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Special Focus Review

Whole parasite blood stage malaria vaccines: A convergence of evidence

Pages 114-123 | Published online: 01 Jan 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Michael F. Good & Louis H. Miller. (2018) Interpreting challenge data from early phase malaria blood stage vaccine trials. Expert Review of Vaccines 17:3, pages 189-196.
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Susanne H Sheehy, Alexander D Douglas & Simon J Draper. (2013) Challenges of assessing the clinical efficacy of asexual blood-stage malaria vaccines. Human Vaccines & Immunotherapeutics 9:9, pages 1831-1840.
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Ruth D. Ellis, Issaka Sagara, Ogobara Doumbo & Yimin Wu. (2010) Blood stage vaccines for Plasmodium falciparum. Human Vaccines 6:8, pages 627-634.
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Cevayir Coban, Toshihiro Horii, Shizuo Akira & Ken J Ishii. (2010) TLR9 and endogenous adjuvants of the whole blood-stage malaria vaccine. Expert Review of Vaccines 9:7, pages 775-784.
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Articles from other publishers (38)

Rebecca Webster, Silvana Sekuloski, Anand Odedra, Stephen Woolley, Helen Jennings, Fiona Amante, Katharine R. Trenholme, Julie Healer, Alan F. Cowman, Emily M. Eriksson, Priyanka Sathe, Jocelyn Penington, Adam J. Blanch, Matthew W. A. Dixon, Leann Tilley, Michael F. Duffy, Alister Craig, Janet Storm, Jo-Anne Chan, Krystal Evans, Anthony T. Papenfuss, Louis Schofield, Paul Griffin, Bridget E. Barber, Dean Andrew, Michelle J. Boyle, Fabian de Labastida Rivera, Christian Engwerda & James S. McCarthy. (2021) Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine. BMC Medicine 19:1.
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Michael F. Good & Danielle I. Stanisic. (2019) Whole parasite vaccines for the asexual blood stages of Plasmodium . Immunological Reviews 293:1, pages 270-282.
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Anudeep K. Narula, Chandra S. Azad & Lalit M. Nainwal. (2019) New dimensions in the field of antimalarial research against malaria resurgence. European Journal of Medicinal Chemistry 181, pages 111353.
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Sara E. White, Steven A. Harvey, Graciela Meza, Alejandro Llanos, Mitchel Guzman, Dionicia Gamboa & Joseph M. Vinetz. (2018) Acceptability of a herd immunity-focused, transmission-blocking malaria vaccine in malaria-endemic communities in the Peruvian Amazon: an exploratory study. Malaria Journal 17:1.
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Leanne M. Low, Danielle I. Stanisic & Michael F. Good. (2018) Exploiting the apicoplast: apicoplast-targeting drugs and malaria vaccine development. Microbes and Infection 20:9-10, pages 477-483.
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K. A. Sala, F. Angrisano, D. F. Da, I. J. Taylor, T. S. Churcher & A. M. Blagborough. (2018) Immunization with Transgenic Rodent Malaria Parasites Expressing Pfs25 Induces Potent Transmission-Blocking Activity. Scientific Reports 8:1.
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W. Ripley Ballou & Johan Vekemans. 2018. Plotkin's Vaccines. Plotkin's Vaccines 561 566.e3 .
Satarudra Prakash Singh, Deeksha Srivastava & Bhartendu Nath Mishra. (2017) Genome-wide identification of novel vaccine candidates for Plasmodium falciparum malaria using integrative bioinformatics approaches. 3 Biotech 7:5.
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James M. BurnsJr.Jr., Kazutoyo Miura, JoAnn Sullivan, Carole A. Long & John W. Barnwell. (2016) Immunogenicity of a chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus monkeys. Malaria Journal 15:1.
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KARINA P. DE SOUSA & DENISE L. DOOLAN. (2016) Immunomics: a 21st century approach to vaccine development for complex pathogens. Parasitology 143:2, pages 236-244.
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Danielle I. Stanisic & Michael F. Good. (2015) Whole organism blood stage vaccines against malaria. Vaccine 33:52, pages 7469-7475.
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David J. Conway. (2015) Paths to a malaria vaccine illuminated by parasite genomics. Trends in Genetics 31:2, pages 97-107.
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Else M. Bijker, Anne C. Teirlinck, Remko Schats, Geert-Jan van Gemert, Marga van de Vegte-Bolmer, Lisette van Lieshout, Joanna IntHout, Cornelus C. Hermsen, Anja Scholzen, Leo G. Visser & Robert W. Sauerwein. (2014) Cytotoxic Markers Associate With Protection Against Malaria in Human Volunteers Immunized With Plasmodium falciparum Sporozoites . Journal of Infectious Diseases 210:10, pages 1605-1615.
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Agnieszka A. Religa, Jai Ramesar, Chris J. Janse, Artur Scherf & Andrew P. Waters. (2014) P. berghei Telomerase Subunit TERT is Essential for Parasite Survival. PLoS ONE 9:10, pages e108930.
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Peter D. Crompton, Jacqueline Moebius, Silvia Portugal, Michael Waisberg, Geoffrey Hart, Lindsey S. GarverLouis H. MillerCarolina Barillas-MurySusan K. Pierce. (2014) Malaria Immunity in Man and Mosquito: Insights into Unsolved Mysteries of a Deadly Infectious Disease. Annual Review of Immunology 32:1, pages 157-187.
