1,801
Views
98
CrossRef citations to date
0
Altmetric
Mini Review

The regulation of synaptic function by α-synuclein

, , , , &
Pages 106-109 | Received 17 Dec 2009, Accepted 17 Dec 2009, Published online: 01 Mar 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Joseph J. H. Liang, Issa A. McKinnon & Catharine H. Rankin. (2020) The contribution of C. elegans neurogenetics to understanding neurodegenerative diseases. Journal of Neurogenetics 34:3-4, pages 527-548.
Read now
Andrea T. U. Schaefers & Gertraud Teuchert-Noodt. (2016) Developmental neuroplasticity and the origin of neurodegenerative diseases. The World Journal of Biological Psychiatry 17:8, pages 587-599.
Read now
Caroline Ran & Andrea Carmine Belin. (2014) The genetics of Parkinson’s disease: review of current and emerging candidates. Journal of Parkinsonism and Restless Legs Syndrome 4, pages 63-75.
Read now

Articles from other publishers (95)

Carter Lantz, Jaybree Lopez, Andrew K. Goring, Muhammad A. Zenaidee, Karl Biggs, Julian P. Whitelegge, Rachel R. Ogorzalek Loo, Frank-Gerrit Klärner, Thomas Schrader, Gal Bitan & Joseph A. Loo. (2023) Characterization of Molecular Tweezer Binding on α-Synuclein with Native Top-Down Mass Spectrometry and Ion Mobility-Mass Spectrometry Reveals a Mechanism for Aggregation Inhibition. Journal of the American Society for Mass Spectrometry 34:12, pages 2739-2747.
Crossref
Jenat Pazheparambil Jerom, Sooryalekshmi Madhukumar, Raveendran Harikumaran Nair & Sunilkumar Puthenpurackal Narayanan. (2023) Anti-amyloid potential of some phytochemicals against Aβ-peptide and α-synuclein, tau, prion, and Huntingtin protein. Drug Discovery Today 28:12, pages 103802.
Crossref
Sierra L Boyd, Nathan C Kuhn, Joseph R Patterson, Anna C Stoll, Sydney A Zimmerman, Mason R Kolanowski, Joseph J Neubecker, Kelvin C Luk, Eric S Ramsson, Caryl E Sortwell & Alison I Bernstein. (2023) Developmental exposure to the Parkinson’s disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice. Toxicological Sciences 196:1, pages 99-111.
Crossref
Fritjof Havemeister, Marziyeh Ghaeidamini & Elin K. Esbjörner. (2023) Monovalent cations have different effects on the assembly kinetics and morphology of α-synuclein amyloid fibrils. Biochemical and Biophysical Research Communications 679, pages 31-36.
Crossref
Richard M. Meade, Scott G. Allen, Christopher Williams, T.M. Simon Tang, Matthew P. Crump & Jody M. Mason. (2023) An N-terminal alpha-synuclein fragment binds lipid vesicles to modulate lipid-induced aggregation. Cell Reports Physical Science 4:9, pages 101563.
Crossref
Kristina Battis, Wei Xiang & Jürgen Winkler. (2023) The Bidirectional Interplay of α-Synuclein with Lipids in the Central Nervous System and Its Implications for the Pathogenesis of Parkinson’s Disease. International Journal of Molecular Sciences 24:17, pages 13270.
Crossref
Rachel Min Qi Lee & Tong-Wey Koh. (2023) Genetic modifiers of synucleinopathies—lessons from experimental models. Oxford Open Neuroscience 2.
Crossref
Jessica K. Smith, George D. Mellick & Alex M. Sykes. (2023) The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson’s disease. Frontiers in Cellular Neuroscience 16.
Crossref
Ramu Elango, Babajan Banaganapalli, Abdulrahman Mujalli, Nuha AlRayes, Sarah Almaghrabi, Majid Almansouri, Ahmed Sahly, Gada Ali Jadkarim, Md Zubbair Malik, Hussam Ibrahim Kutbi, Noor Ahmad Shaik & Eman Alefishat. (2023) Potential Biomarkers for Parkinson Disease from Functional Enrichment and Bioinformatic Analysis of Global Gene Expression Patterns of Blood and Substantia Nigra Tissues. Bioinformatics and Biology Insights 17, pages 117793222311662.
