Citations (54)
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Jac A. Nickoloff, Neelam Sharma, Christopher P. Allen, Lynn Taylor, Sage J. Allen, Aruna S. Jaiswal & Robert Hromas. (2023) Roles of homologous recombination in response to ionizing radiation-induced DNA damage. International Journal of Radiation Biology 99:6, pages 903-914.
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Tingting Zhang, Yijun Shen, Ying Chen, Jer-Tsong Hsieh & Zhaolu Kong. (2015) The ATM inhibitor KU55933 sensitizes radioresistant bladder cancer cells with DAB2IP gene defect. International Journal of Radiation Biology 91:4, pages 368-378.
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Anthony J Berdis. (2014) Current and emerging strategies to increase the efficacy of ionizing radiation in the treatment of cancer. Expert Opinion on Drug Discovery 9:2, pages 167-181.
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Articles from other publishers (51)
Hui-Heng Lin, Hongyan Xu, Hongbo Hu, Zhanzhong Ma, Jie Zhou & Qingyun Liang. (2021) Predicting Ovarian/Breast Cancer Pathogenic Risks of Human BRCA1 Gene Variants of Unknown Significance. BioMed Research International 2021, pages 1-7.
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Crossref
Elodie Hatchi, Liana Goehring, Serena Landini, Konstantina Skourti-Stathaki, Derrick K. DeConti, Fieda O. Abderazzaq, Priyankana Banerjee, Timothy M. Demers, Yaoyu E. Wang, John Quackenbush & David M. Livingston. (2021) BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. Nature 591:7851, pages 665-670.
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Nalee Kim, Se Hoon Kim, Seok-Gu Kang, Ju Hyung Moon, Jaeho Cho, Chang-Ok Suh, Hong In Yoon & Jong Hee Chang. (2020) ATM mutations improve radio-sensitivity in wild-type isocitrate dehydrogenase-associated high-grade glioma: retrospective analysis using next-generation sequencing data. Radiation Oncology 15:1.
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Jac A. Nickoloff, Neelam Sharma & Lynn Taylor. (2020) Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy. Genes 11:1, pages 99.
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Shuyuan Zhang, Shuailin Hao, Zhiyu Qiu, Ya Wang, Yuqin Zhao, Youhang Li, Wen Gao, Yan Wu, Chang Liu, Xingzhi Xu & Hailong Wang. (2019) Cadmium disrupts the DNA damage response by destabilizing RNF168. Food and Chemical Toxicology 133, pages 110745.
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Stephen T. Durant, Li Zheng, Yingchun WangKan ChenLingli ZhangTianwei ZhangZhenfan YangLucy RichesAntonio G. TrinidadJacqueline H. L. Fok, Tom Hunt, Kurt G. PikeJoanne WilsonAaron SmithNicola ColcloughVenkatesh Pilla Reddy, Andrew Sykes, Annika Janefeldt, Peter JohnströmKatarina VarnäsAkihiro TakanoStephanie LingJonathan OrmeJonathan StottCaroline Roberts, Ian BarrettGemma JonesMartine Roudier, Andrew Pierce, Jasmine AllenJenna KahnAmrita SuleJeremy Karlin, Anna CroninMelissa ChapmanKristoffer Valerie, Ruth IllingworthMartin Pass. (2018) The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models. Science Advances 4:6.
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Yiying Wang, Yue Wang, Li Wei, Shuhui Hong, Miaoqing Zhao, Xi Zhang & Wenxin Zheng. (2017) BRCA1 expression, proliferative and apoptotic activities in ovarian epithelial inclusions. Journal of Ovarian Research 10:1.
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A.G Thivyah Prabha & Durairaj Sekar. (2017) Deciphering the molecular signaling pathways in breast cancer pathogenesis and their role in diagnostic and treatment modalities. Gene Reports 7, pages 1-17.
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Christopher P. Allen, Hirokazu Hirakawa, Nakako Izumi Nakajima, Sophia Moore, Jingyi Nie, Neelam Sharma, Mayumi Sugiura, Yuko Hoki, Ryoko Araki, Masumi Abe, Ryuichi Okayasu, Akira Fujimori & Jac A. Nickoloff. (2017) Low- and High-LET Ionizing Radiation Induces Delayed Homologous Recombination that Persists for Two Weeks before Resolving. Radiation Research 188:1, pages 82.
