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Deciphering the chromatin landscape induced around DNA double strand breaks

Pages 3035-3044 | Published online: 01 Aug 2010

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Read on this site (3)

Aude Guénolé & Gaëlle Legube. (2017) A meeting at risk: Unrepaired DSBs go for broke. Nucleus 8:6, pages 589-599.
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T Clouaire & G Legube. (2015) DNA double strand break repair pathway choice: a chromatin based decision?. Nucleus 6:2, pages 107-113.
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Dorine Rossetto, Nikita Avvakumov & Jacques Côté. (2012) Histone phosphorylation. Epigenetics 7:10, pages 1098-1108.
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Articles from other publishers (43)

Tim Heemskerk, Gerarda van de Kamp, Jeroen Essers, Roland Kanaar & Maarten W. Paul. (2023) Multi-scale cellular imaging of DNA double strand break repair. DNA Repair 131, pages 103570.
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Adele Alagia, Ruth F. Ketley & Monika Gullerova. (2023) Detecting RNA-protein proximity at DNA double-strand breaks using combined fluorescence in situ hybridization with proximity ligation assay. STAR Protocols 4:1, pages 102096.
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Ajit K. Sharma, Amira Mohammed Fitieh, Andrew J. Locke, Jana Yasser Hafez Ali & Ismail Hassan Ismail. (2023) Quantification of protein enrichment at site-specific DNA double-strand breaks by chromatin immunoprecipitation in cultured human cells. STAR Protocols 4:1, pages 101917.
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Ajit K. Sharma, Amira Mohammed Fitieh, Jana Yasser Hafez Ali & Ismail Hassan Ismail. (2022) Protocol to measure end resection intermediates at sequence-specific DNA double-strand breaks by quantitative polymerase chain reaction using ER-AsiSI U2OS cells. STAR Protocols 3:4, pages 101861.
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Ruth F. Ketley, Federica Battistini, Adele Alagia, Clémence Mondielli, Florence Iehl, Esra Balikçi, Kilian V.M. Huber, Modesto Orozco & Monika Gullerova. (2022) DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation. Cell Reports 41:4, pages 111526.
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Ashleigh Solano, Jieqiong Lou, Lorenzo Scipioni, Enrico Gratton & Elizabeth Hinde. (2022) Radial pair correlation of molecular brightness fluctuations maps protein diffusion as a function of oligomeric state within live-cell nuclear architecture. Biophysical Journal 121:11, pages 2152-2167.
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Ruben Schep, Christ Leemans, Eva K. Brinkman, Tom van Schaik & Bas van Steensel. (2022) Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair. Frontiers in Genetics 12.
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Jieqiong Lou, Ashleigh Solano, Zhen Liang & Elizabeth Hinde. (2021) Phasor Histone FLIM-FRET Microscopy Maps Nuclear-Wide Nanoscale Chromatin Architecture With Respect to Genetically Induced DNA Double-Strand Breaks. Frontiers in Genetics 12.
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Sunwoo Min, Ho-Soo Lee, Jae-Hoon Ji, Yungyeong Heo, Yonghyeon Kim, Sunyoung Chae, Yong Won Choi, Ho-Chul Kang, Makoto Nakanishi & Hyeseong Cho. (2021) The chromatin remodeler RSF1 coordinates epigenetic marks for transcriptional repression and DSB repair. Nucleic Acids Research 49:21, pages 12268-12283.
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Sonia Jimeno, Rosario Prados-Carvajal, María Jesús Fernández-Ávila, Sonia Silva, Domenico Alessandro Silvestris, Martín Endara-Coll, Guillermo Rodríguez-Real, Judit Domingo-Prim, Fernando Mejías-Navarro, Amador Romero-Franco, Silvia Jimeno-González, Sonia Barroso, Valeriana Cesarini, Andrés Aguilera, Angela Gallo, Neus Visa & Pablo Huertas. (2021) ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair. Nature Communications 12:1.
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Michael J. Cargill, Alicia Morales, Shashidhar Ravishankar & Edus H. Warren. (2021) RNA helicase, DDX3X, is actively recruited to sites of DNA damage in live cells. DNA Repair 103, pages 103137.