Crossref
Xue Gan, Jiahan Ren, Tianzhuang Huang, Kunhua Wu, Shulin Li, Yanchao Duan, Zhengbo Wang, Wei Si & Jingkuan Wei. (2023) Pathological α-synuclein accumulation, CSF metabolites changes and brain microstructures in cynomolgus monkeys treated with 6-hydroxydopamine. NeuroToxicology 94, pages 172-181.
Crossref
David J. Koss, Daniel Erskine, Andrew Porter, Pawel Palmoski, Hariharan Menon, Olivia G. J. Todd, Marta Leite, Johannes Attems & Tiago F. Outeiro. (2022) Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies. Acta Neuropathologica Communications 10:1.
Crossref
Kathryn J.C. Watt, Richard M. Meade, Robert J. Williams & Jody M. Mason. (2022) Anionic lipid vesicles have differential effects on the aggregation of early onset-associated α-synuclein missense mutants. Journal of Biological Chemistry 298:12, pages 102565.
Crossref
Bradley Roberts, Frances Theunissen, Francis L. Mastaglia, P. Anthony Akkari & Loren L. Flynn. (2022) Synucleinopathy in Amyotrophic Lateral Sclerosis: A Potential Avenue for Antisense Therapeutics?. International Journal of Molecular Sciences 23:16, pages 9364.
Crossref
Jordan Prahl & Gerhard A. Coetzee. (2022) Genetic Elements at the Alpha-Synuclein Locus. Frontiers in Neuroscience 16.
Crossref
Kathryn J. C. Watt, Richard M. Meade, Robert J. Williams & Jody M. Mason. (2022) Library-Derived Peptide Aggregation Modulators of Parkinson’s Disease Early-Onset α-Synuclein Variants. ACS Chemical Neuroscience 13:12, pages 1790-1804.
Crossref
Li Yang Tan, Kwan Hou Tang, Lynette Yu You Lim, Jia Xin Ong, Hyokeun Park & Sangyong Jung. (2022) α-Synuclein at the Presynaptic Axon Terminal as a Double-Edged Sword. Biomolecules 12:4, pages 507.
Crossref
Jordan Prahl, Steven E. Pierce, Gerhard A. Coetzee & Trevor Tyson. (2022) Alpha-synuclein negatively controls cell proliferation in dopaminergic neurons. Molecular and Cellular Neuroscience 119, pages 103702.
Crossref
Kasthuri Bai Magalingam, Sushela Devi Somanath, Shadab Md, Nagaraja Haleagrahara, Ju-Yen Fu, Kanga Rani Selvaduray & Ammu Kutty Radhakrishnan. (2022) Tocotrienols protect differentiated SH-SY5Y human neuroblastoma cells against 6-hydroxydopamine-induced cytotoxicity by ameliorating dopamine biosynthesis and dopamine receptor D2 gene expression. Nutrition Research 98, pages 27-40.
Crossref
Sinjan Choudhary, Manu Lopus & Ramakrishna V. Hosur. (2022) Targeting disorders in unstructured and structured proteins in various diseases. Biophysical Chemistry 281, pages 106742.
Crossref
Hayrettin Ozan Gulcan. (2022) Selected Natural and Synthetic Agents Effective against Parkinson’s Disease with Diverse Mechanisms. Current Topics in Medicinal Chemistry 22:3, pages 199-208.
Crossref
Alessia Sarchione, Antoine Marchand, Jean-Marc Taymans & Marie-Christine Chartier-Harlin. (2021) Alpha-Synuclein and Lipids: The Elephant in the Room?. Cells 10:9, pages 2452.
Crossref
Alida Amadeo, Sara Pizzi, Alessandro Comincini, Debora Modena, Alessandra Maria Calogero, Laura Madaschi, Gaia Faustini, Chiara Rolando, Arianna Bellucci, Gianni Pezzoli, Samanta Mazzetti & Graziella Cappelletti. (2021) The Association between α-Synuclein and α-Tubulin in Brain Synapses. International Journal of Molecular Sciences 22:17, pages 9153.
Crossref
Huimin Zheng, Changhe Shi, Haiyang Luo, Liyuan Fan, Zhihua Yang, Xinchao Hu, Zhongxian Zhang, Shuo Zhang, Zhengwei Hu, Yu Fan, Jing Yang, Chengyuan Mao & Yuming Xu. (2020) α-Synuclein in Parkinson’s Disease: Does a Prion-Like Mechanism of Propagation from Periphery to the Brain Play a Role?. The Neuroscientist 27:4, pages 367-387.
