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Epigenetics Volume 8, 2013 - Issue 6
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Research Paper

Zebularine partially reverses GST methylation in prostate cancer cells and restores sensitivity to the DNA minor groove binder brostallicin

Maria Antonietta Sabatino Laboratory of Molecular Pharmacology; Department of Oncology; IRCCS—Istituto di Ricerche Farmacologiche Mario Negri; Milan, Italy
,
Cristina Geroni Pharmacia SpA; Milan, Italy
,
Monica Ganzinelli Laboratory of Molecular Pharmacology; Department of Oncology; IRCCS—Istituto di Ricerche Farmacologiche Mario Negri; Milan, Italy
,
Roberta Ceruti Laboratory of Molecular Pharmacology; Department of Oncology; IRCCS—Istituto di Ricerche Farmacologiche Mario Negri; Milan, Italy
&
Massimo Broggini Laboratory of Molecular Pharmacology; Department of Oncology; IRCCS—Istituto di Ricerche Farmacologiche Mario Negri; Milan, ItalyCorrespondence[email protected]
Pages 656-665 | Received 12 Feb 2013, Accepted 03 May 2013, Published online: 14 Jun 2013

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Xu Hao, Yuanyuan Li, Jialu Bian, Ying Zhang, Shiyu He, Feng Yu, Yufei Feng & Lin Huang. (2022) Impact of DNA methylation on ADME gene expression, drug disposition, and efficacy. Drug Metabolism Reviews 54:2, pages 194-206.
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Swagata Adhikari, Apoorva Bhattacharya, Santanu Adhikary, Vipin Singh, Shrikanth S. GadadSiddhartha Roy & Chandrima Das. (2022) The paradigm of drug resistance in cancer: an epigenetic perspective. Bioscience Reports 42:4.
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Rakesh Srivastava & Niraj Lodhi. (2022) DNA Methylation Malleability and Dysregulation in Cancer Progression: Understanding the Role of PARP1. Biomolecules 12:3, pages 417.
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Asia C. Jordan, M. Prencipe, Romina Silva, William M. Gallagher & A.S. Perry. 2022. Epigenetics in Precision Medicine. Epigenetics in Precision Medicine 69 108 .
Anthony Quagliano, Anilkumar Gopalakrishnapillai & Sonali P. Barwe. (2020) Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer. Frontiers in Oncology 10.
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Khushboo Agrawal, Viswanath Das, Pankhuri Vyas & Marián Hajdúch. (2018) Nucleosidic DNA demethylating epigenetic drugs – A comprehensive review from discovery to clinic. Pharmacology & Therapeutics 188, pages 45-79.
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Li Chen, Yanyan Miao, Mengni Liu, Yanru Zeng, Zijun Gao, Di Peng, Bosu Hu, Xu Li, Yueyuan Zheng, Yu Xue, Zhixiang Zuo, Yubin Xie & Jian Ren. (2018) Pan-Cancer Analysis Reveals the Functional Importance of Protein Lysine Modification in Cancer Development. Frontiers in Genetics 9.
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Ângela Marques-Magalhães, Inês Graça, Rui Henrique & Carmen Jerónimo. (2018) Targeting DNA Methyltranferases in Urological Tumors. Frontiers in Pharmacology 9.
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Michal Chovanec, Fadi Taza, Maitri Kalra, Noah Hahn, Kenneth P. Nephew, Michael J. Spinella & Costantine Albany. (2017) Incorporating DNA Methyltransferase Inhibitors (DNMTis) in the Treatment of Genitourinary Malignancies: A Systematic Review. Targeted Oncology 13:1, pages 49-60.
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Inês Graça, Eva Pereira-Silva, Rui Henrique, Graham Packham, Simon J. Crabb & Carmen Jerónimo. (2016) Epigenetic modulators as therapeutic targets in prostate cancer. Clinical Epigenetics 8:1.
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Jocelyn Ang, Lisa Yun Song, Sara D'Souza, Irene L. Hong, Rohan Luhar, Madeline Yung & Jeffrey H. Miller. (2016) Mutagen Synergy: Hypermutability Generated by Specific Pairs of Base Analogs. Journal of Bacteriology 198:20, pages 2776-2783.
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Michel Neidhart. 2016. DNA Methylation and Complex Human Disease. DNA Methylation and Complex Human Disease 161 175 .
Bridget M Nugent, Christopher L Wright, Amol C Shetty, Georgia E Hodes, Kathryn M Lenz, Anup Mahurkar, Scott J Russo, Scott E Devine & Margaret M McCarthy. (2015) Brain feminization requires active repression of masculinization via DNA methylation. Nature Neuroscience 18:5, pages 690-697.
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Hai-long Ma, Cong Yu, Ying Liu, Yi-ran Tan, Jin-ke Qiao, Xi Yang, Li-zhen Wang, Jiang Li, Qiong Chen, Fu-xiang Chen, Zhi-yuan Zhang & Lai-ping Zhong. (2015) Decreased expression of glutathione S-transferase pi correlates with poorly differentiated grade in patients with oral squamous cell carcinoma. Journal of Oral Pathology & Medicine 44:3, pages 193-200.
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Emma E. Ramsay & Pierre J. Dilda. (2014) Glutathione S-conjugates as prodrugs to target drug-resistant tumors. Frontiers in Pharmacology 5.
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Sahar Houshdaran, Zara Zelenko, Juan C. Irwin & Linda C. Giudice. (2014) Human Endometrial DNA Methylome Is Cycle-Dependent and Is Associated With Gene Expression Regulation. Molecular Endocrinology 28:7, pages 1118-1135.
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Ilaria Naldi, Monia Taranta, Lisa Gherardini, Gualtiero Pelosi, Federica Viglione, Settimio Grimaldi, Luca Pani & Caterina Cinti. (2014) Novel Epigenetic Target Therapy for Prostate Cancer: A Preclinical Study. PLoS ONE 9:5, pages e98101.
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