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Crossref
Stephen T. Durant. 2017. Encyclopedia of Cancer. Encyclopedia of Cancer
1
7
.
Janapriya Saha & Anthony J. Davis. (2016) Unsolved mystery: the role of BRCA1 in DNA end-joining. Journal of Radiation Research 57:S1, pages i18-i24.
Crossref
Crossref
Sandro Morganella, Ludmil B. Alexandrov, Dominik Glodzik, Xueqing Zou, Helen Davies, Johan Staaf, Anieta M. Sieuwerts, Arie B. Brinkman, Sancha Martin, Manasa Ramakrishna, Adam Butler, Hyung-Yong Kim, Åke Borg, Christos Sotiriou, P. Andrew Futreal, Peter J. Campbell, Paul N. Span, Steven Van Laere, Sunil R. Lakhani, Jorunn E. Eyfjord, Alastair M. Thompson, Hendrik G. Stunnenberg, Marc J. van de Vijver, John W. M. Martens, Anne-Lise Børresen-Dale, Andrea L. Richardson, Gu Kong, Gilles Thomas, Julian Sale, Cristina Rada, Michael R. Stratton, Ewan Birney & Serena Nik-Zainal. (2016) The topography of mutational processes in breast cancer genomes. Nature Communications 7:1.
Crossref
Crossref
Junho Ahn, Yeonweon Choi, Ae-Ree Lee, Joon-Hwa Lee & Jong Hwa Jung. (2016) A duplex DNA–gold nanoparticle probe composed as a colorimetric biosensor for sequence-specific DNA-binding proteins. The Analyst 141:6, pages 2040-2045.
Crossref
Crossref
A. Dasari, J.-S. Choi & A.J. Berdis. 2016. DNA Repair in Cancer Therapy. DNA Repair in Cancer Therapy
179
224
.
Nada Albarakati, Tarek M.A. Abdel-Fatah, Rachel Doherty, Roslin Russell, Devika Agarwal, Paul Moseley, Christina Perry, Arvind Arora, Nouf Alsubhi, Claire Seedhouse, Emad A. Rakha, Andrew Green, Graham Ball, Stephen Chan, Carlos Caldas, Ian O. Ellis & Srinivasan Madhusudan. (2015) Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy. Molecular Oncology 9:1, pages 204-217.
Crossref
Crossref
Jac A. Nickoloff. 2015. Stress Response Pathways in Cancer. Stress Response Pathways in Cancer
7
28
.
Catherine Charles, Amandine Nachtergael, Moustapha Ouedraogo, Alexandra Belayew & Pierre Duez. (2014) Effects of chemopreventive natural products on non-homologous end-joining DNA double-strand break repair. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 768, pages 33-41.
Crossref
Crossref
Stephen T. Durant. 2017. Encyclopedia of Cancer. Encyclopedia of Cancer
1382
1387
.
Stephen T. Durant. 2016. Encyclopedia of Cancer. Encyclopedia of Cancer
1
7
.
William Y. Lin, John H. Wilson & Yunfu Lin. (2013) Repair of chromosomal double-strand breaks by precise ligation in human cells. DNA Repair 12:7, pages 480-487.
Crossref
Crossref
Yannick Auclair & Stéphane Richard. (2013) The role of arginine methylation in the DNA damage response. DNA Repair 12:7, pages 459-465.
Crossref
Crossref
Guochun Jiang, Isabelle Plo, Tong Wang, Mohammad Rahman, Ju Hwan Cho, Eddy Yang, Bernard S. Lopez & Fen Xia. (2013) BRCA1-Ku80 Protein Interaction Enhances End-joining Fidelity of Chromosomal Double-strand Breaks in the G1 Phase of the Cell Cycle. Journal of Biological Chemistry 288:13, pages 8966-8976.
Crossref
Crossref
Hiroki Shima, Hidekazu Suzuki, Jiying Sun, Kazuteru Kono, Lin Shi, Aiko Kinomura, Yasunori Horikoshi, Tsuyoshi Ikura, Masae Ikura, Roland Kanaar, Kazuhiko Igarashi, Hisato Saitoh, Hitoshi Kurumizaka & Satoshi Tashiro. (2013) Activation of the SUMO modification system is required for the accumulation of RAD51 at sites containing DNA damage. Journal of Cell Science.