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Antao Chang, Liang Liu, Justin M. Ashby, Dan Wu, Yanan Chen, Stacey S. O'Neill, Shan Huang, Juan Wang, Guanwen Wang, Dongmei Cheng, Xiaoming Tan, W.J. Petty, Boris C. Pasche, Rong Xiang, Wei Zhang & Peiqing Sun. (2021) Recruitment of KMT2C/MLL3 to DNA Damage Sites Mediates DNA Damage Responses and Regulates PARP Inhibitor Sensitivity in Cancer. Cancer Research 81:12, pages 3358-3373.
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Sandrine Ragu, Gabriel Matos-Rodrigues, Melissa Thomas & Bernard S. Lopez. 2021. Genome Stability. Genome Stability 367 392 .
Yi Zhou & Tanya T. Paull. 2021. Homologous Recombination. Homologous Recombination 59 69 .
Zhongxing Sun, Yanjun Zhang, Junqi Jia, Yuan Fang, Yin Tang, Hongfei Wu & Dong Fang. (2020) H3K36me3, message from chromatin to DNA damage repair. Cell & Bioscience 10:1.
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Jieqiong Lou, David G. Priest, Ashleigh Solano, Adèle Kerjouan & Elizabeth Hinde. (2020) Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break. Nature Communications 11:1.
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Alexandra C. Vítor, Pablo Huertas, Gaëlle Legube & Sérgio F. de Almeida. (2020) Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox. Frontiers in Molecular Biosciences 7.
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Britta A. M. Bouwman & Nicola Crosetto. (2018) Endogenous DNA Double-Strand Breaks during DNA Transactions: Emerging Insights and Methods for Genome-Wide Profiling. Genes 9:12, pages 632.
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Federica M. Evangelista, Anne Maglott-Roth, Matthieu Stierle, Laurent Brino, Evi Soutoglou & László Tora. (2018) Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair. Journal of Cell Biology 217:10, pages 3382-3397.
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Valerio VitelliAlessandro GalbiatiFabio IannelliFabio PessinaSheetal SharmaFabrizio d'Adda di Fagagna. (2017) Recent Advancements in DNA Damage–Transcription Crosstalk and High-Resolution Mapping of DNA Breaks. Annual Review of Genomics and Human Genetics 18:1, pages 87-113.
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Aline Marnef, Sarah Cohen & Gaëlle Legube. (2017) Transcription-Coupled DNA Double-Strand Break Repair: Active Genes Need Special Care. Journal of Molecular Biology 429:9, pages 1277-1288.
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Ben R Hawley, Wei-Ting Lu, Ania Wilczynska & Martin Bushell. (2017) The emerging role of RNAs in DNA damage repair. Cell Death & Differentiation 24:4, pages 580-587.
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Jie Wen & Patrick Concannon. 2017. ATM Kinase. ATM Kinase 245 262 .
Veronika Mladenova, Emil Mladenov & George Iliakis. (2016) Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation. Frontiers in Oncology 6.
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Juliette Dabin, Anna Fortuny & Sophie E. Polo. (2016) Epigenome Maintenance in Response to DNA Damage. Molecular Cell 62:5, pages 712-727.
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Francesca Fallarino, Marco Gargaro, Giada Mondanell, Eric J. Downer, Md Jakir Hossain & Bruno Gran. 2016. Toll-Like Receptors. Toll-Like Receptors 383 411 .
Susanna Ambrosio, Stefano Amente, Giuliana Napolitano, Giacomo Di Palo, Luigi Lania & Barbara Majello. (2015) MYC impairs resolution of site-specific DNA double-strand breaks repair. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 774, pages 6-13.
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Hollie Chandler, Harshil Patel, Richard Palermo, Sharon Brookes, Nik Matthews & Gordon Peters. (2014) Role of Polycomb Group Proteins in the DNA Damage Response – A Reassessment. PLoS ONE 9:7, pages e102968.
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Kasper W.J. Derks, Jan H.J. Hoeijmakers & Joris Pothof. (2014) The DNA damage response: The omics era and its impact. DNA Repair 19, pages 214-220.
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François Aymard, Beatrix Bugler, Christine K Schmidt, Emmanuelle Guillou, Pierre Caron, Sébastien Briois, Jason S Iacovoni, Virginie Daburon, Kyle M Miller, Stephen P Jackson & Gaëlle Legube. (2014) Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks. Nature Structural & Molecular Biology 21:4, pages 366-374.