Crossref
Fatemeh Hadi, Hassan Akrami, Mehdi Totonchi, Abdolrazagh Barzegar, Seyed Massood Nabavi & Koorosh Shahpasand. (2021) α‐synuclein abnormalities trigger focal tau pathology, spreading to various brain areas in Parkinson disease. Journal of Neurochemistry 157:3, pages 727-751.
Crossref
Zhaoxia Liao, Zeqi Huang, Junhua Li, Hui Li, Liping Miao, Yanhui Liu, Jing Zhang, Ying Xu & Yujuan Li. (2021) Regulation of CRMP2 by Cdk5 and GSK-3β participates in sevoflurane-induced dendritic development abnormalities and cognitive dysfunction in developing rats. Toxicology Letters 341, pages 68-79.
Crossref
Zhaoxia Liao, Junhua Li, Liping Miao, Zeqi Huang, Wujian Huang, Yafang Liu & Yujuan Li. (2020) Inhibition of RhoA Activity Does Not Rescue Synaptic Development Abnormalities and Long-Term Cognitive Impairment After Sevoflurane Exposure. Neurochemical Research 46:3, pages 468-481.
Crossref
Areej G. Mesleh, Sara A. Abdulla & Omar El-Agnaf. (2021) Paving the Way toward Personalized Medicine: Current Advances and Challenges in Multi-OMICS Approach in Autism Spectrum Disorder for Biomarkers Discovery and Patient Stratification. Journal of Personalized Medicine 11:1, pages 41.
Crossref
Büşra Şengül, Erdinç Dursun, Alexei Verkhratsky & Duygu Gezen-Ak. (2020) Overexpression of α-Synuclein Reorganises Growth Factor Profile of Human Astrocytes. Molecular Neurobiology 58:1, pages 184-203.
Crossref
Jasmine CornishSamuel G. ChamberlainDarerca Owen & Helen R. Mott. (2020) Intrinsically disordered proteins and membranes: a marriage of convenience for cell signalling?. Biochemical Society Transactions 48:6, pages 2669-2689.
Crossref
Olivier Bousiges, Nathalie Philippi, Thomas Lavaux, Armand Perret-Liaudet, Ingolf Lachmann, Caroline Schaeffer-Agalède, Pierre Anthony, Anne Botzung, Lucie Rauch, Barbara Jung, Paulo Loureiro de Sousa, Catherine Demuynck, Catherine Martin-Hunyadi, Benjamin Cretin & Frédéric Blanc. (2020) Differential diagnostic value of total alpha-synuclein assay in the cerebrospinal fluid between Alzheimer’s disease and dementia with Lewy bodies from the prodromal stage. Alzheimer's Research & Therapy 12:1.
Crossref
Suzanne O. Nolan, Jennifer E. Zachry, Amy R. Johnson, Lillian J. Brady, Cody A. Siciliano & Erin S. Calipari. (2020) Direct dopamine terminal regulation by local striatal microcircuitry. Journal of Neurochemistry 155:5, pages 475-493.
Crossref
Ewa Papuć. (2020) Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?. Current Problems of Psychiatry 21:3, pages 161-166.
Crossref
Kathrin Kaehler, Hartwig Seitter, Adolf M. Sandbichler, Bettina Tschugg, Gerald J. Obermair, Nadia Stefanova & Alexandra Koschak. (2020) Assessment of the Retina of Plp-α-Syn Mice as a Model for Studying Synuclein-Dependent Diseases. Investigative Opthalmology & Visual Science 61:6, pages 12.
Crossref
Milica Bozic, Maite Caus, Raul R. Rodrigues-Diez, Neus Pedraza, Marta Ruiz-Ortega, Eloi Garí, Pilar Gallel, Maria José Panadés, Ana Martinez, Elvira Fernández & José Manuel Valdivielso. (2020) Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis. Nature Communications 11:1.
Crossref
Hea-Jong Chung, Mohammad Abu Hena Mostofa Jamal & Seong-Tshool Hong. (2020) The function of bacterial HtrA is evolutionally conserved in mammalian HtrA2/Omi. Scientific Reports 10:1.
Crossref
James Brown & Mathew H. Horrocks. (2020) A sticky situation: Aberrant protein–protein interactions in Parkinson’s disease. Seminars in Cell & Developmental Biology 99, pages 65-77.
