Citations (46)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
M. Michael Dcona, Benjamin L. Morris, Keith C. Ellis & Steven R. Grossman. (2017) CtBP- an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors. Cancer Biology & Therapy 18:6, pages 379-391.
Read now
Read now
Jagrut Patel, Somesh Baranwal, Ian M Love, Nirmita J Patel, Steven R Grossman & Bhaumik B Patel. (2014) Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells. Cell Cycle 13:22, pages 3506-3518.
Read now
Read now
Ling-zun Zhao & G. Chinnadurai. (2010) Incapacitating CtBP to kill cancer. Cell Cycle 9:18, pages 3660-3665.
Read now
Read now
Articles from other publishers (43)
Kranthi Kumar Chougoni, Haemin Park, Priyadarshan K. Damle, Travis Mason, Bo Cheng, Martin M. Dcona, Barbara Szomju, Mikhail G. Dozmorov, Michael O. Idowu & Steven R. Grossman. (2023) Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma. Oncogenesis 12:1.
Crossref
Crossref
Varsha Singh, Amit Katiyar, Prabhat Malik, Sunil Kumar, Anant Mohan, Harpreet Singh & Deepali Jain. (2023) Identification of molecular biomarkers associated with non-small-cell lung carcinoma (NSCLC) using whole-exome sequencing. Cancer Biomarkers, pages 1-18.
Crossref
Crossref
Cláudia Saraiva, Jéssica Lopes-Nunes, Marta Esteves, Tiago Santos, Ana Vale, Ana Clara Cristóvão, Raquel Ferreira & Liliana Bernardino. (2023) CtBP Neuroprotective Role in Toxin-Based Parkinson’s Disease Models: From Expression Pattern to Dopaminergic Survival. Molecular Neurobiology 60:8, pages 4246-4260.
Crossref
Crossref
Yao Chen, Xiaoqin Lu, Ling Gao, Douglas C. Dean & Yongqing Liu. (2022) Spheroid-induced heterogeneity and plasticity of uveal melanoma cells. Cellular Oncology 45:2, pages 309-321.
Crossref
Crossref
Marcella Bonanomi, Noemi Salmistraro, Giulia Fiscon, Federica Conte, Paola Paci, Valentina Bravatà, Giusi Irma Forte, Tatiana Volpari, Manuela Scorza, Fabrizia Mastroianni, Stefano D’Errico, Elenio Avolio, Gennaro Piccialli, Anna Maria Colangelo, Marco Vanoni, Daniela Gaglio & Lilia Alberghina. (2021) Transcriptomics and Metabolomics Integration Reveals Redox-Dependent Metabolic Rewiring in Breast Cancer Cells. Cancers 13:20, pages 5058.
Crossref
Crossref
Rupa Haldavnekar, Krishnan Venkatakrishnan & Dr Bo Tan. (2021) Boosting the sub-cellular biomolecular cancer signals by self-functionalized tag-free nano sensor. Biosensors and Bioelectronics 190, pages 113407.
Crossref
Crossref
Zhi Chen. (2021) The transrepression and transactivation roles of CtBPs in the pathogenesis of different diseases. Journal of Molecular Medicine 99:10, pages 1335-1347.
Crossref
Crossref
Yingnan Zhang, Xiao Liu, Wei Liang, Douglas C. Dean, Lijun Zhang & Yongqing Liu. (2021) Expression and Function of ZEB1 in the Cornea. Cells 10:4, pages 925.
Crossref
Crossref
Min Li, Suzette Riddle, Sushil Kumar, Joanna Poczobutt, B. Alexandre McKeon, Maria G. Frid, Maureen Ostaff, Julie A. Reisz, Travis Nemkov, Mehdi A. Fini, Aya Laux, Cheng-Jun Hu, Karim C. El Kasmi, Angelo D’Alessandro, R. Dale Brown, Hui Zhang & Kurt R. Stenmark. (2021) Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension. Frontiers in Immunology 12.
