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Communicative & Integrative Biology Volume 6, 2013 - Issue 2

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Short Communication

c-Cbl reduces stability of rescued ∆F508-CFTR in human airway epithelial cells

Implications for cystic fibrosis treatment

Kristine M. Cihil Department of Nephrology; Children’s Hospital of Pittsburgh; Pittsburgh, PA USA

Andrew Zimnik Department of Nephrology; Children’s Hospital of Pittsburgh; Pittsburgh, PA USA

Agnieszka Swiatecka-Urban Department of Nephrology; Children’s Hospital of Pittsburgh; Pittsburgh, PA USA; Department of Cell Biology and Physiology; University of Pittsburgh School of Medicine; Pittsburgh, PA USACorrespondence[email protected]

Article: e23094 | Published online: 01 Mar 2013

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https://doi.org/10.4161/cib.23094

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Citations (7)

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Articles from other publishers (7)

Ryosuke Fukuda & Tsukasa Okiyoneda. (2018) Peripheral Protein Quality Control as a Novel Drug Target for CFTR Stabilizer. Frontiers in Pharmacology 9.
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Natalie Foot, Tanya Henshall & Sharad Kumar. (2017) Ubiquitination and the Regulation of Membrane Proteins. Physiological Reviews 97:1, pages 253-281.
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Carlos M. Farinha & Sara Canato. (2016) From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking. Cellular and Molecular Life Sciences 74:1, pages 39-55.
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Kavisha AroraSunitha YarlagaddaWeiqiang Zhang, ChangSuk MoonErin BouquetSaumini Srinivasan, Chunying Li, Dennis C. Stokes & Anjaparavanda P. Naren. (2016) Personalized medicine in cystic fibrosis: genistein supplementation as a treatment option for patients with a rare S1045Y-CFTR mutation. American Journal of Physiology-Lung Cellular and Molecular Physiology 311:2, pages L364-L374.
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Carlos M. Farinha, Agnieszka Swiatecka-Urban, David L. Brautigan & Peter Jordan. (2016) Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity. Frontiers in Chemistry 4.
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S.M. Lamothe & S. Zhang. 2016. Ubiquitination and Transmembrane Signaling. Ubiquitination and Transmembrane Signaling 161 223 .

Simão Luz, Kristine M. Cihil, David L. Brautigan, Margarida D. Amaral, Carlos M. Farinha & Agnieszka Swiatecka-Urban. (2014) LMTK2-mediated Phosphorylation Regulates CFTR Endocytosis in Human Airway Epithelial Cells. Journal of Biological Chemistry 289:21, pages 15080-15093.
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