Crossref
Hea-Jong Chung, Md. Saidul Islam, Md. Mashiar Rahman & Seong-Tshool Hong. (2020) Neuroprotective function of Omi to α-synuclein-induced neurotoxicity. Neurobiology of Disease 136, pages 104706.
Crossref
Janett Köppen, Anja Schulze, Lisa Machner, Michael Wermann, Rico Eichentopf, Max Guthardt, Angelika Hähnel, Jessica Klehm, Marie-Christin Kriegeskorte, Maike Hartlage-Rübsamen, Markus Morawski, Stephan von Hörsten, Hans-Ulrich Demuth, Steffen Roßner & Stephan Schilling. (2020) Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro. Molecules 25:3, pages 580.
Crossref
Ersoy Cholak, Saskia Bucciarelli, Katrine Bugge, Nicolai Tidemand Johansen, Bente Vestergaard, Lise Arleth, Birthe B. Kragelund & Annette E. Langkilde. (2019) Distinct α-Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior. Biochemistry 58:50, pages 5052-5065.
Crossref
Violetta Refolo & Nadia Stefanova. (2019) Neuroinflammation and Glial Phenotypic Changes in Alpha-Synucleinopathies. Frontiers in Cellular Neuroscience 13.
Crossref
Marcel Falke, Julian Victor, Michael M. Wördehoff, Alessia Peduzzo, Tao Zhang, Gunnar F. Schröder, Alexander K. Buell, Wolfgang Hoyer & Manuel Etzkorn. (2019) α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation. Chemistry and Physics of Lipids 220, pages 57-65.
Crossref
Eftychia Vasili, Antonio Dominguez-Meijide & Tiago Fleming Outeiro. (2019) Spreading of α-Synuclein and Tau: A Systematic Comparison of the Mechanisms Involved. Frontiers in Molecular Neuroscience 12.
Crossref
Rajesh R. Tampi, Juan Joseph Young & Deena Tampi. 2019. Psychopharmacology of Neurologic Disease. Psychopharmacology of Neurologic Disease 59 70 .
Wongyoung Lee, Soulmee Koh, Soondo Hwang & Sung Hyun Kim. (2018) Presynaptic Dysfunction by Familial Factors in Parkinson Disease. International Neurourology Journal 22:Suppl 3, pages S115-121.
Crossref
Thibault Viennet, Michael M. Wördehoff, Boran Uluca, Chetan Poojari, Hamed Shaykhalishahi, Dieter Willbold, Birgit Strodel, Henrike Heise, Alexander K. Buell, Wolfgang Hoyer & Manuel Etzkorn. (2018) Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation. Communications Biology 1:1.
Crossref
Boran Uluca, Thibault Viennet, Dušan Petrović, Hamed Shaykhalishahi, Franziska Weirich, Ayşenur Gönülalan, Birgit Strodel, Manuel Etzkorn, Wolfgang Hoyer & Henrike Heise. (2018) DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α -Synuclein in Different States. Biophysical Journal 114:7, pages 1614-1623.
Crossref
Hua Wang, Tessandra Stewart, Jon B. Toledo, Carmen Ginghina, Lu Tang, Anzari Atik, Patrick Aro, Leslie M. Shaw, John Q. Trojanowski, Douglas R. Galasko, Steven Edland, Poul H. Jensen, Min Shi & Jing Zhang. (2018) A Longitudinal Study of Total and Phosphorylated α-Synuclein with Other Biomarkers in Cerebrospinal Fluid of Alzheimer’s Disease and Mild Cognitive Impairment. Journal of Alzheimer's Disease 61:4, pages 1541-1553.
Crossref
Wilaiwan Sriwimol & Pornprot Limprasert. (2018) Significant Changes in Plasma Alpha-Synuclein and Beta-Synuclein Levels in Male Children with Autism Spectrum Disorder. BioMed Research International 2018, pages 1-7.
Crossref
Ingrid M. van der Wateren, Tuomas P. J. Knowles, Alexander K. Buell, Christopher M. Dobson & Céline Galvagnion. (2018) C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH. Chemical Science 9:25, pages 5506-5516.
Crossref
Ana Marta de Matos, Maria Paula de Macedo & Amélia Pilar Rauter. (2018) Bridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive Potential. Medicinal Research Reviews 38:1, pages 261-324.
