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Hanxun Wang, Peilu Song, Yinli Gao, Lanlan Shen, Hanqin Xu, Jian Wang & Maosheng Cheng. (2021) Drug discovery targeting p21-activated kinase 4 (PAK4): a patent review. Expert Opinion on Therapeutic Patents 31:11, pages 977-987.
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Yi-Yang Wen, Jun-Nian Zheng & Dong-Sheng Pei. (2014) An oncogenic kinase: putting PAK5 forward. Expert Opinion on Therapeutic Targets 18:7, pages 807-815.
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Jeffrey Field & Ed Manser. (2012) The PAKs come of age. Cellular Logistics 2:2, pages 54-58.
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Zhuo-shen Zhao & Ed Manser. (2012) PAK family kinases. Cellular Logistics 2:2, pages 59-68.
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Articles from other publishers (28)
Md. Mozibullah & Md. Junaid. (2023) Biological role of the PAK4 signaling pathway: A prospective therapeutic target for multivarious cancers. Arabian Journal of Chemistry 16:1, pages 104438.
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Lauren Wegman-Points, Khaled Alganem, Ali Sajid Imami, Victoria Mathis, Justin Fortune Creeden, Robert McCullumsmith & Li-Lian Yuan. (2022) Subcellular partitioning of protein kinase activity revealed by functional kinome profiling. Scientific Reports 12:1.
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Kunjian Lei, Min Luo, Zewei Tu, Shigang Lv, Junzhe Liu, Chuandong Gong, Minhua Ye, Miaojing Wu, Yilei Sheng, Xiaoyan Long, Jingying Li, Xingen Zhu & Kai Huang. (2022) Comprehensive analysis of the prognostic implications and functional exploration of PAK gene family in human cancer. Cancer Cell International 22:1.
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Yaxing Wei, Wenjie Wu, Yanan Jiang, Hao Zhou, Yin Yu, Lili Zhao, Xiangyu Wu, Xuebo Lu, Qiang Yuan, Zitong Wang, Zigang Dong, Luyun He, Jimin Zhao & Kangdong Liu. (2021) Nuplazid suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting PAK4. British Journal of Cancer 126:7, pages 1037-1046.
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Susanna Cogo, Franz Y. Ho, Elena Tosoni, James E. Tomkins, Isabella Tessari, Lucia Iannotta, Thomas J. Montine, Claudia Manzoni, Patrick A. Lewis, Luigi Bubacco, Marie-Christine Chartier Harlin, Jean-Marc Taymans, Arjan Kortholt, Jeremy Nichols, Laura Cendron, Laura Civiero & Elisa Greggio. (2022) The Roc domain of LRRK2 as a hub for protein-protein interactions: a focus on PAK6 and its impact on RAB phosphorylation. Brain Research 1778, pages 147781.
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Lisa Uechi, Mahjoubeh Jalali, Jayson D. Wilbur, Jonathan L. French, N. L. Jumbe, Michael J. Meaney, Peter D. Gluckman, Neerja Karnani, Nikita A. Sakhanenko & David J. Galas. (2020) Complex genetic dependencies among growth and neurological phenotypes in healthy children: Towards deciphering developmental mechanisms. PLOS ONE 15:12, pages e0242684.
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Zlata Vershinin, Michal Feldman & Dan Levy. (2020) PAK4 methylation by the methyltransferase SETD6 attenuates cell adhesion. Scientific Reports 10:1.
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Mingliang Zhang, Xiaobao Fang, Cong Wang, Yi Hua, Chen Huang, Meng Wang, Lu Zhu, Zixu Wang, Yuhan Gao, Tianyi Zhang, Haichun Liu, Yanmin Zhang, Shuai Lu, Tao Lu, Yadong Chen & Hongmei Li. (2020) Design and synthesis of 1H-indazole-3-carboxamide derivatives as potent and selective PAK1 inhibitors with anti-tumour migration and invasion activities. European Journal of Medicinal Chemistry 203, pages 112517.
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Xiao-Peng Tian, Dan Xie, Wei-Juan Huang, Shu-Yun Ma, Liang Wang, Yan-Hui Liu, Xi Zhang, Hui-Qiang Huang, Tong-Yu Lin, Hui-Lan Rao, Mei Li, Fang Liu, Fen Zhang, Li-Ye Zhong, Li Liang, Xiao-Liang Lan, Juan Li, Bing Liao, Zhi-Hua Li, Qiong-Lan Tang, Qiong Liang, Chun-Kui Shao, Qiong-Li Zhai, Run-Fen Cheng, Qi Sun, Kun Ru, Xia Gu, Xi-Na Lin, Kun Yi, Yue-Rong Shuang, Xiao-Dong Chen, Wei Dong, Wei Sang, Cai Sun, Hui Liu, Zhi-Gang Zhu, Jun Rao, Qiao-Nan Guo, Ying Zhou, Xiang-Ling Meng, Yong Zhu, Chang-Lu Hu, Yi-Rong Jiang, Ying Zhang, Hong-Yi Gao, Wen-Jun He, Zhong-Jun Xia, Xue-Yi Pan, Hai Lan, Guo-Wei Li, Lu Liu, Hui-Zheng Bao, Li-Yan Song, Tie-Bang Kang & Qing-Qing Cai. (2020) A gene-expression-based signature predicts survival in adults with T-cell lymphoblastic lymphoma: a multicenter study. Leukemia 34:9, pages 2392-2404.
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Chan-Chan Gong, Tong-Tong Li & Dong-Sheng Pei. (2020) PAK6: a potential anti-cancer target. Brazilian Journal of Pharmaceutical Sciences 56.
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Chetan K. Rane & Audrey Minden. (2019) P21 activated kinase signaling in cancer. Seminars in Cancer Biology 54, pages 40-49.
