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Communicative & Integrative Biology Volume 3, 2010 - Issue 4

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Direct internalization of cell-surface BST-2/tetherin by the HIV-1 accessory protein Vpu

Yukie Iwabu Department of Pathology; National Institute of Infectious Diseases; Japan

Hideaki Fujita Division of Pharmaceutical Cell Biology; Graduate School of Pharmaceutical Sciences; Kyushu University; Japan

Yoshitaka Tanaka Division of Pharmaceutical Cell Biology; Graduate School of Pharmaceutical Sciences; Kyushu University; Japan

Tetsutaro Sata Department of Pathology; National Institute of Infectious Diseases; Japan

Kenzo Tokunaga Department of Pathology; National Institute of Infectious Diseases; JapanCorrespondence[email protected]

Pages 366-369 | Received 29 Mar 2010, Accepted 29 Mar 2010, Published online: 01 Jul 2010

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https://doi.org/10.4161/cib.3.4.11971

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Weitong Yao, Klaus Strebel, Shoji Yamaoka & Takeshi Yoshida. (2022) Simian Immunodeficiency Virus SIVgsn-99CM71 Vpu Employs Different Amino Acids To Antagonize Human and Greater Spot-Nosed Monkey BST-2. Journal of Virology 96:4.
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Amukelani Marivate, Zikhona Njengele-Tetyana, Muhammad Qasim Fish & Salerwe Mosebi. (2021) Recombinant expression, purification, and characterization of full-length human BST-2 from Escherichia coli. Protein Expression and Purification 188, pages 105969.
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Weitong Yao, Takeshi Yoshida, Saki Hashimoto, Hiroaki Takeuchi, Klaus Strebel & Shoji Yamaoka. (2020) Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs. Journal of Virology 94:2.
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Viviana Simon, Nicolin Bloch & Nathaniel R Landau. (2015) Intrinsic host restrictions to HIV-1 and mechanisms of viral escape. Nature Immunology 16:6, pages 546-553.
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Kenzo TOKUNAGA. (2015) Identification of an antiviral host transmembrane protein MARCH8. Uirusu 65:2, pages 173-178.
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Xiaofei Jia, Erin Weber, Andrey Tokarev, Mary Lewinski, Maryan Rizk, Marissa Suarez, John Guatelli & Yong Xiong. (2014) Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1. eLife 3.
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Mingyu Lv, Yingzi Zhu, Jiawen Wang, Haihong Zhang, Xiaodan Wang, Tao Zuo, Donglai Liu, Jingyao Zhang, Jiaxin Wu, Wei Kong & Xianghui Yu. (2013) Purification of eukaryotic tetherin/Vpu proteins and detection of their interaction by ELISA. Protein Expression and Purification 91:2, pages 112-118.
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Yong-Hui Zheng, Kuan-Teh Jeang & Kenzo Tokunaga. (2012) Host restriction factors in retroviral infection: promises in virus-host interaction. Retrovirology 9:1.
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Mathieu Dubé, Catherine Paquay, Bibhuti Bhusan Roy, Mariana G. Bego, Johanne Mercier & Éric A. Cohen. (2011) HIV-1 Vpu Antagonizes BST-2 by Interfering Mainly with the Trafficking of Newly Synthesized BST-2 to the Cell Surface. Traffic 12:12, pages 1714-1729.
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Sarah Schmidt, Joëlle V. Fritz, Julia Bitzegeio, Oliver T. Fackler & Oliver T. Keppler. (2011) HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction. mBio 2:3.
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Katy Janvier, Annegret Pelchen–Matthews, Jean-Baptiste Renaud, Marina Caillet, Mark Marsh & Clarisse Berlioz-Torrent. (2011) The ESCRT-0 Component HRS is Required for HIV-1 Vpu-Mediated BST-2/Tetherin Down-Regulation. PLoS Pathogens 7:2, pages e1001265.
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Melissa Swiecki, Suzanne M. Scheaffer, Marc Allaire, Daved H. Fremont, Marco Colonna & Tom J. Brett. (2011) Structural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus Release. Journal of Biological Chemistry 286:4, pages 2987-2997.
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Direct internalization of cell-surface BST-2/tetherin by the HIV-1 accessory protein Vpu

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Direct internalization of cell-surface BST-2/tetherin by the HIV-1 accessory protein Vpu

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