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Catherine Chailleux, François Aymard, Pierre Caron, Virginie Daburon, Céline Courilleau, Yvan Canitrot, Gaëlle Legube & Didier Trouche. (2014) Quantifying DNA double-strand breaks induced by site-specific endonucleases in living cells by ligation-mediated purification. Nature Protocols 9:3, pages 517-528.
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Yi Zhou, Pierre Caron, Gaëlle Legube & Tanya T. Paull. (2014) Quantitation of DNA double-strand break resection intermediates in human cells. Nucleic Acids Research 42:3, pages e19-e19.
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Yi Zhou & Tanya T. Paull. (2013) DNA-dependent Protein Kinase Regulates DNA End Resection in Concert with Mre11-Rad50-Nbs1 (MRN) and Ataxia Telangiectasia-mutated (ATM). Journal of Biological Chemistry 288:52, pages 37112-37125.
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Giuliana Napolitano, Stefano Amente, Miriam Lubrano Lavadera, Giacomo Di Palo, Susanna Ambrosio, Luigi Lania, Gaetano Ivan Dellino, Pier Giuseppe Pelicci & Barbara Majello. (2013) Sequence-specific double strand breaks trigger P-TEFb-dependent Rpb1-CTD hyperphosphorylation. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 749:1-2, pages 21-27.
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Young-Ho Lee, Ching-Ying Kuo, Jeremy M. Stark, Hsiu-Ming Shih & David K. Ann. (2013) HP1 promotes tumor suppressor BRCA1 functions during the DNA damage response. Nucleic Acids Research 41:11, pages 5784-5798.
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Gernot Neumayer, Angela Helfricht, Su Yeon Shim, Hoa Thi Le, Cecilia Lundin, Camille Belzil, Mathieu Chansard, Yaping Yu, Susan P. Lees-Miller, Oliver J. Gruss, Haico van Attikum, Thomas Helleday & Minh Dang Nguyen. (2012) Targeting Protein for Xenopus Kinesin-like Protein 2 (TPX2) Regulates γ-Histone 2AX (γ-H2AX) Levels upon Ionizing Radiation. Journal of Biological Chemistry 287:50, pages 42206-42222.
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Sham Sunder, Nikole T. Greeson-Lott, Kurt W. Runge & Steven L. Sanders. (2012) A new method to efficiently induce a site-specific double-strand break in the fission yeast Schizosaccharomyces pombe. Yeast 29:7, pages 275-291.
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Kyle M. MillerStephen P. Jackson. (2012) Histone marks: repairing DNA breaks within the context of chromatin. Biochemical Society Transactions 40:2, pages 370-376.
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Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian & Stephen P Jackson. (2012) Small-molecule–induced DNA damage identifies alternative DNA structures in human genes. Nature Chemical Biology 8:3, pages 301-310.
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Pierre Caron, Francois Aymard, Jason S. Iacovoni, Sébastien Briois, Yvan Canitrot, Beatrix Bugler, Laurent Massip, Ana Losada & Gaëlle Legube. (2012) Cohesin Protects Genes against γH2AX Induced by DNA Double-Strand Breaks. PLoS Genetics 8:1, pages e1002460.
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Roger A. Greenberg. (2011) Histone tails: Directing the chromatin response to DNA damage. FEBS Letters 585:18, pages 2883-2890.
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Sophie E. Polo & Stephen P. Jackson. (2011) Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes & Development 25:5, pages 409-433.
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Jeanette Rientjes, Jieqiong Lou, Menachem Gunzburg, Bradley Doak, Jacqueline Norris, Caroline Foley, Sarah N. Dishman, Stephanie Cholensky, Dirk Truman, Emily Kelly, Susan Thomas, Michelle Meilak, Alyce Lynas, Bec Hurley, Fleur Rodda, Casey Grist, Emma Rooney, Tanya Lennane, Leanne Hawkey, Ian Smyth, Kenneth Pearce, Elizabeth Hinde, Lindsey Ingerman James & Stephen Headey. (2020) A 53BP1 Inhibitory Compound Enhances CRISPR Efficiency for Generating Knock-In Mice. SSRN Electronic Journal.
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