Crossref
Crossref
Mira Kreuzer, Arindam Banerjee, Charles N. Birts, Matthew Darley, Ali Tavassoli, Mircea Ivan & Jeremy P. Blaydes. (2020) Glycolysis, via NADH‐dependent dimerisation of CtBPs, regulates hypoxia‐induced expression of CAIX and stem‐like breast cancer cell survival. FEBS Letters 594:18, pages 2988-3001.
Crossref
Crossref
Lei Jin, Yingnan Zhang, Wei Liang, Xiaoqin Lu, Niloofar Piri, Wei Wang, Henry J. Kaplan, Douglas C. Dean, Lijun Zhang & Yongqing Liu. (2020) Zeb1 promotes corneal neovascularization by regulation of vascular endothelial cell proliferation. Communications Biology 3:1.
Crossref
Crossref
Yu Deng, Wanjun Guo, Guancheng Li, Shuang Li, Hong Li, Xinyan Li, Bei Niu, Mingzhu Song, Yamei Zhang, Zhijian Xu & Fulun Li. (2020) Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1. Journal of Breast Cancer 23:1, pages 20.
Crossref
Crossref
Jung S. Byun, Samson Park, Dae Ik Yi, Jee-Hye Shin, Sara Gil Hernandez, Stephen M. Hewitt, Marc C. Nicklaus, Megan L. Peach, Laura Guasch, Binwu Tang, Lalage M. Wakefield, Tingfen Yan, Ambar Caban, Alana Jones, Mohamed Kabbout, Nasreen Vohra, Anna María Nápoles, Sandeep Singhal, Ryan Yancey, Adriana De Siervi & Kevin Gardner. (2019) Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein. Cell Death & Disease 10:10.
Crossref
Crossref
Arindam Banerjee, Charles N Birts, Matthew Darley, Rachel Parker, Alex H Mirnezami, Jonathan West, Ramsey I Cutress, Stephen A Beers, Matthew J J Rose-Zerilli & Jeremy P Blaydes. (2019) Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization. Carcinogenesis 40:7, pages 871-882.
Crossref
Crossref
M. Michael Dcona, Priyadarshan K. Damle, Francisco Zarate-Perez, Benjamin L. Morris, Zaid Nawaz, Michael J. Dennis, Xiaoyan Deng, Sudha Korwar, Sahib J. Singh, Keith C. Ellis, William E. Royer, Dipankar Bandyopadhyay, Carlos Escalante & Steven R. Grossman. (2019) Active-Site Tryptophan, the Target of Antineoplastic C-Terminal Binding Protein Inhibitors, Mediates Inhibitor Disruption of CtBP Oligomerization and Transcription Coregulatory Activities. Molecular Pharmacology 96:1, pages 99-108.
Crossref
Crossref
Sophie A. Arthur, Jeremy P. Blaydes & Franchesca D. Houghton. (2019) Glycolysis Regulates Human Embryonic Stem Cell Self-Renewal under Hypoxia through HIF-2α and the Glycolytic Sensors CTBPs. Stem Cell Reports 12:4, pages 728-742.
Crossref
Crossref
Ayesha T. Chawla, Agnes D. Cororaton, Michael O. Idowu, Priyadarshan K. Damle, Barbara Szomju, Keith C. Ellis, Bhaumik B. Patel & Steven R. Grossman. (2018)
An intestinal stem cell niche in
Apc
mutated neoplasia targetable by CtBP inhibition
. Oncotarget 9:65, pages 32408-32418.
Crossref
Crossref
I-Ching Kuan, Sing-Yu Chen, Sheng-Yuan Chang & Chi-Yang Yu. (2017) Immobilization of d -amino acid oxidase via a biomimetic coating and its application for the production of 4-methylthio-2-oxobutyric acid. Journal of the Taiwan Institute of Chemical Engineers 79, pages 60-65.
