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Perspectives

Interfering with MAP Kinase Docking Interactions: Implications and Perspectives for the p38 Route

Pages 528-533 | Published online: 15 Mar 2007

Keep up to date with the latest research on this topic with citation updates for this article.

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Gabriel Mbalaviele & Joseph B Monahan. (2008) Mechanisms of the joint-protective effects of p38 MAPK inhibitors in rodent arthritis. Expert Opinion on Drug Discovery 3:2, pages 163-172.
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M. JURADO-PUEYO, P. M. CAMPOS, F. MAYOR & C. MURGA. (2008) GRK2-Dependent Desensitization Downstream of G Proteins. Journal of Receptors and Signal Transduction 28:1-2, pages 59-70.
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Tapan Behl, Tarapati Rana, Ghallab H. Alotaibi, Md. Shamsuzzaman, Maaz Naqvi, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Yosif Almoshari, Ahmed A.H. Abdellatif, Muhammad Shahid Iqbal, Saurabh Bhatia, Ahmed Al-Harrasi & Simona Bungau. (2022) Polyphenols inhibiting MAPK signalling pathway mediated oxidative stress and inflammation in depression. Biomedicine & Pharmacotherapy 146, pages 112545.
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Seonghwan Hwang, Xiaolin Wang, Robim M. Rodrigues, Jing Ma, Yong He, Wonhyo Seo, Seol Hee Park, Seung‐Jin Kim, Dechun Feng & Bin Gao. (2020) Protective and Detrimental Roles of p38α Mitogen‐Activated Protein Kinase in Different Stages of Nonalcoholic Fatty Liver Disease. Hepatology 72:3, pages 873-891.
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Shannon Lee, Jens Rauch & Walter Kolch. (2020) Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity. International Journal of Molecular Sciences 21:3, pages 1102.
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Nour Yahfoufi, Nawal Alsadi, Majed Jambi & Chantal Matar. (2018) The Immunomodulatory and Anti-Inflammatory Role of Polyphenols. Nutrients 10:11, pages 1618.
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Pamela R. Cook & G. Travis Tabor. (2016) Deciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotransposition. Mobile DNA 7:1.
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Ashley A Brenton, Lattha Souvannaseng, Kong Cheung, Michael Anishchenko, Aaron C Brault & Shirley Luckhart. (2014) Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae. Parasites & Vectors 7:1.
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Naoki Kato, Masahito Matsumoto, Masakazu Kogawa, Gerald J Atkins, David M Findlay, Takahiko Fujikawa, Hiromi Oda & Masato Ogata. (2013) Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo. Journal of Neuroinflammation 10:1.
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Jing Li, Tamer S. Kaoud, Jake LeVieux, Brad Gilbreath, Swapna Moharana, Kevin N. Dalby & Sean M. Kerwin. (2013) A Fluorescence-Based Assay for p38α Recruitment Site Binders: Identification of Rooperol as a Novel p38α Kinase Inhibitor. ChemBioChem 14:1, pages 66-71.
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Lorena Palacios, Robin J. Dickinson, Almudena Sacristán-Reviriego, Mark P. Didmon, María José Marín, Humberto Martín, Stephen M. Keyse & María Molina. (2011) Distinct Docking Mechanisms Mediate Interactions between the Msg5 Phosphatase and Mating or Cell Integrity Mitogen-activated Protein Kinases (MAPKs) in Saccharomyces cerevisiae. Journal of Biological Chemistry 286:49, pages 42037-42050.
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Annemieke Kavelaars, Niels Eijkelkamp, Hanneke L.D.M. Willemen, Huijing Wang, Anibal Garza Carbajal & Cobi J. Heijnen. (2011) Microglial GRK2: A novel regulator of transition from acute to chronic pain. Brain, Behavior, and Immunity 25:6, pages 1055-1060.
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Hanbing An, Xinyuan Lu, Dan Liu & Wendell G. Yarbrough. (2011) LZAP Inhibits p38 MAPK (p38) Phosphorylation and Activity by Facilitating p38 Association with the Wild-Type p53 Induced Phosphatase 1 (WIP1). PLoS ONE 6:1, pages e16427.
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Jian-min Li, Pan Zhang, Ya-ning Zhao, Chang-xiang Chen & Shu-xing Li. (2011) Protective effects of edaravone on diffuse brain injury in rats. World Journal of Emergency Medicine 2:3, pages 222.
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Ana Cuadrado & Angel R. Nebreda. (2010) Mechanisms and functions of p38 MAPK signalling. Biochemical Journal 429:3, pages 403-417.
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Puji Astuti, Tanya Pike, Charlotte Widberg, Elizabeth Payne, Angus Harding, John Hancock & Brian Gabrielli. (2009) MAPK Pathway Activation Delays G2/M Progression by Destabilizing Cdc25B. Journal of Biological Chemistry 284:49, pages 33781-33788.
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Céline Tárrega & Rafael Pulido. (2009) A one-step method to identify MAP kinase residues involved in inactivation by tyrosine- and dual-specificity protein phosphatases. Analytical Biochemistry 394:1, pages 81-86.
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Rosalia Dettori, Silvina Sonzogni, Lucas Meyer, Laura A. Lopez-Garcia, Nick A. Morrice, Stefan Zeuzem, Matthias Engel, Albrecht Piiper, Sonja Neimanis, Morten Frödin & Ricardo M. Biondi. (2009) Regulation of the Interaction between Protein Kinase C-related Protein Kinase 2 (PRK2) and Its Upstream Kinase, 3-Phosphoinositide-dependent Protein Kinase 1 (PDK1). Journal of Biological Chemistry 284:44, pages 30318-30327.
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J. Jefferson P. Perry, Rodney M. Harris, Davide Moiani, Arthur J. Olson & John A. Tainer. (2009) p38α MAP Kinase C-Terminal Domain Binding Pocket Characterized by Crystallographic and Computational Analyses. Journal of Molecular Biology 391:1, pages 1-11.
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A. Jane Bardwell, Erlynn Frankson & Lee Bardwell. (2009) Selectivity of Docking Sites in MAPK Kinases. Journal of Biological Chemistry 284:19, pages 13165-13173.
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Tarek Boutros, Eric Chevet & Peter Metrakos. (2008) Mitogen-Activated Protein (MAP) Kinase/MAP Kinase Phosphatase Regulation: Roles in Cell Growth, Death, and Cancer. Pharmacological Reviews 60:3, pages 261-310.
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Radha Akella, Thomas M. Moon & Elizabeth J. Goldsmith. (2008) Unique MAP Kinase binding sites. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1784:1, pages 48-55.
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