Citations (36)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Yuan Xie, Anqiang Wang, Jianzhen Lin, Liangcai Wu, Haohai Zhang, Xiaobo Yang, Xueshuai Wan, Ruoyu Miao, Xinting Sang & Haitao Zhao. (2017) Mps1/TTK: a novel target and biomarker for cancer. Journal of Drug Targeting 25:2, pages 112-118.
Read now
Read now
Xiaojuan Zhang, Qingqing Yin, Youguo Ling, Yanhong Zhang, Runlin Ma, Qingjun Ma, Cheng Cao, Hui Zhong, Xuedong Liu & Quanbin Xu. (2011) Two LXXLL motifs in the N terminus of Mps1 are required for Mps1 nuclear import during G2/M transition and sustained spindle checkpoint responses. Cell Cycle 10:16, pages 2742-2750.
Read now
Read now
Rachel William Anantha & James A. Borowiec. (2009) Mitotic crisis: The unmasking of a novel role for RPA. Cell Cycle 8:3, pages 357-361.
Read now
Read now
Articles from other publishers (33)
Piya Prajumwongs, Ratthaphong Phumphu, Orawan Waenphimai, Worachart Lert-itthiporn, Kulthida Vaeteewoottacharn, Sopit Wongkham, Yaovalux Chamgramol, Chawalit Pairojkul & Kanlayanee Sawanyawisuth. (2021) High Monopolar Spindle 1 Is Associated with Short Survival of Cholangiocarcinoma Patients and Enhances the Progression Via AKT and STAT3 Signaling Pathways. Biomedicines 9:1, pages 68.
Crossref
Crossref
Almuth F. Kessler, Jonas Feldheim, Dominik Schmitt, Julia J. Feldheim, Camelia M. Monoranu, Ralf-Ingo Ernestus, Mario Löhr & Carsten Hagemann. (2020) Monopolar Spindle 1 Kinase (MPS1/TTK) mRNA Expression is Associated with Earlier Development of Clinical Symptoms, Tumor Aggressiveness and Survival of Glioma Patients. Biomedicines 8:7, pages 192.
Crossref
Crossref
Hao Feng, Zhong-Yi Gu, Qin Li, Qiong-Hua Liu, Xiao-Yu Yang & Jun-Jie Zhang. (2019) Identification of significant genes with poor prognosis in ovarian cancer via bioinformatical analysis. Journal of Ovarian Research 12:1.
Crossref
Crossref
Shutao Wang, Muxin Zhang, Di Liang, Wei Sun, Chaozai Zhang, Mengnan Jiang, Junli Liu, Jiaguo Li, Chenchen Li, Xiaohong Yang & Xiaoping Zhou. (2019) Molecular design and anticancer activities of small-molecule monopolar spindle 1 inhibitors: A Medicinal chemistry perspective. European Journal of Medicinal Chemistry 175, pages 247-268.
Crossref
Crossref
Jamie L. King, Baotong Zhang, Yixiang Li, Kathy P. Li, Jianping J. Ni, Harold I. Saavedra & Jin-Tang Dong. (2018) TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer. Oncogenesis 7:9.
Crossref
Crossref
Matthew L. H. Chu & Patrick A. Eyers. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules
3189
3201
.
A Szymiczek, M Carbone, S Pastorino, A Napolitano, M Tanji, M Minaai, I Pagano, J M Mason, H I Pass, M R Bray, T W Mak & H Yang. (2017) Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma. Oncogene 36:46, pages 6501-6507.
Crossref
Crossref
Yuan Xie, Jian-Zhen Lin, An-Qiang Wang, Wei-Yu Xu, Jun-Yu Long, Yu-Feng Luo, Jie Shi, Zhi-Yong Liang, Xin-Ting Sang & Hai-Tao Zhao. (2017) Threonine and tyrosine kinase may serve as a prognostic biomarker for gallbladder cancer. World Journal of Gastroenterology 23:31, pages 5787.
Crossref
Crossref
X Zhang, Y Ling, Y Guo, Y Bai, X Shi, F Gong, P Tan, Y Zhang, C Wei, X He, A Ramirez, X Liu, C Cao, H Zhong, Q Xu & R Z Ma. (2016) Mps1 kinase regulates tumor cell viability via its novel role in mitochondria. Cell Death & Disease 7:7, pages e2292-e2292.
Crossref
Crossref
Uday Bhanu Maachani, Tamalee Kramp, Ryan Hanson, Shuping Zhao, Orieta Celiku, Uma Shankavaram, Riccardo Colombo, Natasha J. Caplen, Kevin Camphausen & Anita Tandle. (2015)
Targeting
MPS1
Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins
. Molecular Cancer Research 13:5, pages 852-862.
Crossref
Crossref
Bashar Ibrahim. (2015) Systems Biology Modeling of Five Pathways for Regulation and Potent Inhibition of the Anaphase-Promoting Complex (APC/C): Pivotal Roles for MCC and BubR1. OMICS: A Journal of Integrative Biology 19:5, pages 294-305.
Crossref
Crossref
Bashar Ibrahim. (2015) Toward a systems-level view of mitotic checkpoints. Progress in Biophysics and Molecular Biology 117:2-3, pages 217-224.
Crossref
Crossref
Bashar Ibrahim & Richard Henze. (2014) Active Transport Can Greatly Enhance Cdc20:Mad2 Formation. International Journal of Molecular Sciences 15:10, pages 19074-19091.