Crossref
Crossref
Dulcie Lai, Stacy Visser-Grieve & Xiaolong Yang. (2012) Tumour suppressor genes in chemotherapeutic drug response. Bioscience Reports 32:4, pages 361-374.
Crossref
Crossref
Catherine Charles, Moustapha Ouedraogo, Alexandra Belayew & Pierre Duez. (2012) On-chip microelectrophoresis for the study of in vitro nonhomologous end-joining DNA double-strand break repair. Analytical Biochemistry 425:1, pages 76-79.
Crossref
Crossref
Simon A. Joosse, Kim I. M. Brandwijk, Peter Devilee, Jelle Wesseling, Frans B. L. Hogervorst, Senno Verhoef & Petra M. Nederlof. (2010) Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH. Breast Cancer Research and Treatment 132:2, pages 379-389.
Crossref
Crossref
Anthony J. Berdis. 2012. DNA Repair in Cancer Therapy. DNA Repair in Cancer Therapy
75
107
.
Eric G. Thompson, Hanna Fares & Kathleen Dixon. (2011) BRCA1 requirement for the fidelity of plasmid DNA double‐strand break repair in cultured breast epithelial cells. Environmental and Molecular Mutagenesis 53:1, pages 32-43.
Crossref
Crossref
MM Ivanova, SM Abner, WM PierceJrJr & CM Klinge. (2011) Ligand-dependent differences in estrogen receptor beta-interacting proteins identified in lung adenocarcinoma cells corresponds to estrogenic responses. Proteome Science 9:1.
Crossref
Crossref
Zhigang Tu, Katherine M. Aird, Benjamin G. Bitler, Jasmine P. Nicodemus, Neil Beeharry, Bing Xia, Tim J. Yen & Rugang Zhang. (2011) Oncogenic Ras Regulates BRIP1 Expression to Induce Dissociation of BRCA1 from Chromatin, Inhibit DNA Repair, and Promote Senescence. Developmental Cell 21:6, pages 1077-1091.
Crossref
Crossref
Francesco Romeo, Lucia Falbo, Maddalena Di Sanzo, Roberta Misaggi, Maria C. Faniello, Giuseppe Viglietto, Giovanni Cuda, Francesco Costanzo & Barbara Quaresima. (2011) BRCA1 is required for hMLH1 stabilization following doxorubicin-induced DNA damage. The International Journal of Biochemistry & Cell Biology 43:12, pages 1754-1763.
Crossref
Crossref
Pavel RossnerJr.Jr., Katerina Uhlirova, Olena Beskid, Andrea Rossnerova, Vlasta Svecova & Radim J. Sram. (2011) Expression of XRCC5 in peripheral blood lymphocytes is upregulated in subjects from a heavily polluted region in the Czech Republic. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 713:1-2, pages 76-82.
Crossref
Crossref
R. Geoffrey SargentSoya KimDieter C. Gruenert. (2011) Oligo/Polynucleotide-Based Gene Modification: Strategies and Therapeutic Potential. Oligonucleotides 21:2, pages 55-75.
Crossref
Crossref
Stephen T. Durant. 2011. Encyclopedia of Cancer. Encyclopedia of Cancer
1129
1133
.
Narisorn Kongruttanachok, Chutipa Phuangphairoj, Araya Thongnak, Wanpen Ponyeam, Prakasit Rattanatanyong, Wichai Pornthanakasem & Apiwat Mutirangura. (2010) Replication independent DNA double-strand break retention may prevent genomic instability. Molecular Cancer 9:1.
Crossref
Crossref
Jessica M. Hair, Georgia I. Terzoudi, Vasiliki I. Hatzi, Katie A. Lehockey, Devika Srivastava, Weixin Wang, Gabriel E. Pantelias & Alexandros G. Georgakilas. (2010) BRCA1 role in the mitigation of radiotoxicity and chromosomal instability through repair of clustered DNA lesions. Chemico-Biological Interactions 188:2, pages 350-358.
