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Channels Volume 8, 2014 - Issue 2
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Research Paper

Pannexin1 channels act downstream of P2X7 receptors in ATP-induced murine T-cell death

Kenji F Shoji Departamento de Fisiología; Pontificia Universidad Católica de Chile; Santiago, Chile
,
Pablo J Sáez Departamento de Fisiología; Pontificia Universidad Católica de Chile; Santiago, Chile
,
Paloma A Harcha Departamento de Fisiología; Pontificia Universidad Católica de Chile; Santiago, Chile
,
Hector L Aguila Department of Immunology; University of Connecticut Health Center; Farmington, CT USA
&
Juan C Sáez Departamento de Fisiología; Pontificia Universidad Católica de Chile; Santiago, Chile; Instituto Milenio; Centro Interdisciplinario de Neurociencias de Valparaíso; Valparaíso, ChileCorrespondence[email protected]
Pages 142-156 | Received 30 Oct 2013, Accepted 05 Feb 2014, Published online: 03 Mar 2014

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Helen P Makarenkova, Sameer B Shah & Valery I Shestopalov. (2018) The two faces of pannexins: new roles in inflammation and repair. Journal of Inflammation Research 11, pages 273-288.
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Articles from other publishers (35)

Anne Caufriez, Arthur Lamouroux, Charlotte Martin, Debora Iaculli, Elif Ince Ergüç, Rafael Gozalbes, Maria D. Mayan, Brenda R. Kwak, Andrés Tabernilla, Mathieu Vinken & Steven Ballet. (2023) Determination of structural features that underpin the pannexin1 channel inhibitory activity of the peptide 10Panx1. Bioorganic Chemistry 138, pages 106612.
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Alessio Lissoni, Siyu Tao, Rosalie Allewaert, Katja Witschas & Luc Leybaert. (2023) Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and 10Panx1 Peptides. International Journal of Molecular Sciences 24:14, pages 11612.
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Rutambhara Purohit & Amal Kanti Bera. (2023) Carboxyl terminus of Pannexin-1 plays a crucial role in P2X7 receptor-mediated signaling. Biochemical and Biophysical Research Communications 664, pages 20-26.
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Michael Koval, Wyatt J. Schug & Brant E. Isakson. (2023) Pharmacology of pannexin channels. Current Opinion in Pharmacology 69, pages 102359.
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Daichi Kobayashi, Eiji Umemoto & Masayuki Miyasaka. (2023) The role of extracellular ATP in homeostatic immune cell migration. Current Opinion in Pharmacology 68, pages 102331.
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Anael Viana Pinto Alberto, Natiele Carla da Silva Ferreira, André Gustavo Calvano Bonavita, Oscar Kenji Nihei, Fernando Pires de Farias, Rodrigo da Cunha Bisaggio, Cristóvão de Albuquerque, Wilson Savino, Robson Coutinho-Silva, Pedro Muanis Persechini & Luiz Anastacio Alves. (2022) Physiologic roles of P2 receptors in leukocytes. Journal of Leukocyte Biology 112:5, pages 983-1012.
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Valerie J. Brock, Insa M. A. WolfMarco Er-Lukowiak, Niels Lory, Tobias Stähler, Lena-Marie WoelkHans-Willi Mittrücker, Christa E. Müller, Friedrich Koch-Nolte, Björn Rissiek, René Werner, Andreas H. Guse & Björn-Philipp Diercks. (2022) P2X4 and P2X7 are essential players in basal T cell activity and Ca 2+ signaling milliseconds after T cell activation . Science Advances 8:5.
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Paloma A. Harcha, Tamara López-López, Adrián G. Palacios & Pablo J. Sáez. (2021) Pannexin Channel Regulation of Cell Migration: Focus on Immune Cells. Frontiers in Immunology 12.
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Dale W. Laird & Silvia Penuela. (2021) Pannexin biology and emerging linkages to cancer. Trends in Cancer 7:12, pages 1119-1131.
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D. Ryan King, Meghan W. Sedovy, Xinyan Leng, Jianxiang Xue, Samy Lamouille, Michael Koval, Brant E. Isakson & Scott R. Johnstone. (2021) Mechanisms of Connexin Regulating Peptides. International Journal of Molecular Sciences 22:19, pages 10186.
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Derek J. Prince, Deendayal Patel & Scott C. Kachlany. (2021) Leukotoxin (LtxA/Leukothera) induces ATP expulsion via pannexin-1 channels and subsequent cell death in malignant lymphocytes. Scientific Reports 11:1.
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Yi-He Chen, Rong-Rong Lin & Qing-Qing Tao. (2021) The role of P2X7R in neuroinflammation and implications in Alzheimer's disease. Life Sciences 271, pages 119187.
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Eijaz Ahmed Bhat & Nasreena Sajjad. (2021) Human Pannexin 1 channel: Insight in structure–function mechanism and its potential physiological roles. Molecular and Cellular Biochemistry 476:3, pages 1529-1540.
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Peter Illes, Alexei Verkhratsky & Yong Tang. (2020) Pathological ATPergic Signaling in Major Depression and Bipolar Disorder. Frontiers in Molecular Neuroscience 12.
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Erica F. Diezmos, Irit Markus, D. S. Perera, Steven Gan, Li Zhang, Shaun L. Sandow, Paul P. Bertrand & Lu Liu. (2018) Blockade of Pannexin-1 Channels and Purinergic P2X7 Receptors Shows Protective Effects Against Cytokines-Induced Colitis of Human Colonic Mucosa. Frontiers in Pharmacology 9.
