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Epigenetics Volume 8, 2013 - Issue 2
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Brief Report

Breaking through an epigenetic wall

Re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors

Karla Juárez-Moreno Department of Pharmacology; University of North Carolina School of Medicine; Chapel Hill, NC USA; Centro de Nanociencias y Nanotecnologia; UNAM; Ensenada, B.C. México
,
Rafaela Erices Department of Pharmacology; University of North Carolina School of Medicine; Chapel Hill, NC USA; Biomedical Research Consortium Chile; Pontificia Universidad Católica de Chile; Santiago, Chile; Universidad Nacional Andrés Bello; Santiago, Chile
,
Adriana S. Beltran Department of Pharmacology; University of North Carolina School of Medicine; Chapel Hill, NC USA
,
Sabine Stolzenburg Department of Pharmacology; University of North Carolina School of Medicine; Chapel Hill, NC USA; School of Anatomy, Physiology and Human Biology; The University of Western Australia; Crawley, WA Australia
,
Mauricio Cuello-Fredes Laboratorio de Obstetricia y Ginecología; Centro de Investigaciones Médicas; Pontificia Universidad Católica de Chile; Santiago, Chile
,
Gareth I. Owen Biomedical Research Consortium Chile; Pontificia Universidad Católica de Chile; Santiago, Chile
,
Haili Qian Department of Pharmacology; University of North Carolina School of Medicine; Chapel Hill, NC USA; State Key Laboratory of Molecular Oncology; Chinese Academy of Medical Sciences; Beijing, P.R. China
&
Pilar Blancafort Department of Pharmacology; University of North Carolina School of Medicine; Chapel Hill, NC USA; School of Anatomy, Physiology and Human Biology; The University of Western Australia; Crawley, WA AustraliaCorrespondence[email protected]
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Pages 164-176 | Received 08 Nov 2012, Accepted 04 Jan 2013, Published online: 11 Jan 2013

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Mariana Brütt Pacheco, Vânia Camilo, Rui Henrique & Carmen Jerónimo. (2022) Epigenetic Editing in Prostate Cancer: Challenges and Opportunities. Epigenetics 17:5, pages 564-588.
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Gurbachan S. Miglani, Anroop Kaur & Lovepreet Kaur. (2020) Plant gene expression control using genome- and epigenome-editing technologies. Journal of Crop Improvement 34:1, pages 1-63.
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Articles from other publishers (15)

Letizia Fontana, Zoe Alahouzou, Annarita Miccio & Panagiotis Antoniou. (2023) Epigenetic Regulation of β-Globin Genes and the Potential to Treat Hemoglobinopathies through Epigenome Editing. Genes 14:3, pages 577.
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Agustin Sgro & Pilar Blancafort. (2020) Epigenome engineering: new technologies for precision medicine. Nucleic Acids Research 48:22, pages 12453-12482.
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Charlene Babra Waryah, Colette Moses, Mahira Arooj & Pilar Blancafort. 2018. Epigenome Editing. Epigenome Editing 19 63 .
Vinita Periwal. (2016) A comprehensive overview of computational resources to aid in precision genome editing with engineered nucleases. Briefings in Bioinformatics, pages bbw052.
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Yu Fan, Qian Zhan, Hongying Xu, Lili Li, Chen Li, Qian Xiao, Shili Xiang, Tianli Hui, Tingxiu Xiang & Guosheng Ren. (2016) Epigenetic identification of ZNF545 as a functional tumor suppressor in multiple myeloma via activation of p53 signaling pathway. Biochemical and Biophysical Research Communications 474:4, pages 660-666.
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Mesut Muyan, Gizem Güpür, Pelin Yaşar, Gamze Ayaz, Sırma Damla User, Hasan Hüseyin Kazan & Yanfang Huang. (2015) Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators. PLOS ONE 10:8, pages e0136423.
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Monique G.P. van der Wijst, Christian Huisman, Archibold Mposhi, Gerard Roelfes & Marianne G. Rots. (2015) Targeting Nrf2 in healthy and malignant ovarian epithelial cells: Protection versus promotion. Molecular Oncology 9:7, pages 1259-1273.
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E A Vasileva, O U Shuvalov, A V Garabadgiu, G Melino & N A Barlev. (2015) Genome-editing tools for stem cell biology. Cell Death & Disease 6:7, pages e1831-e1831.
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Fahimeh Falahi, Agustin Sgro & Pilar Blancafort. (2015) Epigenome Engineering in Cancer: Fairytale or a Realistic Path to the Clinic?. Frontiers in Oncology 5.
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Ritu Kushwaha, Nirmala Jagadish, Manjunath Kustagi, Mark J. Tomishima, Geetu Mendiratta, Mukesh Bansal, Hyunjae R. Kim, Pavel Sumazin, Mariano J. Alvarez, Celine Lefebvre, Patricia Villagrasa-Gonzalez, Agnes Viale, James E. Korkola, Jane Houldsworth, Darren R. Feldman, George J. Bosl, Andrea Califano & R. S. K. Chaganti. (2015) Interrogation of a Context-Specific Transcription Factor Network Identifies Novel Regulators of Pluripotency. Stem Cells 33:2, pages 367-377.
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Matthew R. Grimmer, Sabine Stolzenburg, Ethan Ford, Ryan Lister, Pilar Blancafort & Peggy J. Farnham. (2014) Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation. Nucleic Acids Research 42:16, pages 10856-10868.
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Qingzhou Ji, Ashley L. Fischer, Clyde R. Brown, Erik R. Eastlund, Tamar Dvash, Bonan Zhong, Mark A. Gerber, Ian Lyons, Scott W. Knight & Carol A. Kreader. (2014) Engineered zinc-finger transcription factors activate OCT4 (POU5F1), SOX2, KLF4, c-MYC (MYC) and miR302/367. Nucleic Acids Research 42:10, pages 6158-6167.
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Juan Carlos Mellídez Barroso & Maria C. Santos. 2014. Stem Cells in Cancer: Should We Believe or Not?. Stem Cells in Cancer: Should We Believe or Not? 263 290 .
Fahimeh Falahi, Christian Huisman, Hinke G. Kazemier, Pieter van der Vlies, Klaas Kok, Geke A.P. Hospers & Marianne G. Rots. (2013) Towards Sustained Silencing of HER2/neu in Cancer By Epigenetic Editing. Molecular Cancer Research 11:9, pages 1029-1039.
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Xuefei Gao, Jian Yang, Jason C.H. Tsang, Jolene Ooi, Donghai Wu & Pentao Liu. (2013) Reprogramming to Pluripotency Using Designer TALE Transcription Factors Targeting Enhancers. Stem Cell Reports 1:2, pages 183-197.
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