Crossref
Crossref
Claudia E. Rübe, Andreas Fricke, Ruth Schneider, Karin Simon, Martin Kühne, Jochen Fleckenstein, Stefan Gräber, Norbert Graf & Christian Rübe. (2010) DNA Repair Alterations in Children With Pediatric Malignancies: Novel Opportunities to Identify Patients at Risk for High-Grade Toxicities. International Journal of Radiation Oncology*Biology*Physics 78:2, pages 359-369.
Crossref
Crossref
Jingsong Yuan, Rachel Adamski & Junjie Chen. (2010) Focus on histone variant H2AX: To be or not to be. FEBS Letters 584:17, pages 3717-3724.
Crossref
Crossref
Shay Covo, James W. Westmoreland, Dmitry A. Gordenin & Michael A. Resnick. (2010) Cohesin Is Limiting for the Suppression of DNA Damage–Induced Recombination between Homologous Chromosomes. PLoS Genetics 6:7, pages e1001006.
Crossref
Crossref
Kathleen M. Darcy & Michael J. Birrer. (2010) Translational research in the Gynecologic Oncology Group: Evaluation of ovarian cancer markers, profiles, and novel therapies. Gynecologic Oncology 117:3, pages 429-439.
Crossref
Crossref
Anastasia Zlatanou & Grant S. Stewart. (2010) A PIAS-ed view of DNA double strand break repair focuses on SUMO. DNA Repair 9:5, pages 588-592.
Crossref
Crossref
Julien Bouley, Cédric Pionneau, Justine Varinot, Denis Biard, Catherine Genestie, Martine Antoine, Florence Coulet, Marc‐Henri Stern, Dominique Stoppa‐Lyonnet & Florent Soubrier. (2010)
Proteomic analysis of BRCA1‐depleted cell line reveals a putative role for replication protein A2 up‐regulation in
BRCA1
breast tumor development
. PROTEOMICS – Clinical Applications 4:5, pages 489-498.
Crossref
Crossref
Jian-Jun Liu, Teng-Kai Chung, Jiali Li & Reshma Taneja. (2009) Sharp‐1 modulates the cellular response to DNA damage. FEBS Letters 584:3, pages 619-624.
Crossref
Crossref
Yaron Galanty, Rimma Belotserkovskaya, Julia Coates, Sophie Polo, Kyle M. Miller & Stephen P. Jackson. (2009) Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature 462:7275, pages 935-939.
Crossref
Crossref
Maria Adelaide Caligo, Fabrizia Bonatti, Lucia Guidugli, Paolo Aretini & Alvaro Galli. (2009)
A yeast recombination assay to characterize human
BRCA1
missense variants of unknown pathological significance
. Human Mutation 30:1, pages 123-133.
Crossref
Crossref
Grazia Ambrosini, Sharon L. Seelman, Li-Xuan Qin & Gary K. Schwartz. (2008) The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates the Effects of Topoisomerase I Poisons by Suppressing Rad51 Expression in a p53-Dependent Manner. Cancer Research 68:7, pages 2312-2320.
Crossref
Crossref
Meena Shrivastav, Leyma P De Haro & Jac A Nickoloff. (2007) Regulation of DNA double-strand break repair pathway choice. Cell Research 18:1, pages 134-147.
Crossref
Crossref
M. J. Franco, R. B. Sciurano & A. J. Solari. (2007) Protein immunolocalization supports the presence of identical mechanisms of XY body formation in eutherians and marsupials. Chromosome Research 15:6, pages 815-824.
Crossref
Crossref
Sanchita Krishna, Brant M. Wagener, Hui Ping Liu, Yi-Chen Lo, Rosa Sterk, John H.J. Petrini & Jac A. Nickoloff. (2007) Mre11 and Ku regulation of double-strand break repair by gene conversion and break-induced replication. DNA Repair 6:6, pages 797-808.
Crossref
Crossref
Sandeep Burma, Benjamin P.C. Chen & David J. Chen. (2006) Role of non-homologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair 5:9-10, pages 1042-1048.
Crossref
Crossref
Hui-Chun Wang, Wen-Cheng Chou, Sheau-Yann Shieh & Chen-Yang Shen. (2006) Ataxia Telangiectasia Mutated and Checkpoint Kinase 2 Regulate BRCA1 to Promote the Fidelity of DNA End-Joining. Cancer Research 66:3, pages 1391-1400.
Crossref
Crossref