Crossref
Crossref
Lu Chen, Yang Yang, Liwei Xu, Rui Liu & Yali Wang. (2017) Integrated gene expression profiling and chromatin immunoprecipitation followed by sequencing: Analysis of the C-terminal binding protein in breast cancer. Journal of Obstetrics and Gynaecology Research 43:9, pages 1472-1480.
Crossref
Crossref
E T Sumner, A T Chawla, A D Cororaton, J E Koblinski, R C Kovi, I M Love, B B Szomju, S Korwar, K C Ellis & S R Grossman. (2017) Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia. Oncogene 36:33, pages 4810-4816.
Crossref
Crossref
Melanie A. Blevins, Mingxia Huang & Rui Zhao. (2017) The Role of CtBP1 in Oncogenic Processes and Its Potential as a Therapeutic Target. Molecular Cancer Therapeutics 16:6, pages 981-990.
Crossref
Crossref
Min LiSuzette RiddleHui ZhangAngelo D’AlessandroAmanda FlocktonNatalie J. SerkovaKirk C. HansenRadu MoldovanB. Alexandre McKeonMaria FridSushil KumarHong LiHongbing LiuAngela CaánovasJuan F. MedranoMilton G. ThomasDijana IloskaLydie Plecitá-HlavatáPetr JežekSoni PullamsettiMehdi A. FiniKarim C. El KasmiQingHong ZhangKurt R. Stenmark. (2016) Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1. Circulation 134:15, pages 1105-1121.
Crossref
Crossref
Sudha Korwar, Benjamin L. Morris, Hardik I. Parikh, Robert A. Coover, Tyler W. Doughty, Ian M. Love, Brendan J. Hilbert, William E. RoyerJr.Jr., Glen E. Kellogg, Steven R. Grossman & Keith C. Ellis. (2016) Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP). Bioorganic & Medicinal Chemistry 24:12, pages 2707-2715.
Crossref
Crossref
Wenwen Wang, Guowei Zhang, Hui Gu, Ye Liu, Jifeng Lao, Kuifang Li & Huaijin Guan. (2015) Role of CtBP2 in the Apoptosis of Retinal Ganglion Cells. Cellular and Molecular Neurobiology 35:5, pages 633-640.
Crossref
Crossref
Melanie A. Blevins, Jennifer Kouznetsova, Aaron B. Krueger, Rebecca King, Lesley Mathews Griner, Xin Hu, Noel Southall, Juan J. Marugan, Qinghong Zhang, Marc Ferrer & Rui Zhao. (2015) Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression. SLAS Discovery 20:5, pages 663-672.
Crossref
Crossref
Brendan J. Hilbert, Benjamin L. Morris, Keith C. Ellis, Janet L. Paulsen, Celia A. Schiffer, Steven R. Grossman & William E. RoyerJr.Jr.. (2015) Structure-Guided Design of a High Affinity Inhibitor to Human CtBP. ACS Chemical Biology 10:4, pages 1118-1127.
Crossref
Crossref
L Wang, H Zhou, Y Wang, G Cui & L-j Di. (2015) CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4. Cell Death & Disease 6:1, pages e1620-e1620.
Crossref
Crossref
Brendan J. Hilbert, Steven R. Grossman, Celia A. Schiffer & William E. Royer. (2014) Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. FEBS Letters 588:9, pages 1743-1748.
Crossref
Crossref
Celine Debiais-Delpech, Julie Godet, Nathalie Pedretti, François-Xavier Bernard, Jacques Irani, Xavier Cathelineau, Olivier Cussenot & Gaelle Fromont. (2014) Expression patterns of candidate susceptibility genes HNF1β and CtBP2 in prostate cancer: Association with tumor progression. Urologic Oncology: Seminars and Original Investigations 32:4, pages 426-432.
Crossref
Crossref
Ling-Jun Zhao, T. Subramanian, S. Vijayalingam & G. Chinnadurai. (2014) CtBP2 proteome: Role of CtBP in E2F7-mediated repression and cell proliferation. Genes & Cancer 5:1-2, pages 31-40.
