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Jean-Luc Evrard, Laurent Pieuchot, Jan W. Vos, Isabelle Vernos & Anne-Catherine Schmit. (2009) Plant TPX2 and related proteins. Plant Signaling & Behavior 4:1, pages 69-72.
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Tomomi M. Yamamoto, Andrea L. Lewellyn & James L. Maller. (2008) Regulation of the Aurora B Chromosome Passenger Protein Complex during Oocyte Maturation in Xenopus laevis. Molecular and Cellular Biology 28:12, pages 4196-4203.
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Articles from other publishers (42)
Dalila Boi, Elisabetta Rubini, Sara Breccia, Giulia Guarguaglini & Alessandro Paiardini. (2023) When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases. International Journal of Molecular Sciences 24:5, pages 4746.
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Ting Shao, Xiling Jiang, Guochang Bao, Chunsheng Li & Changgang Guo. (2022) Comprehensive Analysis of the Oncogenic Role of Targeting Protein for Xklp2 (TPX2) in Human Malignancies. Disease Markers 2022, pages 1-13.
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Lauren J. TomlinsonMatthew Batchelor, Joscelyn SarsbyDominic P. ByrnePhilip J. BrownridgeRichard Bayliss, Patrick A. Eyers & Claire E. Eyers. (2022) Exploring the Conformational Landscape and Stability of Aurora A Using Ion-Mobility Mass Spectrometry and Molecular Modeling. Journal of the American Society for Mass Spectrometry 33:3, pages 420-435.
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Kaksha Sankhe, Arati Prabhu & Tabassum Khan. (2021) Design strategies, SAR, and mechanistic insight of Aurora kinase inhibitors in cancer. Chemical Biology & Drug Design 98:1, pages 73-93.
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N. Tavernier, Y. Thomas, S. Vigneron, P. Maisonneuve, S. Orlicky, P. Mader, S. G. Regmi, L. Van Hove, N. M. Levinson, G. Gasmi-Seabrook, N. Joly, M. Poteau, G. Velez-Aguilera, O. Gavet, A. Castro, M. Dasso, T. Lorca, F. Sicheri & L. Pintard. (2021) Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry. Nature Communications 12:1.
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Yugo Tsuchiya, Dominic P. Byrne, Selena G. Burgess, Jenny Bormann, Jovana Baković, Yueyang Huang, Alexander Zhyvoloup, Bess Yi Kun Yu, Sew Peak-Chew, Trang Tran, Fiona Bellany, Alethea B. Tabor, AW Edith Chan, Lalitha Guruprasad, Oleg Garifulin, Valeriy Filonenko, Matthias Vonderach, Samantha Ferries, Claire E. Eyers, John Carroll, Mark Skehel, Richard Bayliss, Patrick A. Eyers & Ivan Gout. (2020) Covalent Aurora A regulation by the metabolic integrator coenzyme A. Redox Biology 28, pages 101318.
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Valéria Barbosa de Souza & Daniel Fábio Kawano. (2020) Structural basis for the design of allosteric inhibitors of the Aurora kinase A enzyme in the cancer chemotherapy. Biochimica et Biophysica Acta (BBA) - General Subjects 1864:1, pages 129448.
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Zhenhong Zou, Bingbing Zheng, Jiaxi Li, Xiaorui Lv, Han Zhang, Fanqi Yu, Lingdong Kong, Yimin Li, Mengqi Yu, Lu Fang & Bo Liang. (2018) TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT. Biomedicine & Pharmacotherapy 107, pages 1286-1293.
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Yuan Tian, Lian‐Lian Liu, Dong‐Mei Guo, Yan Wang, Wen‐Hui Zha, Yang Li & Fu‐Ju Wu. (2018)
Retracted
: TPX2 gene silencing inhibits cell proliferation and promotes apoptosis through negative regulation of AKT signaling pathway in ovarian cancer
. Journal of Cellular Biochemistry 119:9, pages 7540-7555.
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Vladimir JoukovArcangela De Nicolo. (2018) Aurora-PLK1 cascades as key signaling modules in the regulation of mitosis. Science Signaling 11:543.
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Oliver Gruss. (2018) Animal Female Meiosis: The Challenges of Eliminating Centrosomes. Cells 7:7, pages 73.
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Patrick J. McIntyre, Patrick M. Collins, Lukáš Vrzal, Kristian Birchall, Laurence H. Arnold, Chido Mpamhanga, Peter J. Coombs, Selena G. Burgess, Mark W. Richards, Anja Winter, Václav Veverka, Frank von Delft, Andy Merritt & Richard Bayliss. (2017) Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. ACS Chemical Biology 12:11, pages 2906-2914.
