning 393 406 .
Hyung-yul Lee, Dan Wei & Mary R. Loeken. (2014) Lack of metformin effect on mouse embryo AMPK activity: implications for metformin treatment during pregnancy. Diabetes/Metabolism Research and Reviews 30:1, pages 23-30.
Crossref
Jin Hyuk Jung, Xiao Dan Wang & Mary R. Loeken. (2013) Mouse Embryonic Stem Cells Established in Physiological-Glucose Media Express the High K M Glut2 Glucose Transporter Expressed by Normal Embryos . Stem Cells Translational Medicine 2:12, pages 929-934.
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Benjamin D. Pope & David M. Gilbert. (2013) The Replication Domain Model: Regulating Replicon Firing in the Context of Large-Scale Chromosome Architecture. Journal of Molecular Biology 425:23, pages 4690-4695.
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Jie Zhang, Li Li, Luying Peng, Yingxian Sun & Jue Li. (2013) An Efficient Weighted Graph Strategy to Identify Differentiation Associated Genes in Embryonic Stem Cells. PLoS ONE 8:4, pages e62716.
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Apurva V. ShirodkarRosanne St. BernardAnna GavryushovaAnna KopBritta J. KnightMatthew Shu-Ching YanHon-Sum Jeffrey ManManeesh SudRobert P. Hebbel, Peter Oettgen, William C. Aird & Philip A. Marsden. (2013) A mechanistic role for DNA methylation in endothelial cell (EC)-enriched gene expression: relationship with DNA replication timing. Blood 121:17, pages 3531-3540.
Crossref
Federica Lo Sardo, Chiara Lanzuolo, Federico Comoglio, Marco De Bardi, Renato Paro & Valerio Orlando. (2013) PcG-Mediated Higher-Order Chromatin Structures Modulate Replication Programs at the Drosophila BX-C. PLoS Genetics 9:2, pages e1003283.
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Benjamin D. Pope, Tamir Chandra, Quinton Buckley, Matthew Hoare, Tyrone Ryba, Frances K. Wiseman, Anna Kuta, Michael D. Wilson, Duncan T. Odom & David M. Gilbert. (2012) Replication-timing boundaries facilitate cell-type and species-specific regulation of a rearranged human chromosome in mouse. Human Molecular Genetics 21:19, pages 4162-4170.
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Y. Wu, M. Viana, S. Thirumangalathu & M. R. Loeken. (2011) AMP-activated protein kinase mediates effects of oxidative stress on embryo gene expression in a mouse model of diabetic embryopathy. Diabetologia 55:1, pages 245-254.
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Xiao Dan Wang, Sarah C. Morgan & Mary R. Loeken. (2011) Pax3 Stimulates p53 Ubiquitination and Degradation Independent of Transcription. PLoS ONE 6:12, pages e29379.
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Luca Mazzarella, Helle F. Jørgensen, Jorge Soza-Ried, Anna V. Terry, Stella Pearson, Georges Lacaud, Valerie Kouskoff, Matthias Merkenschlager & Amanda G. Fisher. (2011) Embryonic stem cell–derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression. Blood 117:1, pages 83-87.
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Sarah Snykers, Joery De Kock, Vanhaecke Tamara & Vera Rogiers. 2011. Mesenchymal Stem Cell Assays and Applications. Mesenchymal Stem Cell Assays and Applications 305 314 .
Julie A. LessardGerald R. Crabtree. (2010) Chromatin Regulatory Mechanisms in Pluripotency. Annual Review of Cell and Developmental Biology 26:1, pages 503-532.
Crossref
Yusuke Hirabayashi & Yukiko Gotoh. (2010) Epigenetic control of neural precursor cell fate during development. Nature Reviews Neuroscience 11:6, pages 377-388.
Crossref
S. K. Munro, C. M. Farquhar, M. D. Mitchell & A. P. Ponnampalam. (2010) Epigenetic regulation of endometrium during the menstrual cycle. Molecular Human Reproduction 16:5, pages 297-310.
Crossref
Yoel Shufaro, Orly Lacham-Kaplan, Ben-Zion Tzuberi, John McLaughlin, Alan Trounson, Howard Cedar & Benjamin E. Reubinoff. (2010) Reprogramming of DNA Replication Timing. Stem Cells 28:3, pages 443-449.
Crossref
Naiara Z Saraiva. (2010) Histone acetylation and its role in embryonic stem cell differentiation. World Journal of Stem Cells 2:6, pages 121.
Crossref
Angel Alvarez, Monowar Hossain, Elise Dantuma, Stephanie Merchant & Kiminobu Sugaya. (2010) Nanog overexpression allows human mesenchymal stem cells to differentiate into neural cells——Nanog transdifferentiates mesenchymal stem cells. Neuroscience and Medicine 01:01, pages 1-13.