Crossref
Crossref
Dana L. Madison, Jacqueline A. Wirz, Don Siess & James R. Lundblad. (2013) Nicotinamide Adenine Dinucleotide-induced Multimerization of the Co-repressor CtBP1 Relies on a Switching Tryptophan. Journal of Biological Chemistry 288:39, pages 27836-27848.
Crossref
Crossref
Trisha R. Stankiewicz, Emily K. Schroeder, Natalie A. Kelsey, Ron J. Bouchard & Daniel A. Linseman. (2013) C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis. Molecular and Cellular Neuroscience 56, pages 322-332.
Crossref
Crossref
Taymaa May, Junzheng Yang, Melina Shoni, Shubai Liu, Housheng He, Reddy Gali, Shu-Kay Ng, Christopher Crum, Ross S. Berkowitz & Shu-Wing Ng. (2013) BRCA1 Expression Is Epigenetically Repressed in Sporadic Ovarian Cancer Cells by Overexpression of C-Terminal Binding Protein 2. Neoplasia 15:6, pages 600-IN6.
Crossref
Crossref
Petros D. Grivas & Athanasios G. Papavassiliou. (2012) Transcriptional corepressors in cancer. Cancer 119:6, pages 1120-1128.
Crossref
Crossref
Yuchan Wang, Fang Liu, Feng Mao, Qinlei Hang, Xiaodong Huang, Song He, Yingying Wang, Chun Cheng, Huijie Wang, Guangfei Xu, Tianyi Zhang & Aiguo Shen. (2013) Interaction with Cyclin H/Cyclin-dependent Kinase 7 (CCNH/CDK7) Stabilizes C-terminal Binding Protein 2 (CtBP2) and Promotes Cancer Cell Migration. Journal of Biological Chemistry 288:13, pages 9028-9034.
Crossref
Crossref
Ji Sun Lee & Soon Ji Yoo. (2013) C-terminus of Hsc70-interacting protein regulates C-terminal binding protein 2 and the expression of its target genes. Biochemical and Biophysical Research Communications 432:3, pages 418-424.
Crossref
Crossref
Li-Jun Di, Jung S. Byun, Madeline M. Wong, Clay Wakano, Tara Taylor, Sven Bilke, Songjoon Baek, Kent Hunter, Howard Yang, Maxwell Lee, Cecilia Zvosec, Galina Khramtsova, Fan Cheng, Charles M. Perou, C. Ryan Miller, Rachel Raab, Olufunmilayo I. Olopade & Kevin Gardner. (2013) Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer. Nature Communications 4:1.
Crossref
Crossref
Jung S. Byun & Kevin Gardner. (2013) C-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer. International Journal of Cell Biology 2013, pages 1-14.
Crossref
Crossref
Charles N. Birts, Sharandip K. Nijjar, Charlotte A. Mardle, Franciane Hoakwie, Patrick J. Duriez, Jeremy P. Blaydes & Ali Tavassoli. (2013) A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells. Chemical Science 4:8, pages 3046.
Crossref
Crossref
. 2013. Therapeutic Strategies in Cancer Biology and Pathology. Therapeutic Strategies in Cancer Biology and Pathology
217
288
.
Aristeidis G. Vaiopoulos, Ioannis D. Kostakis, Kalliopi Ch. Athanasoula & Athanasios G. Papavassiliou. (2012) Targeting transcription factor corepressors in tumor cells. Cellular and Molecular Life Sciences 69:11, pages 1745-1753.
Crossref
Crossref
Ahmed F. YousefGregory J. FonsecaMichael J. CohenJoe S. Mymryk. (2012) The C-terminal region of E1A: a molecular tool for cellular cartography. Biochemistry and Cell Biology 90:2, pages 153-163.
Crossref
Crossref
G. Chinnadurai. (2011) Opposing oncogenic activities of small DNA tumor virus transforming proteins. Trends in Microbiology 19:4, pages 174-183.
Crossref
Crossref