Crossref
Crossref
Bakhos A. Tannous, Mariam Kerami, Petra M. Van der Stoop, Nicholas Kwiatkowski, Jinhua Wang, Wenjun Zhou, Almuth F. Kessler, Grant Lewandrowski, Lotte Hiddingh, Nik Sol, Tonny Lagerweij, Laurine Wedekind, Johanna M. Niers, Marco Barazas, R. Jonas A. Nilsson, Dirk Geerts, Philip C. De Witt Hamer, Carsten Hagemann, W. Peter Vandertop, Olaf Van Tellingen, David P. Noske, Nathanael S. Gray & Thomas Würdinger. (2013) Effects of the Selective MPS1 Inhibitor MPS1-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs. JNCI: Journal of the National Cancer Institute 105:17, pages 1322-1331.
Crossref
Crossref
Bashar Ibrahim, Richard Henze, Gerd Gruenert, Matthew Egbert, Jan Huwald & Peter Dittrich. (2013) Spatial Rule-Based Modeling: A Method and Its Application to the Human Mitotic Kinetochore. Cells 2:3, pages 506-544.
Crossref
Crossref
TSUNG-FAN TUAN, CHENG-TA CHUNG, HSIAO-HUI TSOU, FONG-WEN CHEN, HENG-LIANG LIN, YIU-KAY LAI, WEN-SEN LEE, YU-SHENG CHAO, LING-LING HWANG & CHIUNG-TONG CHEN. (2012) Putative tumor metastasis-associated genes in human gastric cancer. International Journal of Oncology 41:3, pages 1068-1084.
Crossref
Crossref
Stephan Kirchner. 2012. Polypharmacology in Drug Discovery. Polypharmacology in Drug Discovery
63
81
.
Matthew L. H. Chu & Patrick A. Eyers. 2012. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules
1103
1114
.
Chang Liu, Dewald van Dyk, Vitnary Choe, Jing Yan, Shubhra Majumder, Michael Costanzo, Xin Bao, Charles Boone, Keke Huo, Mark Winey, Harold Fisk, Brenda Andrews & Hai Rao. (2011) Ubiquitin Ligase Ufd2 Is Required for Efficient Degradation of Mps1 Kinase. Journal of Biological Chemistry 286:51, pages 43660-43667.
Crossref
Crossref
Marcos Malumbres. (2011) Physiological Relevance of Cell Cycle Kinases. Physiological Reviews 91:3, pages 973-1007.
Crossref
Crossref
Amanda N Pike & Harold A Fisk. (2011) Centriole assembly and the role of Mps1: defensible or dispensable?. Cell Division 6:1, pages 9.
Crossref
Crossref
Tingting Sun, Xiaomei Yang, Wei Wang, Xiaojuan Zhang, Quanbin Xu, Songcheng Zhu, Robert Kuchta, Guanjun Chen & Xuedong Liu. (2010) Cellular Abundance of Mps1 and the Role of Its Carboxyl Terminal Tail in Substrate Recruitment. Journal of Biological Chemistry 285:49, pages 38730-38739.
Crossref
Crossref
Wei Wang, Yuting Yang, Yuefeng Gao, Quanbin Xu, Feng Wang, Songcheng Zhu, William Old, Katheryn Resing, Natalie Ahn, Ming Lei & Xuedong Liu. (2008) Structural and mechanistic insights into Mps1 kinase activation. Journal of Cellular and Molecular Medicine 13:8b, pages 1679-1694.
Crossref
Crossref
Y-H Yeh, Y-F Huang, T-Y Lin & S-Y Shieh. (2009) The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1. Oncogene 28:10, pages 1366-1378.
Crossref
Crossref
Christopher Kasbek, Ching-Hui Yang & Harold A. Fisk. 2009. The Protein Protocols Handbook. The Protein Protocols Handbook
827
833
.
Matthew L.H. Chu, Leonard M.G. Chavas, Kenneth T. Douglas, Patrick A. Eyers & Lydia Tabernero. (2008) Crystal Structure of the Catalytic Domain of the Mitotic Checkpoint Kinase Mps1 in Complex with SP600125. Journal of Biological Chemistry 283:31, pages 21495-21500.
Crossref
Crossref
Anthony Tighe, Oliver Staples & Stephen Taylor. (2008) Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores. The Journal of Cell Biology 181:6, pages 893-901.
Crossref
Crossref
Matthew A. Trammell, Nicole M. Mahoney, David A. Agard & Ronald D. Vale. (2008)
Mob4 plays a role in spindle focusing in
Drosophila
S2 cells
. Journal of Cell Science 121:8, pages 1284-1292.
Crossref
Crossref
Elly M. Tanaka & Gilbert Weidinger. (2008) Micromanaging regeneration. Genes & Development 22:6, pages 700-705.
Crossref
Crossref
Marcos Malumbres & Mariano Barbacid. (2007) Cell cycle kinases in cancer. Current Opinion in Genetics & Development 17:1, pages 60-65.
Crossref
Crossref
Hiroshi Y. Yamada & Gary J. Gorbsky. (2006) Spindle checkpoint function and cellular sensitivity to antimitotic drugs. Molecular Cancer Therapeutics 5:12, pages 2963-2969.
Crossref
Crossref
Felix B. Engel, Michael Schebesta & Mark T. Keating. (2006) Anillin localization defect in cardiomyocyte binucleation. Journal of Molecular and Cellular Cardiology 41:4, pages 601-612.
Crossref
Crossref
Matthias G. Fischer, Sebastian Heeger, Udo Häcker & Christian F. Lehner. (2004) The Mitotic Arrest in Response to Hypoxia and of Polar Bodies during Early Embryogenesis Requires Drosophila Mps1. Current Biology 14:22, pages 2019-2024.
Crossref
Crossref