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Italia Anna Asteriti, Frederick Daidone, Gianni Colotti, Serena Rinaldo, Patrizia Lavia, Giulia Guarguaglini & Alessandro Paiardini. (2017) Identification of small molecule inhibitors of the Aurora-A/TPX2 complex. Oncotarget 8:19, pages 32117-32133.
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Yana K. Rennie, Patrick J. McIntyre, Tito Akindele, Richard Bayliss & Andrew G. Jamieson. (2016) A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix. ACS Chemical Biology 11:12, pages 3383-3390.
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Luis Sanchez-Pulido, Laurent Perez, Steffen Kuhn, Isabelle Vernos & Miguel A. Andrade-Navarro. (2016) The C-terminal domain of TPX2 is made of alpha-helical tandem repeats. BMC Structural Biology 16:1.
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Georgina Garrido & Isabelle Vernos. (2016) Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell Division. Frontiers in Oncology 6.
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Gernot Neumayer & Minh Dang Nguyen. (2014) TPX2 Impacts Acetylation of Histone H4 at Lysine 16: Implications for DNA Damage Response. PLoS ONE 9:11, pages e110994.
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Gernot Neumayer, Camille Belzil, Oliver J. Gruss & Minh Dang Nguyen. (2014) TPX2: of spindle assembly, DNA damage response, and cancer. Cellular and Molecular Life Sciences 71:16, pages 3027-3047.
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Xiaolin Yang, Geling Liu, Hongzhen Xiao, Fang Yu, Xiuxiu Xiang, Yifang Lu, Weijuan Li, Xiuling Liu, Sha Li & Yanping Shi. (2014) TPX2 Overexpression in Medullary Thyroid Carcinoma Mediates TT Cell Proliferation. Pathology & Oncology Research 20:3, pages 641-648.
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Adelajda Zorba, Vanessa Buosi, Steffen Kutter, Nadja Kern, Francesco Pontiggia, Young-Jin Cho & Dorothee Kern. (2014) Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2. eLife 3.
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Oliver J. Gruss. 2014. Ras Superfamily Small G Proteins: Biology and Mechanisms 2. Ras Superfamily Small G Proteins: Biology and Mechanisms 2
125
148
.
Ignacio Pérez de Castro, Cristina Aguirre-Portolés, Gonzalo Fernández-Miranda, Marta Cañamero, Dale O. Cowley, Terry Van Dyke & Marcos Malumbres. (2013) Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals. Cancer Research 73:22, pages 6804-6815.
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José M. Arencibia, Daniel Pastor-Flores, Angelika F. Bauer, Jörg O. Schulze & Ricardo M. Biondi. (2013) AGC protein kinases: From structural mechanism of regulation to allosteric drug development for the treatment of human diseases. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1834:7, pages 1302-1321.
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Crossref
Sevil Zencir, Adam Sike, Melanie J. Dobson, Ferhan Ayaydin, Imre Boros & Zeki Topcu. (2013) Identification of transcriptional and phosphatase regulators as interaction partners of human ADA3, a component of histone acetyltransferase complexes. Biochemical Journal 450:2, pages 311-320.
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Richard Bayliss, Andrew Fry, Tamanna Haq & Sharon Yeoh. (2012) On the molecular mechanisms of mitotic kinase activation. Open Biology 2:11, pages 120136.
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Akihito Inoko, Makoto Matsuyama, Hidemasa Goto, Yuki Ohmuro-Matsuyama, Yuko Hayashi, Masato Enomoto, Miho Ibi, Takeshi Urano, Shigenobu Yonemura, Tohru Kiyono, Ichiro Izawa & Masaki Inagaki. (2012) Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells. Journal of Cell Biology 197:3, pages 391-405.
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Alex McDougall, Janet Chenevert & Remi Dumollard. 2012. International Review of Cell and Molecular Biology Volume 297. International Review of Cell and Molecular Biology Volume 297
235
264
.
Yuanhua Cheng, Fushi Zhang, Quan Chen, Jian Gao, Wei Cui, Mingjuan Ji & Chen-Ho Tung. (2011) Structural Basis of Specific Binding between Aurora A and TPX2 by Molecular Dynamics Simulations. Journal of Chemical Information and Modeling 51:10, pages 2626-2635.