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Karin Dreisig, Louise Sund, Maja Wallentin Dommer, Nikolaj Pagh Kristensen, Kim Boddum, Rannveig Viste, Simon Fredholm, Niels Odum, Marja Jäättelä, Søren Skov & Birgitte R. Kornum. (2018) Human P2Y11 Expression Level Affects Human P2X7 Receptor-Mediated Cell Death. Frontiers in Immunology 9.
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Pablo J Sáez, Juan C Sáez, Ana-María Lennon-Duménil & Pablo Vargas. (2018) Role of calcium permeable channels in dendritic cell migration. Current Opinion in Immunology 52, pages 74-80.
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M. Verónica Donoso, Felipe Hernández, Tania Villalón, Claudio Acuña-Castillo & J. Pablo Huidobro-Toro. (2018) Pharmacological dissection of the cellular mechanisms associated to the spontaneous and the mechanically stimulated ATP release by mesentery endothelial cells: roles of thrombin and TRPV. Purinergic Signalling 14:2, pages 121-139.
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Gonzalo Gómez, Paola Fernández, Victoria Velarde & Juan Sáez. (2018) Angiotensin II-Induced Mesangial Cell Damage Is Preceded by Cell Membrane Permeabilization Due to Upregulation of Non-Selective Channels. International Journal of Molecular Sciences 19:4, pages 957.
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Jin Xu, Linxi Chen & Lanfang Li. (2018) Pannexin hemichannels: A novel promising therapy target for oxidative stress related diseases. Journal of Cellular Physiology 233:3, pages 2075-2090.
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Elisa Balboa, Fujiko Saavedra-Leiva, Luis A. Cea, Aníbal A. Vargas, Valeria Ramírez, Rosalba Escamilla, Juan C. Sáez & Tomás Regueira. (2018) Sepsis-Induced Channelopathy in Skeletal Muscles is Associated with Expression of Non-Selective Channels. Shock 49:2, pages 221-228.
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Jérôme Gilleron, Diane Carette, Dominique Segretain & Georges Pointis. (2018) Multiple and complex influences of connexins and pannexins on cell death. Biochimica et Biophysica Acta (BBA) - Biomembranes 1860:1, pages 182-191.
Crossref
Pablo J. Sáez, Pablo Vargas, Kenji F. Shoji, Paloma A. HarchaAna-María Lennon-Duménil & Juan C. Sáez. (2017) ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X 7 receptors . Science Signaling 10:506.
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Mauricio A. Retamal, Manuel A. Riquelme, Jimmy Stehberg & Julio Alcayaga. (2017) Connexin43 Hemichannels in Satellite Glial Cells, Can They Influence Sensory Neuron Activity?. Frontiers in Molecular Neuroscience 10.
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Carola J. Maturana, Adam Aguirre & Juan C. Sáez. (2017) High glucocorticoid levels during gestation activate the inflammasome in hippocampal oligodendrocytes of the offspring. Developmental Neurobiology 77:5, pages 625-642.
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Christine QuastChristina AlterZhaoping DingNadine BorgJürgen Schrader. (2017) Adenosine Formed by CD73 on T Cells Inhibits Cardiac Inflammation and Fibrosis and Preserves Contractile Function in Transverse Aortic Constriction–Induced Heart Failure. Circulation: Heart Failure 10:4.
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Ronald Sluyter. 2017. Protein Reviews. Protein Reviews 17 53 .
Erica F. Diezmos, Paul P. Bertrand & Lu Liu. (2016) Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins. Frontiers in Neuroscience 10.
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I. B. Semenova. (2016) ROLE OF PURINERGIC RECEPTORS IN IMMUNE RESPONSE. Journal of microbiology, epidemiology and immunobiology 93:2, pages 107-119.
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Manju Tewari & Pankaj Seth. (2015) Emerging role of P2X7 receptors in CNS health and disease. Ageing Research Reviews 24, pages 328-342.
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Andrew K.J. Boyce, Michelle S. Kim, Leigh E. Wicki-Stordeur & Leigh Anne Swayne. (2015) ATP stimulates pannexin 1 internalization to endosomal compartments. Biochemical Journal 470:3, pages 319-330.
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Juan C. Sáez, Bruno A. Cisterna, Anibal Vargas & Christopher P. Cardozo. (2015) Regulation of pannexin and connexin channels and their functional role in skeletal muscles. Cellular and Molecular Life Sciences 72:15, pages 2929-2935.
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Björn Rissiek, Friedrich Haag, Olivier Boyer, Friedrich Koch-Nolte & Sahil Adriouch. (2015) P2X7 on Mouse T Cells: One Channel, Many Functions. Frontiers in Immunology 6.
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Manuel A. Riquelme, Luis A. Cea, Jos?? L. Vega, Carlos Puebla, An??bal A. Vargas, Kenji F. Shoji, Mario Subiabre & Juan C. S??ez. (2015) Pannexin channels mediate the acquisition of myogenic commitment in C2C12 reserve cells promoted by P2 receptor activation. Frontiers in Cell and Developmental Biology 3.
Crossref
Pablo J. Sáez, Kenji F. Shoji, Adam Aguirre & Juan C. Sáez. (2014) Regulation of Hemichannels and Gap Junction Channels by Cytokines in Antigen-Presenting Cells. Mediators of Inflammation 2014, pages 1-23.
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