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Research Paper

Immunotherapy in new pre-clinical models of HPV-associated oral cancers

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Pages 534-543 | Received 10 Oct 2012, Accepted 23 Oct 2012, Published online: 07 Jan 2013

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Ziva Modic, Maja Cemazar, Bostjan Markelc, Andrej Cör, Gregor Sersa, Simona Kranjc Brezar & Tanja Jesenko. (2023) HPV-positive murine oral squamous cell carcinoma: development and characterization of a new mouse tumor model for immunological studies. Journal of Translational Medicine 21:1.
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Aric Huang, Chad Groer, Ruolin Lu, M. Laird Forrest, J. Daniel Griffin & Cory J. Berkland. (2022) Glatiramer Acetate Complexed with CpG as Intratumoral Immunotherapy in Combination with Anti-PD-1. Molecular Pharmaceutics 19:11, pages 4357-4369.
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D. V. Avdoshina, A. S. Kondrashova, M. G. Belikova & E. O. Bayurova. (2022) Murine Models of Chronic Viral Infections and Associated Cancers. Molecular Biology 56:5, pages 649-667.
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Maria G. Isaguliants, Ivan Trotsenko & Franco M. Buonaguro. (2022) An overview of “Chronic viral infection and cancer, openings for vaccines” virtual symposium of the TechVac Network - December 16-17, 2021. Infectious Agents and Cancer 17:S2.
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Francesca Paolini, Carla Amici, Mariantonia Carosi, Claudia Bonomo, Paola Di Bonito, Aldo Venuti & Luisa Accardi. (2021) Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors. Journal of Experimental & Clinical Cancer Research 40:1.
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Talia R. Henkle, Brandon Lam, Yu Jui Kung, John Lin, Ssu-Hsueh Tseng, Louise Ferrall, Deyin Xing, Chien-Fu Hung & T.-C. Wu. (2021) Development of a Novel Mouse Model of Spontaneous High-Risk HPVE6/E7–Expressing Carcinoma in the Cervicovaginal Tract. Cancer Research 81:17, pages 4560-4569.
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Melissa M. Pressnall, Aric Huang, Chad E. Groer, Sebastian G. Huayamares, M. Laird Forrest & Cory J. Berkland. (2021) Glatiramer acetate enhances tumor retention and innate activation of immunostimulants. International Journal of Pharmaceutics 605, pages 120812.
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Pierre Haen, Lydie Crescence, Diane Mege, Alexandre Altié, Christophe Dubois & Laurence Panicot-Dubois. (2021) Oral Squamous Cell Carcinoma Is Associated with a Low Thrombosis Risk Due to Storage Pool Deficiency in Platelets. Biomedicines 9:3, pages 228.
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Sebastian G. Huayamares, Jimmy Y. Song, Aric Huang, Samuel R. Crowl, Chad E. Groer, M. Laird Forrest & Cory J. Berkland. (2020) Constructing a Biomaterial to Simulate Extracellular Drug Transport in Solid Tumors. Macromolecular Bioscience 20:12, pages 2000251.
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Chad Groer, Ti Zhang, Ruolin Lu, Shuang Cai, Derek Mull, Aric Huang, Melanie Forrest, Cory Berkland, Daniel Aires & Marcus Laird Forrest. (2020) Intratumoral Cancer Chemotherapy with a Carrier-Based Immunogenic Cell-Death Eliciting Platinum (IV) Agent. Molecular Pharmaceutics 17:11, pages 4334-4345.
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Rosella Franconi, Silvia Massa, Francesca Paolini, Patrizia Vici & Aldo Venuti. (2020) Plant-Derived Natural Compounds in Genetic Vaccination and Therapy for HPV-Associated Cancers. Cancers 12:11, pages 3101.
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Hui Li, Hoi-Lam Ngan, Yuchen Liu, Helen Hoi Yin Chan, Peony Hiu Yan Poon, Chun Kit Yeung, Yibing Peng, Wai Yip Lam, Benjamin Xiaoyi Li, Yukai He & Vivian Wai Yan Lui. (2020) Comprehensive Exome Analysis of Immunocompetent Metastatic Head and Neck Cancer Models Reveals Patient Relevant Landscapes. Cancers 12:10, pages 2935.