Crossref
Carla Sawan & Zdenko Herceg. 2010. Epigenetics and Cancer, Part A. Epigenetics and Cancer, Part A 57 85 .
Benjamin D. Pope, Ichiro Hiratani & David M. Gilbert. (2009) Domain-wide regulation of DNA replication timing during mammalian development. Chromosome Research 18:1, pages 127-136.
Crossref
Ichiro Hiratani & David M. Gilbert. 2010. The Cell Biology of Stem Cells. The Cell Biology of Stem Cells 41 58 .
Kelly J. Morris, Mita Chotalia & Ana Pombo. 2010. The Cell Biology of Stem Cells. The Cell Biology of Stem Cells 14 25 .
Tomoki Yokochi, Kristina Poduch, Tyrone Ryba, Junjie Lu, Ichiro Hiratani, Makoto Tachibana, Yoichi Shinkai & David M. Gilbert. (2009) G9a selectively represses a class of late-replicating genes at the nuclear periphery. Proceedings of the National Academy of Sciences 106:46, pages 19363-19368.
Crossref
Maarten HoogenkampMonika LichtingerHanna KrysinskaChristophe Lancrin, Deborah ClarkeAndrew WilliamsonLuca MazzarellaRichard IngramHelle JorgensenAmanda FisherDaniel G. Tenen, Valerie KouskoffGeorges Lacaud & Constanze Bonifer. (2009) Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program. Blood 114:2, pages 299-309.
Crossref
Sarah Snykers, Tom Henkens, Evelien De Rop, Mathieu Vinken, Joanna Fraczek, Joery De Kock, Evi De Prins, Albert Geerts, Vera Rogiers & Tamara Vanhaecke. (2009) Role of epigenetics in liver-specific gene transcription, hepatocyte differentiation and stem cell reprogrammation. Journal of Hepatology 51:1, pages 187-211.
Crossref
Laura Lande-Diner, Jianmin Zhang & Howard Cedar. (2009) Shifts in Replication Timing Actively Affect Histone Acetylation during Nucleosome Reassembly. Molecular Cell 34:6, pages 767-774.
Crossref
Susanne M. Kooistra, Rajkumar P. Thummer & Bart J.L. Eggen. (2009) Characterization of human UTF1, a chromatin-associated protein with repressor activity expressed in pluripotent cells. Stem Cell Research 2:3, pages 211-218.
Crossref
Anita Göndör & Rolf Ohlsson. (2009) Replication timing and epigenetic reprogramming of gene expression: a two-way relationship?. Nature Reviews Genetics 10:4, pages 269-276.
Crossref
Ichiro Hiratani, Shin-ichiro Takebayashi, Junjie Lu & David M Gilbert. (2009) Replication timing and transcriptional control: beyond cause and effect—part II. Current Opinion in Genetics & Development 19:2, pages 142-149.
Crossref
Michaela Schwaiger, Michael B. Stadler, Oliver Bell, Hubertus Kohler, Edward J. Oakeley & Dirk Schübeler. (2009) Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome . Genes & Development 23:5, pages 589-601.
Crossref
Shlomit Farkash-Amar, Doron Lipson, Andreas Polten, Alon Goren, Charles Helmstetter, Zohar Yakhini & Itamar Simon. (2008) Global organization of replication time zones of the mouse genome. Genome Research 18:10, pages 1562-1570.
Crossref
B.V. Johnson, N. Shindo, P.D. Rathjen, J. Rathjen & R.A. Keough. (2008) Understanding pluripotency--how embryonic stem cells keep their options open. Molecular Human Reproduction 14:9, pages 513-520.
Crossref
G Zardo, G Cimino & C Nervi. (2008) Epigenetic plasticity of chromatin in embryonic and hematopoietic stem/progenitor cells: therapeutic potential of cell reprogramming. Leukemia 22:8, pages 1503-1518.
Crossref
Vivek Shukla, Thomas Vaissière & Zdenko Herceg. (2008) Histone acetylation and chromatin signature in stem cell identity and cancer. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 637:1-2, pages 1-15.
Crossref
Robert Schneider & Rudolf Grosschedl. (2007) Dynamics and interplay of nuclear architecture, genome organization, and gene expression. Genes & Development 21:23, pages 3027-3043.
Crossref
R Murr, T Vaissière, C Sawan, V Shukla & Z Herceg. (2007) Orchestration of chromatin-based processes: mind the TRRAP. Oncogene 26:37, pages 5358-5372.
Crossref
Mirit I. Aladjem. (2007) Replication in context: dynamic regulation of DNA replication patterns in metazoans. Nature Reviews Genetics 8:8, pages 588-600.
Crossref
Neerja Karnani, Christopher Taylor, Ankit Malhotra & Anindya Dutta. (2007) Pan-S replication patterns and chromosomal domains defined by genome-tiling arrays of ENCODE genomic areas. Genome Research 17:6, pages 865-876.