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Dhanasekaran Karthigeyan, Sallekoppal B. Benaka Prasad, Jayasha Shandilya, Shipra Agrawal & Tapas K. Kundu. (2011) Biology of Aurora A kinase: Implications in cancer manifestation and therapy. Medicinal Research Reviews 31:5, pages 757-793.
Crossref
Crossref
Reiko Satow, Miki Shitashige, Yae Kanai, Fumitaka Takeshita, Hidenori Ojima, Takafumi Jigami, Kazufumi Honda, Tomoo Kosuge, Takahiro Ochiya, Setsuo Hirohashi & Tesshi Yamada. (2010) Combined Functional Genome Survey of Therapeutic Targets for Hepatocellular Carcinoma. Clinical Cancer Research 16:9, pages 2518-2528.
Crossref
Crossref
Mar Carmena, Sandrine Ruchaud & William C Earnshaw. (2009) Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins. Current Opinion in Cell Biology 21:6, pages 796-805.
Crossref
Crossref
Steven L. Warner, Bret J. Stephens, Stanley Nwokenkwo, Galen Hostetter, Anastasia Sugeng, Manuel Hidalgo, Jeffery M. Trent, Haiyong Han & Daniel D. Von Hoff. (2009) Validation of TPX2 as a Potential Therapeutic Target in Pancreatic Cancer Cells. Clinical Cancer Research 15:21, pages 6519-6528.
Crossref
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Fabienne HansDimitrios A. Skoufias, Stefan DimitrovRobert L. Margolis. (2009) Molecular Distinctions between Aurora A and B: A Single Residue Change Transforms Aurora A into Correctly Localized and Functional Aurora B. Molecular Biology of the Cell 20:15, pages 3491-3502.
Crossref
Crossref
Dmitri Demidov, Susann Hesse, Annegret Tewes, Twan Rutten, Jörg Fuchs, Raheleh Karimi Ashtiyani, Sandro Lein, Andreas Fischer, Gunter Reuter & Andreas Houben. (2009) Aurora1 phosphorylation activity on histone H3 and its cross-talk with other post-translational histone modifications in Arabidopsis. The Plant Journal 59:2, pages 221-230.
Crossref
Crossref
Jingyan Fu, Minglei Bian, Junjun Liu, Qing Jiang & Chuanmao Zhang. (2009) A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function. Proceedings of the National Academy of Sciences 106:17, pages 6939-6944.
Crossref
Crossref
Gaetan Pascreau, Frank Eckerdt, Andrea L. Lewellyn, Claude Prigent & James L. Maller. (2009) Phosphorylation of p53 Is Regulated by TPX2-Aurora A in Xenopus Oocytes. Journal of Biological Chemistry 284:9, pages 5497-5505.
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Crossref
E Vogt, A Kipp & U Eichenlaub-Ritter. (2009) Aurora kinase B, epigenetic state of centromeric heterochromatin and chiasma resolution in oocytes. Reproductive BioMedicine Online 19:3, pages 352-368.
Crossref
Crossref
Teresa Sardon, Isabel Peset, Boryana Petrova & Isabelle Vernos. (2008) Dissecting the role of Aurora A during spindle assembly. The EMBO Journal 27:19, pages 2567-2579.
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Crossref
Baoguang Zhao, Angela Smallwood, Jingsong Yang, Kristin Koretke, Kelvin Nurse, Amy Calamari, Robert B. Kirkpatrick & Zhihong Lai. (2008) Modulation of kinase-inhibitor interactions by auxiliary protein binding: Crystallography studies on Aurora A interactions with VX-680 and with TPX2. Protein Science 17:10, pages 1791-1797.
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Crossref
Tao-Wei Huang, Chung-Yen Lin & Cheng-Yan Kao. (2007) Reconstruction of human protein interolog network using evolutionary conserved network. BMC Bioinformatics 8:1.
Crossref
Crossref
Jingyan Fu, Minglei Bian, Qing Jiang & Chuanmao Zhang. (2007) Roles of Aurora Kinases in Mitosis and Tumorigenesis. Molecular Cancer Research 5:1, pages 1-10.
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Nurhan Özlü, Martin Srayko, Kazuhisa Kinoshita, Bianca Habermann, Eileen T. O’Toole, Thomas Müller-Reichert, Natalie Schmalz, Arshad Desai & Anthony A. Hyman. (2005) An Essential Function of the C. elegans Ortholog of TPX2 Is to Localize Activated Aurora A Kinase to Mitotic Spindles. Developmental Cell 9:2, pages 237-248.
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