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Perspectives

JAK2 activation in myeloproliferative neoplasms: A potential role for heterodimeric receptors

Pages 714-719 | Published online: 31 Mar 2008

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Ping-Hung Chen, Fan-Ching Chien, Sue-Ping Lee, Woan-Eng Chan, I-Hsuan Lin, Chun-Shan Liu, Fang-Jen Lee, Jiann-Shiun Lai, Peilin Chen, Hsin-Fang yang-yen & Jeffrey Yen. (2012) Identification of a novel function of the clathrin-coated structure at the plasma membrane in facilitating GM-CSF receptor-mediated activation of JAK2. Cell Cycle 11:19, pages 3611-3626.
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Zari Tahannejad Asadi, Reza Yarahmadi, Najmaldin Saki, Mohammad Taha Jalali, Ali Amin Asnafi & Raheleh Tangestani. (2019) Investigation of JAK2V617F Mutation Prevalence in Patients with Beta Thalassemia Major. Laboratory Medicine.
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Takayuki Yoshimoto, Yukino Chiba, Jun‐Ichi Furusawa, Mingli Xu, Ren Tsunoda, Kaname Higuchi & Izuru Mizoguchi. (2015) Potential clinical application of interleukin‐27 as an antitumor agent. Cancer Science 106:9, pages 1103-1110.
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Ahmed E. Goda, Raymond L. Erikson, Toshiyuki Sakai, Jong-Seog Ahn & Bo-Yeon Kim. (2015) Preclinical evaluation of bortezomib/dipyridamole novel combination as a potential therapeutic modality for hematologic malignancies. Molecular Oncology 9:1, pages 309-322.
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Kunyan HeQi QiChi-Bun ChanGe XiaoXia LiuCarol Tucker-BurdenLiya WangHui MaoXiang LuFrank E. McDonaldHongbo LuoQi-Wen FanWilliam A. WeissShi-Yong SunDaniel J. BratKeqiang Ye. (2013) Blockade of Glioma Proliferation Through Allosteric Inhibition of JAK2. Science Signaling 6:283.
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M del Rey, K O'Hagan, M Dellett, S Aibar, H A A Colyer, M E Alonso, M Díez-Campelo, R N Armstrong, D J Sharpe, N C Gutiérrez, J L García, J De Las Rivas, K I Mills & J M Hernández-Rivas. (2012) Genome-wide profiling of methylation identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes. Leukemia 27:3, pages 610-618.
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J. Devon Roll & Gary W. Reuther. (2010) CRLF2 and JAK2 in B-Progenitor Acute Lymphoblastic Leukemia: A Novel Association in Oncogenesis. Cancer Research 70:19, pages 7347-7352.
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Anuradha Pradhan, Que T. Lambert, Lori N. Griner & Gary W. Reuther. (2010) Activation of JAK2-V617F by Components of Heterodimeric Cytokine Receptors. Journal of Biological Chemistry 285:22, pages 16651-16663.
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Yongchao WangWarren FiskusDaniel G. ChongKathleen M. BuckleyKavita NatarajanRekha RaoAtul JoshiRamesh BalusuSanjay KoulJianguang ChenAndrew SavoieCelalettin UstunAnand P. JillellaPeter Atadja, Ross L. Levine & Kapil N. Bhalla. (2009) Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells. Blood 114:24, pages 5024-5033.
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