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Special Focus Review

Recombinant protein vaccines against the asexual blood-stages of Plasmodium falciparum

Pages 39-53 | Published online: 01 Jan 2010

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Mohan Bairwa, Meena Rajput, Pardeep Khanna, Ravi Rohilla, Ramesh Verma & Sumit Chawla. (2012) Malaria vaccine. Human Vaccines & Immunotherapeutics 8:6, pages 819-822.
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Christopher J.A. Duncan, Adrian V.S. Hill & Ruth D. Ellis. (2012) Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy?. Human Vaccines & Immunotherapeutics 8:6, pages 706-714.
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Articles from other publishers (43)

Amal A. El-Moamly & Mohamed A. El-Sweify. (2023) Malaria vaccines: the 60-year journey of hope and final success—lessons learned and future prospects. Tropical Medicine and Health 51:1.
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Sreedam C. Das, Jason D. Price, Katharine Gosling, Nicola MacLennan, Ricardo Ataíde, Jeffrey Seow, Vashti Irani, Ines I. Atmosukarto, Robin F. Anders, Jack S. Richards, Christopher A. MacRaild & Raymond S. Norton. (2021) Liposome engraftment and antigen combination potentiate the immune response towards conserved epitopes of the malaria vaccine candidate MSP2. Vaccine 39:12, pages 1746-1757.
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Rafiou Adamou, Célia Dechavanne, Ibrahim Sadissou, Tania d’Almeida, Aziz Bouraima, Paulin Sonon, Roukiyath Amoussa, Gilles Cottrell, Agnès Le Port, Michael Theisen, Edmond J. Remarque, Shirley Longacre, Kabirou Moutairou, Achille Massougbodji, Adrian J. F. Luty, Gregory Nuel, Florence Migot-Nabias, Ambaliou Sanni, André Garcia, Jacqueline Milet & David Courtin. (2019) Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort. Malaria Journal 18:1.
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Desye Misganaw, Ephrem Engidawork & Teshome Nedi. (2019) Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice. BMC Complementary and Alternative Medicine 19:1.
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Eric Houngla Adjakossa, Norbert Mahouton Hounkonnou & Grégory Nuel. (2019) Computationally Stable Estimation Procedure for the Multivariate Linear Mixed-Effect Model and Application to Malaria Public Health Problem. The International Journal of Biostatistics 15:2.
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Chenghui Lu, Xue Zheng, Wei Zhang, Hongxin Zhao, Christopher A. MacRaild, Raymond S. Norton, Yonglong Zhuang, Junfeng Wang & Xuecheng Zhang. (2019) Interaction of merozoite surface protein 2 with lipid membranes. FEBS Letters 593:3, pages 288-295.
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Bankala Krishnarjuna, Toshihiko Sugiki, Rodrigo A. V. Morales, Jeffrey Seow, Toshimichi Fujiwara, Karyn L. Wilde, Raymond S. Norton & Christopher A. MacRaild. (2018) Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope. Communications Biology 1:1.
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Christopher A. MacRaild, Jeffrey Seow, Sreedam C. Das & Raymond S. Norton. (2018) Disordered epitopes as peptide vaccines. Peptide Science 110:3.
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W. Ripley Ballou & Johan Vekemans. 2018. Plotkin's Vaccines. Plotkin's Vaccines 561 566.e3 .
Sreedam C. Das, Rodrigo A.V. Morales, Jeffrey Seow, Bankala Krishnarjuna, Ravindu Dissanayake, Robin F. Anders, Christopher A. MacRaild & Raymond S. Norton. (2017) Lipid interactions modulate the structural and antigenic properties of the C‐terminal domain of the malaria antigen merozoite surface protein 2. The FEBS Journal 284:16, pages 2649-2662.
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Jeffrey Seow, Rodrigo A.V. Morales, Christopher A. MacRaild, Bankala Krishnarjuna, Sheena McGowan, Tamir Dingjan, Garima Jaipuria, Romain Rouet, Karyn L. Wilde, Hanudatta S. Atreya, Jack S. Richards, Robin F. Anders, Daniel Christ, Nyssa Drinkwater & Raymond S. Norton. (2017) Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2. Journal of Molecular Biology 429:6, pages 836-846.
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Luiz Miguel Pereira, Luciana Baroni, Marcos Bezerra & Ana Patr?cia Yatsuda. (2017) A hybrid plasmid pGEM-pET28 applied for heterologous expression of Neospora caninum actin. Matters.
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Shane M. Devine, Christopher A. MacRaild, Raymond S. Norton & Peter J. Scammells. (2017) Antimalarial drug discovery targeting apical membrane antigen 1. MedChemComm 8:1, pages 13-20.