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J. B. de Souza. (2014) Protective immunity against malaria after vaccination. Parasite Immunology 36:3, pages 131-139.
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Danielle I. Stanisic, Alyssa E. Barry & Michael F. Good. (2013) Escaping the immune system: How the malaria parasite makes vaccine development a challenge. Trends in Parasitology 29:12, pages 612-622.
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Michael F. Good, Jennifer M. Reiman, I. Bibiana Rodriguez, Koichi Ito, Stephanie K. Yanow, Ibrahim M. El-Deeb, Michael R. Batzloff, Danielle I. Stanisic, Christian Engwerda, Terry Spithill, Stephen L. Hoffman, Moses Lee & Virginia McPhun. (2013) Cross-species malaria immunity induced by chemically attenuated parasites. Journal of Clinical Investigation 123:8, pages 3353-3362.
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Anna L. Goodman, Emily K. Forbes, Andrew R. Williams, Alexander D. Douglas, Simone C. de Cassan, Karolis Bauza, Sumi Biswas, Matthew D. J. Dicks, David Llewellyn, Anne C. Moore, Chris J. Janse, Blandine M. Franke-Fayard, Sarah C. Gilbert, Adrian V. S. Hill, Richard J. Pleass & Simon J. Draper. (2013) The utility of Plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment. Scientific Reports 3:1.
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W. Ripley Ballou & Joe Cohen. 2013. Vaccines. Vaccines 1133 1137 .
Christopher V. Plowe. 2013. Infectious Diseases. Infectious Diseases 171 197 .
Alberto Moreno. 2012. Immunity to Parasitic Infection. Immunity to Parasitic Infection 417 430 .
Megumi Inoue, Jianxia Tang, Mana Miyakoda, Osamu Kaneko, Katsuyuki Yui & Richard Culleton. (2012) The species specificity of immunity generated by live whole organism immunisation with erythrocytic and pre-erythrocytic stages of rodent malaria parasites and implications for vaccine development. International Journal for Parasitology 42:9, pages 859-870.
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Sumi Biswas, Alexandra J. Spencer, Emily K. Forbes, Sarah C. Gilbert, Anthony A. Holder, Adrian V. S. Hill & Simon J. Draper. (2012) Recombinant Viral-Vectored Vaccines Expressing Plasmodium chabaudi AS Apical Membrane Antigen 1: Mechanisms of Vaccine-Induced Blood-Stage Protection . The Journal of Immunology 188:10, pages 5041-5053.
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Krystelle Nganou-Makamdop, Geert-Jan van Gemert, Theo Arens, Cornelus C. Hermsen & Robert W. Sauerwein. (2012) Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFN? Responses of Hepatic CD8+ Memory T Cells. PLoS ONE 7:5, pages e36508.
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Yanhui Zhang, Yanwei Qi, Jian Li, Shengfa Liu, Lingxian Hong, Tianlong Lin, Carole Long & Xin-zhuan Su. (2011) A new malaria antigen produces partial protection against Plasmodium yoelii challenge. Parasitology Research 110:4, pages 1337-1345.
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Mahamadou A. TheraChristopher V. Plowe. (2012) Vaccines for Malaria: How Close Are We?. Annual Review of Medicine 63:1, pages 345-357.
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B.M. Greenwood & G.A.T. Targett. (2011) Malaria vaccines and the new malaria agenda. Clinical Microbiology and Infection 17:11, pages 1600-1607.
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Adrian V. S. Hill. (2011) Vaccines against malaria. Philosophical Transactions of the Royal Society B: Biological Sciences 366:1579, pages 2806-2814.
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Geoffrey Ian McFadden. (2010) The apicoplast. Protoplasma 248:4, pages 641-650.
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Noel J. Gerald, Victoria Majam, Babita Mahajan, Yukiko Kozakai & Sanjai Kumar. (2011) Protection from Experimental Cerebral Malaria with a Single Dose of Radiation-Attenuated, Blood-Stage Plasmodium berghei Parasites. PLoS ONE 6:9, pages e24398.
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Steffen Borrmann & Kai Matuschewski. (2011) Targeting Plasmodium liver stages: better late than never. Trends in Molecular Medicine 17:9, pages 527-536.
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Ellen Yeh & Joseph L. DeRisi. (2011) Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum. PLoS Biology 9:8, pages e1001138.
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Robin F. Anders. (2011) The case for a subunit vaccine against malaria. Trends in Parasitology 27:8, pages 330-334.
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Michael F. Good. (2011) A whole parasite vaccine to control the blood stages of Plasmodium – the case for lateral thinking. Trends in Parasitology 27:8, pages 335-340.
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Denise L. Doolan. (2011) Plasmodium immunomics. International Journal for Parasitology 41:1, pages 3-20.
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Carole A. Long & Fidel P. Zavala. 2010. The Immune Response to Infection. The Immune Response to Infection 587 597 .
Ahmed S. I. Aly, Megan J. Downie, Choukri Ben Mamoun & Stefan H. I. Kappe. (2010) Subpatent infection with nucleoside transporter 1-deficient Plasmodium blood stage parasites confers sterile protection against lethal malaria in mice. Cellular Microbiology 12:7, pages 930-938.
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