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Samantha Zottnick, Alessa L. Voß & Angelika B. Riemer. (2020) Inducing Immunity Where It Matters: Orthotopic HPV Tumor Models and Therapeutic Vaccinations. Frontiers in Immunology 11.
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Sangwoo S. Kim, Sarek Shen, Sayuri Miyauchi, P. Dominick Sanders, Ida Franiak-Pietryga, Loren Mell, J. Silvio Gutkind, Ezra E.W. Cohen, Joseph A. Califano & Andrew B. Sharabi. (2020) B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade. Clinical Cancer Research 26:13, pages 3345-3359.
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Qiang Li, Heng Dong, Guangwen Yang, Yuxian Song, Yongbin Mou & Yanhong Ni. (2020) Mouse Tumor-Bearing Models as Preclinical Study Platforms for Oral Squamous Cell Carcinoma. Frontiers in Oncology 10.
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Sayuri Miyauchi, P. Dominick Sanders, Kripa Guram, Sangwoo S. Kim, Francesca Paolini, Aldo Venuti, Ezra E.W. Cohen, J. Silvio Gutkind, Joseph A. Califano & Andrew B. Sharabi. (2020) HPV16 E5 Mediates Resistance to PD-L1 Blockade and Can Be Targeted with Rimantadine in Head and Neck Cancer. Cancer Research 80:4, pages 732-746.
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Ruolin Lu, Chad Groer, Peter A. Kleindl, K. Ryan Moulder, Aric Huang, Jordan R. Hunt, Shuang Cai, Daniel J. Aires, Cory Berkland & M. Laird Forrest. (2019) Formulation and preclinical evaluation of a toll-like receptor 7/8 agonist as an anti-tumoral immunomodulator. Journal of Controlled Release 306, pages 165-176.
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Juan José Mora Román, Miguel Del Campo, Javiera Villar, Francesca Paolini, Gianfranca Curzio, Aldo Venuti, Lilian Jara, Jorge Ferreira, Paola Murgas, Alvaro Lladser, Augusto Manubens & María Inés Becker. (2019) Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer. Journal of Immunology Research 2019, pages 1-19.
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Yi-Hsin Lin, Ming-Chieh Yang, Ssu-Hsueh Tseng, Rosie Jiang, Andrew Yang, Emily Farmer, Shiwen Peng, Talia Henkle, Yung-Nien Chang, Chien-Fu Hung & T.-C. Wu. (2018) Integration of Oncogenes via Sleeping Beauty as a Mouse Model of HPV16+ Oral Tumors and Immunologic Control. Cancer Immunology Research 6:3, pages 305-319.
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Carla Amici, Michela Visintin, Francesca Verachi, Francesca Paolini, Zulema Percario, Paola Di Bonito, Angela Mandarino, Elisabetta Affabris, Aldo Venuti & Luisa Accardi. (2016) A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models. Oncotarget 7:13, pages 15539-15553.
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C. L. Zuur, A. J. C. Dohmen, Michiel W. van den Brekel, Xiao-Jing Wang & Stephen Malkosky. 2016. Head and Neck Cancer. Head and Neck Cancer 205 213 .
Aldo Venuti, Gianfranca Curzio, Luciano Mariani & Francesca Paolini. (2015) Immunotherapy of HPV-associated cancer: DNA/plant-derived vaccines and new orthotopic mouse models. Cancer Immunology, Immunotherapy 64:10, pages 1329-1338.
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Mauro Morgenfeld, Ezequiel Lentz, María Eugenia Segretin, E. Federico Alfano & Fernando Bravo-Almonacid. (2014) Translational Fusion and Redirection to Thylakoid Lumen as Strategies to Enhance Accumulation of Human Papillomavirus E7 Antigen in Tobacco Chloroplasts. Molecular Biotechnology 56:11, pages 1021-1031.
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Luisa Accardi, Francesca Paolini, Angela Mandarino, Zulema Percario, Paola Di Bonito, Valentina Di Carlo, Elisabetta Affabris, Colomba Giorgi, Carla Amici & Aldo Venuti. (2014) In vivo antitumor effect of an intracellular single-chain antibody fragment against the E7 oncoprotein of human papillomavirus 16 . International Journal of Cancer 134:11, pages 2742-2747.
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