Crossref
Desanka Milanovic, Vesna Pesic, Natasa Loncarevic-Vasiljkovic, Vladimir Avramovic, Vesna Tesic, Vesna Jevtovic-Todorovic, Selma Kanazir & Sabera Ruzdijic. (2017) Neonatal Propofol Anesthesia Changes Expression of Synaptic Plasticity Proteins and Increases Stereotypic and Anxyolitic Behavior in Adult Rats. Neurotoxicity Research 32:2, pages 247-263.
Crossref
Carl Mensch, Albert Konijnenberg, Roos Van Elzen, Anne-Marie Lambeir, Frank Sobott & Christian Johannessen. (2017) Raman optical activity of human α -synuclein in intrinsically disordered, micelle-bound α -helical, molten globule and oligomeric β -sheet state . Journal of Raman Spectroscopy 48:7, pages 910-918.
Crossref
Ismael Segura-Ulate, Barbara Yang, Javier Vargas-Medrano & Ruth G. Perez. (2017) FTY720 (Fingolimod) reverses α-synuclein-induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells. Neuropharmacology 117, pages 149-157.
Crossref
Sara Redenšek, Maja Trošt & Vita Dolžan. (2017) Genetic Determinants of Parkinson's Disease: Can They Help to Stratify the Patients Based on the Underlying Molecular Defect?. Frontiers in Aging Neuroscience 9.
Crossref
Reinis Svarcbahs, Ulrika H. Julku & Timo T. Myöhänen. (2016) Inhibition of Prolyl Oligopeptidase Restores Spontaneous Motor Behavior in the α-Synuclein Virus Vector–Based Parkinson's Disease Mouse Model by Decreasing α-Synuclein Oligomeric Species in Mouse Brain. The Journal of Neuroscience 36:49, pages 12485-12497.
Crossref
Nancy Stanslowsky, Peter Reinhardt, Hannes Glass, Norman Kalmbach, Maximilian Naujock, Niko Hensel, Verena Lübben, Arun Pal, Anna Venneri, Francesca Lupo, Lucia De Franceschi, Peter Claus, Jared Sterneckert, Alexander Storch, Andreas Hermann & Florian Wegner. (2016) Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization. The Journal of Neuroscience 36:47, pages 12027-12043.
Crossref
Marija Iljina, Laura Tosatto, Minee L. Choi, Jason C. Sang, Yu Ye, Craig D. Hughes, Clare E. Bryant, Sonia Gandhi & David Klenerman. (2016) Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein. Scientific Reports 6:1.
Crossref
Kathy B. Sheehan, MaryAnn Martin, Cammie F. Lesser, Ralph R. Isberg & Irene L. G. Newton. (2016) Identification and Characterization of a Candidate Wolbachia pipientis Type IV Effector That Interacts with the Actin Cytoskeleton. mBio 7:4.
Crossref
Aditya Iyer, Steven J. Roeters, Nathalie Schilderink, Bob Hommersom, Ron M.A. Heeren, Sander Woutersen, Mireille M.A.E. Claessens & Vinod Subramaniam. (2016) The Impact of N-terminal Acetylation of α-Synuclein on Phospholipid Membrane Binding and Fibril Structure. Journal of Biological Chemistry 291:40, pages 21110-21122.
Crossref
Ana West, Benjamin E. Brummel, Anthony R. Braun, Elizabeth Rhoades & Jonathan N. Sachs. (2016) Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein. Biochimica et Biophysica Acta (BBA) - Biomembranes 1858:7, pages 1594-1609.
Crossref
Ralph A. Nixon. 2016. Lysosomes: Biology, Diseases, and Therapeutics. Lysosomes: Biology, Diseases, and Therapeutics 137 179 .
Qi Xuan, Yu‑Xian Zhang, Dian‑Gang Liu, Piu Chan, Sheng‑Li Xu & Ye‑Qing Cui. (2016) Post-translational modifications of α-synuclein contribute to neurodegeneration in the colon of elderly individuals. Molecular Medicine Reports.
Crossref
Cornelius J. H. M. Klemann, Gerard J. M. Martens, Geert Poelmans & Jasper E. Visser. (2015) Validity of the MPTP-Treated Mouse as a Model for Parkinson’s Disease. Molecular Neurobiology 53:3, pages 1625-1636.
