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Hypoxia induces PTHrP gene transcription in human cancer cells through the HIF-2α

Pages 3747-3753 | Published online: 15 Sep 2010

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Yarden Zohar & Nicola J. Mabjeesh. (2023) Targeting HIF-1 for prostate cancer: a synthesis of preclinical evidence. Expert Opinion on Therapeutic Targets 27:8, pages 715-731.
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Ivano Amelio & Gerry Melino. (2012) The “Sharp” blade against HIF-mediated metastasis. Cell Cycle 11:24, pages 4530-4535.
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Articles from other publishers (20)

Cynthia Clemente-González & Amancio Carnero. (2022) Role of the Hypoxic-Secretome in Seed and Soil Metastatic Preparation. Cancers 14:23, pages 5930.
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Vera M. Todd, Lawrence A. VecchiIIIIII, Miranda E. Clements, Katherine P. Snow, Cayla D. Ontko, Lauren Himmel, Christopher Pinelli, Marjan Rafat & Rachelle W. Johnson. (2021) Hypoxia inducible factor signaling in breast tumors controls spontaneous tumor dissemination in a site-specific manner. Communications Biology 4:1.
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Philippe Clézardin, Rob Coleman, Margherita Puppo, Penelope Ottewell, Edith Bonnelye, Frédéric Paycha, Cyrille B. Confavreux & Ingunn Holen. (2021) Bone metastasis: mechanisms, therapies, and biomarkers. Physiological Reviews 101:3, pages 797-855.
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Courtney M. Edwards & Rachelle W. Johnson. (2021) From Good to Bad: The Opposing Effects of PTHrP on Tumor Growth, Dormancy, and Metastasis Throughout Cancer Progression. Frontiers in Oncology 11.
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Vera M. Todd & Rachelle W. Johnson. (2020) Hypoxia in bone metastasis and osteolysis. Cancer Letters 489, pages 144-154.
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Vera Todd & Rachelle W. Johnson. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 243 253 .
Cerise Yuen-Ki Chan, Vincent Wai-Hin Yuen & Carmen Chak-Lui Wong. 2019. Hypoxia and Cancer Metastasis. Hypoxia and Cancer Metastasis 97 112 .
Ying Liu, Gabrielle E. Ciotti & T. S. Karin Eisinger-Mathason. 2019. Hypoxia and Cancer Metastasis. Hypoxia and Cancer Metastasis 57 69 .
Keren Tazat, Susanne Schindler, Reinhard Depping & Nicola J. Mabjeesh. (2018) Septin 9 isoform 1 (SEPT9_i1) specifically interacts with importin‐α7 to drive hypoxia‐inducible factor (HIF)‐1α nuclear translocation. Cytoskeleton 76:1, pages 123-130.
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Toru Hiraga. (2018) Hypoxic Microenvironment and Metastatic Bone Disease. International Journal of Molecular Sciences 19:11, pages 3523.
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Joaquín Araos, Jonathan P. Sleeman & Boyan K. Garvalov. (2018) The role of hypoxic signalling in metastasis: towards translating knowledge of basic biology into novel anti-tumour strategies. Clinical & Experimental Metastasis 35:7, pages 563-599.
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Daniele Gilkes. (2016) Implications of Hypoxia in Breast Cancer Metastasis to Bone. International Journal of Molecular Sciences 17:10, pages 1669.
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Erinn B. Rankin, Jin-Min Nam & Amato J. Giaccia. (2016) Hypoxia: Signaling the Metastatic Cascade. Trends in Cancer 2:6, pages 295-304.
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Rachelle W. Johnson, Ernestina Schipani & Amato J. Giaccia. (2015) HIF targets in bone remodeling and metastatic disease. Pharmacology & Therapeutics 150, pages 169-177.
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Sylwia Bartoszewska, Kinga Rochan, Arkadiusz Piotrowski, Wojciech Kamysz, Renata J. Ochocka, James F. Collawn & Rafal Bartoszewski. (2014) The hypoxia‐inducible miR‐429 regulates hypoxia‐inducible factor‐1α expression in human endothelial cells through a negative feedback loop. The FASEB Journal 29:4, pages 1467-1479.
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Michele PelosiStefano LazzaranoBrendan L. ThomsChris L. Murphy. (2013) Parathyroid hormone-related protein is induced by hypoxia and promotes expression of the differentiated phenotype of human articular chondrocytes. Clinical Science 125:10, pages 461-470.
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Dikla Vardi-Oknin, Maya Golan & Nicola J. Mabjeesh. (2013) Forchlorfenuron Disrupts SEPT9_i1 Filaments and Inhibits HIF-1. PLoS ONE 8:8, pages e73179.
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Carole Sourbier, Gaurav Srivastava, Manik C. Ghosh, Sanchari Ghosh, Youfeng Yang, Gopal Gupta, William DeGraff, Murali C. Krishna, James B. Mitchell, Tracey A. Rouault & W. Marston Linehan. (2012) Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma. Oncotarget 3:11, pages 1472-1482.
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. (2011) Current World Literature. Current Opinion in Endocrinology, Diabetes & Obesity 18:6, pages 418-424.
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Katrien De Bock, Massimiliano Mazzone & Peter Carmeliet. (2011) Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?. Nature Reviews Clinical Oncology 8:7, pages 393-404.
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