Crossref
Laura Lande-Diner, Jianmin Zhang, Ittai Ben-Porath, Ninette Amariglio, Ilana Keshet, Merav Hecht, Veronique Azuara, Amanda G. Fisher, Gideon Rechavi & Howard Cedar. (2007) Role of DNA Methylation in Stable Gene Repression. Journal of Biological Chemistry 282:16, pages 12194-12200.
Crossref
Mikhail Spivakov & Amanda G. Fisher. (2007) Epigenetic signatures of stem-cell identity. Nature Reviews Genetics 8:4, pages 263-271.
Crossref
Sara Giadrossi, Maria Dvorkina & Amanda G Fisher. (2007) Chromatin organization and differentiation in embryonic stem cell models. Current Opinion in Genetics & Development 17:2, pages 132-138.
Crossref
Henrietta Szutorisz, Andrew Georgiou, László Tora & Niall Dillon. (2006) The Proteasome Restricts Permissive Transcription at Tissue-Specific Gene Loci in Embryonic Stem Cells. Cell 127:7, pages 1375-1388.
Crossref
Mercedes Montero-Balaguer, Michael R. Lang, Sherri Weiss Sachdev, Christiane Knappmeyer, Rodney A. Stewart, Ana De La Guardia, Antonis K. Hatzopoulos & Ela W. Knapik. (2006) The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish . Developmental Dynamics 235:12, pages 3199-3212.
Crossref
Véronique Azuara. (2006) Profiling of DNA replication timing in unsynchronized cell populations. Nature Protocols 1:4, pages 2171-2177.
Crossref
Laurie A Boyer, Divya Mathur & Rudolf Jaenisch. (2006) Molecular control of pluripotency. Current Opinion in Genetics & Development 16:5, pages 455-462.
Crossref
Paolo Norio. (2006) DNA replication: the unbearable lightness of origins. EMBO reports 7:8, pages 779-781.
Crossref
Daniele Zink. (2006) The temporal program of DNA replication: new insights into old questions. Chromosoma 115:4, pages 273-287.
Crossref
Eran Meshorer & Tom Misteli. (2006) Chromatin in pluripotent embryonic stem cells and differentiation. Nature Reviews Molecular Cell Biology 7:7, pages 540-546.
Crossref
Laura P O'Neill, Matthew D VerMilyea & Bryan M Turner. (2006) Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations. Nature Genetics 38:7, pages 835-841.
Crossref
Véronique Azuara, Pascale Perry, Stephan Sauer, Mikhail Spivakov, Helle F. Jørgensen, Rosalind M. John, Mina Gouti, Miguel Casanova, Gary Warnes, Matthias Merkenschlager & Amanda G. Fisher. (2006) Chromatin signatures of pluripotent cell lines. Nature Cell Biology 8:5, pages 532-538.
Crossref
Carl L Schildkraut & Zeqiang Guan. (2006) Replicators lessen transcriptional silencing. Nature Biotechnology 24:5, pages 523-524.
Crossref
Michaela Schwaiger & Dirk Schübeler. (2006) A question of timing: emerging links between transcription and replication. Current Opinion in Genetics & Development 16:2, pages 177-183.
Crossref
Bradley E. Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie, Michael Kamal, Dana J. Huebert, James Cuff, Ben Fry, Alex Meissner, Marius Wernig, Kathrin Plath, Rudolf Jaenisch, Alexandre Wagschal, Robert Feil, Stuart L. Schreiber & Eric S. Lander. (2006) A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells. Cell 125:2, pages 315-326.
Crossref
Ruth R. E. Williams, Véronique Azuara, Pascale Perry, Stephan Sauer, Maria Dvorkina, Helle Jørgensen, Jeffery Roix, Philip McQueen, Tom Misteli, Matthias Merkenschlager & Amanda G. Fisher. (2006) Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus . Journal of Cell Science 119:1, pages 132-140.
Crossref
David M. Gilbert. (2005) Origins Go Plastic. Molecular Cell 20:5, pages 657-658.
Crossref
Henrietta Szutorisz & Niall Dillon. (2005) The epigenetic basis for embryonic stem cell pluripotency. BioEssays 27:12, pages 1286-1293.
Crossref
Paolo Norio, Settapong Kosiyatrakul, Qiaoxin Yang, Zeqiang Guan, Nicholas M. Brown, Sharon Thomas, Roy Riblet & Carl L. Schildkraut. (2005) Progressive Activation of DNA Replication Initiation in Large Domains of the Immunoglobulin Heavy Chain Locus during B Cell Development. Molecular Cell 20:4, pages 575-587.
Crossref
Lyubomira Chakalova, Emmanuel Debrand, Jennifer A. Mitchell, Cameron S. Osborne & Peter Fraser. (2005) Replication and transcription: Shaping the landscape of the genome. Nature Reviews Genetics 6:9, pages 669-677.
Crossref

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