Crossref
Hongyan Xiao, Bing Liu, Yali Chen & Jun Zhang. (2015) Learning, memory and synaptic plasticity in hippocampus in rats exposed to sevoflurane. International Journal of Developmental Neuroscience 48:1, pages 38-49.
Crossref
Danielle D. Feng, Waijiao Cai & Xiqun Chen. (2015) The associations between Parkinson’s disease and cancer: the plot thickens. Translational Neurodegeneration 4:1.
Crossref
James M. Gruschus. (2015) Did α-Synuclein and Glucocerebrosidase Coevolve? Implications for Parkinson’s Disease. PLOS ONE 10:7, pages e0133863.
Crossref
Marco Emanuele & Evelina Chieregatti. (2015) Mechanisms of Alpha-Synuclein Action on Neurotransmission: Cell-Autonomous and Non-Cell Autonomous Role. Biomolecules 5:2, pages 865-892.
Crossref
Anja N. D. Stefanovic, Mireille M. A. E. Claessens, Christian Blum & Vinod Subramaniam. (2015) Alpha-Synuclein Amyloid Oligomers Act as Multivalent Nanoparticles to Cause Hemifusion in Negatively Charged Vesicles. Small 11:19, pages 2257-2262.
Crossref
Anke Van der Perren, Jaan Toelen, Cindy Casteels, Francesca Macchi, Anne-Sophie Van Rompuy, Sophie Sarre, Nicolas Casadei, Silke Nuber, Uwe Himmelreich, Maria Isabel Osorio Garcia, Yvette Michotte, Rudi D'Hooge, Guy Bormans, Koen Van Laere, Rik Gijsbers, Chris Van den Haute, Zeger Debyser & Veerle Baekelandt. (2015) Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors. Neurobiology of Aging 36:3, pages 1543-1558.
Crossref
Wei Xu, Lan Tan & Jin-Tai Yu. (2015) The link between the SNCA gene and parkinsonism. Neurobiology of Aging 36:3, pages 1505-1518.
Crossref
Amal Arachiche & Devrim Gozuacik. 2015. Toxicity and Autophagy in Neurodegenerative Disorders. Toxicity and Autophagy in Neurodegenerative Disorders 1 24 .
A. L. Schwarzman & S. V. Sarantseva. (2015) Pathology of synapses in neurological diseases. Biology Bulletin Reviews 4:6, pages 515-526.
Crossref
Shun Yu & Piu Chan. (2014) Role of α-synuclein in neurodegeneration: implications for the pathogenesis of Parkinson's disease. Essays in Biochemistry 56, pages 125-135.
Crossref
Mathieu Bourdenx, Erwan Bezard & Benjamin Dehay. (2014) Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. Frontiers in Neuroanatomy 8.
Crossref
Mary Ann Chapman. (2014) Interactions between cell adhesion and the synaptic vesicle cycle in Parkinson’s disease. Medical Hypotheses 83:2, pages 203-207.
Crossref
G.G. Kovacs, H. Adle-Biassette, I. Milenkovic, S. Cipriani, J. van Scheppingen & E. Aronica. (2014) Linking pathways in the developing and aging brain with neurodegeneration. Neuroscience 269, pages 152-172.
Crossref
Kumsal Ayse Tekirdag, Deniz Gulfem Ozturk & Devrim Gozuacik. (2013) Alteration in Autophagic-lysosomal Potential During Aging and Neurological Diseases: The microRNA Perspective. Current Pathobiology Reports 1:4, pages 247-261.
Crossref
Nari Shiokawa, Masayuki Nakamura, Mieko Sameshima, Akiko Deguchi, Takehiro Hayashi, Natsuki Sasaki & Akira Sano. (2013) Chorein, the protein responsible for chorea-acanthocytosis, interacts with β-adducin and β-actin. Biochemical and Biophysical Research Communications 441:1, pages 96-101.
Crossref
Guangwei Liu, Peng Wang, Xin Li, Yaohua Li, Shengli Xu, Kenji Uéda, Piu Chan & Shun Yu. (2013) Alpha-synuclein promotes early neurite outgrowth in cultured primary neurons. Journal of Neural Transmission 120:9, pages 1331-1343.
Crossref
Jonas Wietek, Ivan Haralampiev, Aouefa Amoussouvi, Andreas Herrmann & Martin Stöckl. (2013) Membrane bound α‐synuclein is fully embedded in the lipid bilayer while segments with higher flexibility remain. FEBS Letters 587:16, pages 2572-2577.