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Célia Dechavanne, Ibrahim Sadissou, Aziz Bouraima, Claude Ahouangninou, Roukiyath Amoussa, Jacqueline Milet, Kabirou Moutairou, Achille Massougbodji, Michael Theisen, Edmond J. Remarque, David Courtin, Gregory Nuel, Florence Migot-Nabias & André Garcia. (2016) Acquisition of natural humoral immunity to P. falciparum in early life in Benin: impact of clinical, environmental and host factors. Scientific Reports 6:1.
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Raymond Norton, Eleanor Leung, Indu Chandrashekaran & Christopher MacRaild. (2016) Applications of 19F-NMR in Fragment-Based Drug Discovery. Molecules 21:7, pages 860.
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Rafiou Adamou, Francine Ch?nou, Ibrahim Sadissou, Paulin Sonon, C?lia Dechavanne, Abdelkader Djilali-Sa?ah, Gilles Cottrell, Agn?s Le Port, Achille Massougbodji, Edmond J. Remarque, Adrian J.F. Luty, Ambaliou Sanni, Andr? Garcia, Florence Migot-Nabias, Jacqueline Milet & David Courtin. (2016) Plasmodium falciparum infection and age influence parasite growth inhibition mediated by IgG in Beninese infants. Acta Tropica 159, pages 111-119.
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Rodrigo A. V. Morales, Christopher A. MacRaild, Jeffrey Seow, Bankala Krishnarjuna, Nyssa Drinkwater, Romain Rouet, Robin F. Anders, Daniel Christ, Sheena McGowan & Raymond S. Norton. (2015) Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate. Scientific Reports 5:1.
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Christopher A. MacRaild, Milan Zachrdla, Dean Andrew, Bankala Krishnarjuna, Jiří Nováček, Lukáš Žídek, Vladimír Sklenář, Jack S. Richards, James G. Beeson, Robin F. Anders & Raymond S. Norton. (2015) Conformational Dynamics and Antigenicity in the Disordered Malaria Antigen Merozoite Surface Protein 2. PLOS ONE 10:3, pages e0119899.
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Ulrich Terheggen, Damien R Drew, Anthony N Hodder, Nadia J Cross, Cleopatra K Mugyenyi, Alyssa E Barry, Robin F Anders, Sheetij Dutta, Faith HA Osier, Salenna R Elliott, Nicolas Senn, Danielle I Stanisic, Kevin Marsh, Peter M Siba, Ivo Mueller, Jack S Richards & James G Beeson. (2014) Limited antigenic diversity of Plasmodium falciparumapical membrane antigen 1 supports the development of effective multi-allele vaccines. BMC Medicine 12:1.
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San Sui Lim, Wei Yang, Bankala Krishnarjuna, Komagal Kannan Sivaraman, Indu R. Chandrashekaran, Itamar Kass, Christopher A. MacRaild, Shane M. Devine, Cael O. Debono, Robin F. Anders, Martin J. Scanlon, Peter J. Scammells, Raymond S. Norton & Sheena McGowan. (2014) Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO . Biochemistry 53:46, pages 7310-7320.
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Karen S. Harris, Christopher G. Adda, Madhavi Khore, Damien R. Drew, Antonina Valentini-Gatt, Freya J. I. Fowkes, James G. Beeson, Sheetij Dutta, Robin F. Anders & Michael Foley. (2014) Use of Immunodampening To Overcome Diversity in the Malarial Vaccine Candidate Apical Membrane Antigen 1. Infection and Immunity 82:11, pages 4707-4717.
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G. Chittibabu, Charles Ma, Hans J. Netter, Santosh B. Noronha & Ross L. Coppel. (2013) Production, characterization, and immunogenicity of a secreted form of Plasmodium falciparum merozoite surface protein 4 produced in Bacillus subtilis. Applied Microbiology and Biotechnology 98:8, pages 3669-3678.
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Xuecheng Zhang, Yuanqiu Dong, Jigang Yu & Xiaoming Tu. (2013) Effects of environmental factors on MSP21–25 aggregation indicate the roles of hydrophobic and electrostatic interactions in the aggregation process. European Biophysics Journal 43:1, pages 1-9.
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Kevin K. A. Tetteh, Faith H. A. Osier, Ali Salanti, Gathoni Kamuyu, Laura Drought, Marilyne Failly, Christophe Martin, Kevin Marsh & David J. Conway. (2013) Analysis of Antibodies to Newly Described Plasmodium falciparum Merozoite Antigens Supports MSPDBL2 as a Predicted Target of Naturally Acquired Immunity. Infection and Immunity 81:10, pages 3835-3842.
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José Luis Corchero, Brigitte Gasser, David Resina, Wesley Smith, Ermenegilda Parrilli, Felícitas Vázquez, Ibane Abasolo, Maria Giuliani, Jussi Jäntti, Pau Ferrer, Markku Saloheimo, Diethard Mattanovich, Simó SchwartzJr.Jr., Maria Luisa Tutino & Antonio Villaverde. (2013) Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics. Biotechnology Advances 31:2, pages 140-153.