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Laura Civiero, Susanna Cogo, Alice Biosa & Elisa Greggio. (2018) The role of LRRK2 in cytoskeletal dynamics. Biochemical Society Transactions 46:6, pages 1653-1663.
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Chetan K. Rane, Misaal Patel, Li Cai, William Senapedis, Erkan Baloglu & Audrey Minden. (2018) Decrypting the PAK4 transcriptome profile in mammary tumor forming cells using Next Generation Sequencing. Genomics 110:4, pages 248-256.
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Crossref
Jing Guo, Fan Zhao, Wenbo Yin, Mingyue Zhu, Chenzhou Hao, Yu Pang, Tianxiao Wu, Jian Wang, Dongmei Zhao, Haitao Li & Maosheng Cheng. (2018) Design, synthesis, structure-activity relationships study and X-ray crystallography of 3-substituted-indolin-2-one-5-carboxamide derivatives as PAK4 inhibitors. European Journal of Medicinal Chemistry 155, pages 197-209.
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Xiumei Zhang, Xia Zhang, Yang Li, Yangguang Shao, Jianying Xiao, Ge Zhu & Feng Li. (2017) PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth. Cell Death & Disease 8:5, pages e2820-e2820.
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Chetan Rane, William Senapedis, Erkan Baloglu, Yosef Landesman, Marsha Crochiere, Soumyasri Das-Gupta & Audrey Minden. (2017) A novel orally bioavailable compound KPT-9274 inhibits PAK4, and blocks triple negative breast cancer tumor growth. Scientific Reports 7:1.
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A.S. Azmi & P.A. Philip. 2017. Conquering RAS. Conquering RAS
251
270
.
Remya Raja, Nandini A. Sahasrabuddhe, Aneesha Radhakrishnan, Nazia Syed, Hitendra S. Solanki, Vinuth N. Puttamallesh, Sai A. Balaji, Vishalakshi Nanjappa, Keshava K. Datta, Niraj Babu, Santosh Renuse, Arun H. Patil, Evgeny Izumchenko, T.S. Keshava Prasad, Xiaofei Chang, Annapoorni Rangarajan, David Sidransky, Akhilesh Pandey, Harsha Gowda & Aditi Chatterjee. (2016) Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells. Oncotarget 7:38, pages 61229-61245.
Crossref
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Kai Huang, Gang Chen, Jingfang Luo, Youyuan Zhang & Guoxiong Xu. (2014) Clinicopathological and cellular signature of PAK1 in human bladder cancer. Tumor Biology 36:4, pages 2359-2368.
Crossref
Crossref
Joachim Rudolph, James J. Crawford, Klaus P. Hoeflich & Weiru Wang. (2014) Inhibitors of p21-Activated Kinases (PAKs). Journal of Medicinal Chemistry 58:1, pages 111-129.
Crossref
Crossref
Jian Chen, Huijun Lu, Dongwang Yan, Feifei Cui, Xiaoliang Wang, Fudong Yu, Yingming Xue, Xiaodong Feng, Jingtao Wang, Xiao Wang, Tao Jiang, Meng Zhang, Senlin Zhao, Yang Yu, Huamei Tang & Zhihai Peng. (2014) PAK6 increase chemoresistance and is a prognostic marker for stage II and III colon cancer patients undergoing 5-FU based chemotherapy. Oncotarget 6:1, pages 355-367.
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Crossref
Orsolya Kiss, Anna-Mária Tőkés, Sándor Spisák, Anna Szilágyi, Norbert Lippai, Borbála Székely, A. Marcell Szász & Janina Kulka. (2014) Breast- and Salivary Gland-Derived Adenoid Cystic Carcinomas: Potential Post-Transcriptional Divergencies. A Pilot Study Based on miRNA Expression Profiling of Four Cases and Review of the Potential Relevance of the Findings. Pathology & Oncology Research 21:1, pages 29-44.
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André P. Koth, Bruno R. Oliveira, Gustavo M. Parfitt, Juliana de Quadros Buonocore & Daniela M. Barros. (2014) Participation of group I p21-activated kinases in neuroplasticity. Journal of Physiology-Paris 108:4-6, pages 270-277.
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C Wang, Y Li, H Zhang, F Liu, Z Cheng, D Wang, G Wang, H Xu, Y Zhao, L Cao & F Li. (2013) Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis. Oncogene 33:26, pages 3473-3484.
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Rui-Juan Li, Jian Wang, Zhen Xu, Wan-Xu Huang, Jia Li, Sheng-Fei Jin, Dong-Mei Zhao & Mao-Sheng Cheng. (2014) Computational Insight into p21-Activated Kinase 4 Inhibition: A Combined Ligand- and Structure-Based Approach. ChemMedChem 9:5, pages 1012-1022.
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Steven T. Staben, Jianwen A. Feng, Karen Lyle, Marcia Belvin, Jason Boggs, Jason D. Burch, Ching-ching Chua, Haifeng Cui, Antonio G. DiPasquale, Lori S. Friedman, Christopher Heise, Hartmut Koeppen, Adrian Kotey, Robert Mintzer, Angela Oh, David Allen Roberts, Lionel Rouge, Joachim Rudolph, Christine Tam, Weiru Wang, Yisong Xiao, Amy Young, Yamin Zhang & Klaus P. Hoeflich. (2014) Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors. Journal of Medicinal Chemistry 57:3, pages 1033-1045.
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Helen King, Nicole S. Nicholas & Claire M. Wells. 2014.
347
387
.
Marianne van Dijk, Sara A. Göransson & Staffan Strömblad. (2013) Cell to extracellular matrix interactions and their reciprocal nature in cancer. Experimental Cell Research 319:11, pages 1663-1670.
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