Crossref
Angélique Deleersnijder, Melanie Gerard, Zeger Debyser & Veerle Baekelandt. (2013) The remarkable conformational plasticity of alpha-synuclein: blessing or curse?. Trends in Molecular Medicine 19:6, pages 368-377.
Crossref
Maddalena Costanzo & Chiara Zurzolo. (2013) The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration. Biochemical Journal 452:1, pages 1-17.
Crossref
Kamil Tamiola & Frans A.A. Mulder. (2012) Using NMR chemical shifts to calculate the propensity for structural order and disorder in proteins. Biochemical Society Transactions 40:5, pages 1014-1020.
Crossref
Arianna Bellucci, Michela Zaltieri, Laura Navarria, Jessica Grigoletto, Cristina Missale & PierFranco Spano. (2012) From α-synuclein to synaptic dysfunctions: New insights into the pathophysiology of Parkinson's disease. Brain Research 1476, pages 183-202.
Crossref
H. Chadchankar, J. Ihalainen, H. Tanila & L. Yavich. (2012) Methylphenidate Modifies Overflow and Presynaptic Compartmentalization of Dopamine via an  -Synuclein-Dependent Mechanism. Journal of Pharmacology and Experimental Therapeutics 341:2, pages 484-492.
Crossref
Arianna Bellucci, Laura Navarria, Michela Zaltieri, Cristina Missale & PierFranco Spano. (2012) Alpha-synuclein synaptic pathology and its implications in the development of novel therapeutic approaches to cure Parkinson's disease. Brain Research 1432, pages 95-113.
Crossref
Arianna Bellucci, Laura Navarria, Elisa Falarti, Michela Zaltieri, Federica Bono, Ginetta Collo, Maria Grazia, Cristina Missale & PierFranco Spano. (2011) Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease. PLoS ONE 6:12, pages e27959.
Crossref
Furong Cheng, Giorgio Vivacqua & Shun Yu. (2011) The role of alpha-synuclein in neurotransmission and synaptic plasticity. Journal of Chemical Neuroanatomy 42:4, pages 242-248.
Crossref
Xabier Elcoroaristizabal Martín, Fernando Gómez Busto, M.C. González Fernández & y Marian M. de Pancorbo. (2011) Papel de la genética en la etiología de las sinucleinopatías. Revista Española de Geriatría y Gerontología 46, pages 3-11.
Crossref
Hedvig Welander, Sai Vineela Bontha, Thomas Näsström, Mikael Karlsson, Fredrik Nikolajeff, Karin Danzer, Marcus Kostka, Hannu Kalimo, Lars Lannfelt, Martin Ingelsson & Joakim Bergström. (2011) Gelsolin co-occurs with Lewy bodies in vivo and accelerates α-synuclein aggregation in vitro. Biochemical and Biophysical Research Communications 412:1, pages 32-38.
Crossref
Guylaine D’Amours, Geneviève Bureau, Marie-Josée Boily & Michel Cyr. (2011) Differential gene expression profiling in the mouse brain during motor skill learning: Focus on the striatum structure. Behavioural Brain Research 221:1, pages 108-117.
Crossref
Christina E. Khodr, Mohan K. Sapru, Jyothi Pedapati, Ye Han, Neva C. West, Adrian P. Kells, Krystof S. Bankiewicz & Martha C. Bohn. (2011) An alpha-synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson's disease, but displays toxicity in dopamine neurons. Brain Research 1395, pages 94-107.
Crossref
Robyn L. Croke, Sharadrao M. Patil, Jason Quevreaux, Debra A. Kendall & Andrei T. Alexandrescu. (2011) NMR determination of pKa values in α-synuclein. Protein Science 20:2, pages 256-269.
Crossref
Fiorella Malchiodi-Albedi, Silvia Paradisi, Andrea Matteucci, Claudio Frank & Marco Diociaiuti. (2011) Amyloid Oligomer Neurotoxicity, Calcium Dysregulation, and Lipid Rafts. International Journal of Alzheimer's Disease 2011, pages 1-17.
Crossref
Yofre Cabeza-Arvelaiz, Sheila M Fleming, Franziska Richter, Eliezer Masliah, Marie-Francoise Chesselet & Robert H Schiestl. (2011) Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons. Molecular Neurodegeneration 6:1, pages 83.
Crossref