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Fe-S coordination defects in the replicative DNA polymerase delta cause deleterious DNA replication
in vivo
and subsequent DNA damage in the yeast
Saccharomyces cerevisiae
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Zahra Salehi, Mohammad Keramatipour, Saeed Talebi, Seyed Shahriar Arab, Abdorreza Naser Moghadasi, Mohammad Ali Sahraian & Maryam Izad. (2021) Exome sequencing reveals novel rare variants in Iranian familial multiple sclerosis: The importance of POLD2 in the disease pathogenesis. Genomics 113:4, pages 2645-2655.
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Ilan AttaliMichael R. Botchan & James M. Berger. (2021) Structural Mechanisms for Replicating DNA in Eukaryotes. Annual Review of Biochemistry 90:1, pages 77-106.
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Keisuke Oki, Takeshi Yamagami, Mariko Nagata, Kouta Mayanagi, Tsuyoshi Shirai, Naruhiko Adachi, Tomoyuki Numata, Sonoko Ishino & Yoshizumi Ishino. (2021) DNA polymerase D temporarily connects primase to the CMG-like helicase before interacting with proliferating cell nuclear antigen. Nucleic Acids Research 49:8, pages 4599-4612.
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Radhika Malik, Mykhailo Kopylov, Yacob Gomez-Llorente, Rinku Jain, Robert E. Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia & Aneel K. Aggarwal. (2020) Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis. Nature Structural & Molecular Biology 27:10, pages 913-924.
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Xiaolu Ma, Tie‐Shan Tang & Caixia Guo. (2020) Regulation of translesion DNA synthesis in mammalian cells. Environmental and Molecular Mutagenesis 61:7, pages 680-692.
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Claudia Lancey, Muhammad Tehseen, Vlad-Stefan Raducanu, Fahad Rashid, Nekane Merino, Timothy J. Ragan, Christos G. Savva, Manal S. Zaher, Afnan Shirbini, Francisco J. Blanco, Samir M. Hamdan & Alfredo De Biasio. (2020) Structure of the processive human Pol δ holoenzyme. Nature Communications 11:1.
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Rinku Jain, William J. Rice, Radhika Malik, Robert E. Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia & Aneel K. Aggarwal. (2019) Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme. Nature Structural & Molecular Biology 26:10, pages 955-962.
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Cecilia Domínguez Conde, Özlem Yüce Petronczki, Safa Baris, Katharina L. Willmann, Enrico Girardi, Elisabeth Salzer, Stefan Weitzer, Rico Chandra Ardy, Ana Krolo, Hanna Ijspeert, Ayca Kiykim, Elif Karakoc-Aydiner, Elisabeth Förster-Waldl, Leo Kager, Winfried F. Pickl, Giulio Superti-Furga, Javier Martínez, Joanna I. Loizou, Ahmet Ozen, Mirjam van der Burg & Kaan Boztug. (2019) Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress. Journal of Clinical Investigation 129:10, pages 4194-4206.
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Jingyun Ji, Xiaona Tang, Wen Hu, Keith A. Maggert & Yikang S. Rong. (2019) The processivity factor Pol32 mediates nuclear localization of DNA polymerase delta and prevents chromosomal fragile site formation in Drosophila development. PLOS Genetics 15:5, pages e1008169.
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Amaia Gonzalez-Magaña, Alain Ibáñez de Opakua, Miguel Romano-Moreno, Javier Murciano-Calles, Nekane Merino, Irene Luque, Adriana L. Rojas, Silvia Onesti, Francisco J. Blanco & Alfredo De Biasio. (2019) The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA). Journal of Biological Chemistry 294:11, pages 3947-3956.
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