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Brigitte Gasser, Roland Prielhofer, Hans Marx, Michael Maurer, Justyna Nocon, Matthias Steiger, Verena Puxbaum, Michael Sauer & Diethard Mattanovich. (2013) Pichia pastoris : protein production host and model organism for biomedical research . Future Microbiology 8:2, pages 191-208.
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Sejal Gohil, Susann Herrmann, Svenja G?nther & Brian M. Cooke. (2013) Bovine babesiosis in the 21st century: Advances in biology and functional genomics. International Journal for Parasitology 43:2, pages 125-132.
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W. Ripley Ballou & Joe Cohen. 2013. Vaccines. Vaccines 1133 1137 .
Damien R. Drew, Anthony N. Hodder, Danny W. Wilson, Michael Foley, Ivo Mueller, Peter M. Siba, Arlene E. Dent, Alan F. Cowman & James G. Beeson. (2012) Defining the Antigenic Diversity of Plasmodium falciparum Apical Membrane Antigen 1 and the Requirements for a Multi-Allele Vaccine against Malaria. PLoS ONE 7:12, pages e51023.
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Christopher A. MacRaild, Marie ?. Pedersen, Robin F. Anders & Raymond S. Norton. (2012) Lipid interactions of the malaria antigen merozoite surface protein 2. Biochimica et Biophysica Acta (BBA) - Biomembranes 1818:11, pages 2572-2578.
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Alan F. Cowman, Drew Berry & Jake Baum. (2012) The cellular and molecular basis for malaria parasite invasion of the human red blood cell. Journal of Cell Biology 198:6, pages 961-971.
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Takeshi Ono, Yoko Yamaguchi, Takemi Oguma, Eiji Takayama, Yasuhiro Takashima, Takushi Tadakuma & Yasushi Miyahira. (2012) Actively induced antigen-specific CD8+ T cells by epitope-bearing parasite pre-infection but not prime/boost virus vector vaccination could ameliorate the course of Plasmodium yoelii blood-stage infection. Vaccine 30:44, pages 6270-6278.
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Yanhui Zhang, Yanwei Qi, Jian Li, Shengfa Liu, Lingxian Hong, Tianlong Lin, Carole Long & Xin-zhuan Su. (2011) A new malaria antigen produces partial protection against Plasmodium yoelii challenge. Parasitology Research 110:4, pages 1337-1345.
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Xuecheng Zhang, Christopher G. Adda, Andrew Low, Jiahai Zhang, Wen Zhang, Hongbin Sun, Xiaoming Tu, Robin F. Anders & Raymond S. Norton. (2012) Role of the Helical Structure of the N-Terminal Region of Plasmodium falciparum Merozoite Surface Protein 2 in Fibril Formation and Membrane Interaction . Biochemistry 51:7, pages 1380-1387.
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Anthony Bouillon, Olivier Gorgette, Odile Mercereau-Puijalon & Jean-Christophe Barale. 2013. Malaria. Malaria 523 534 .
John C Reeder, Johanna Wapling, Ivo Mueller, Peter M Siba & Alyssa E Barry. (2011) Population genetic analysis of the Plasmodium falciparum 6-cys protein Pf38 in Papua New Guinea reveals domain-specific balancing selection. Malaria Journal 10:1.
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Adrian V. S. Hill. (2011) Vaccines against malaria. Philosophical Transactions of the Royal Society B: Biological Sciences 366:1579, pages 2806-2814.
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James S. McCarthy, Joanne Marjason, Suzanne Elliott, Paul Fahey, Gilles Bang, Elissa Malkin, Eveline Tierney, Hayley Aked-Hurditch, Christopher Adda, Nadia Cross, Jack S. Richards, Freya J. I. Fowkes, Michelle J. Boyle, Carole Long, Pierre Druilhe, James G. Beeson & Robin F. Anders. (2011) A Phase 1 Trial of MSP2-C1, a Blood-Stage Malaria Vaccine Containing 2 Isoforms of MSP2 Formulated with Montanide® ISA 720. PLoS ONE 6:9, pages e24413.
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Robin F. Anders. (2011) The case for a subunit vaccine against malaria. Trends in Parasitology 27:8, pages 330-334.
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Patrick Georges Cech, Thomas Aebi, Mwanajaa Shomari Abdallah, Maxmillian Mpina, Ester Barnabas Machunda, Nicole Westerfeld, Sabine Alexandra Stoffel, Rinaldo Zurbriggen, Gerd Pluschke, Marcel Tanner, Claudia Daubenberger, Blaise Genton & Salim Abdulla. (2011) Virosome-Formulated Plasmodium falciparum AMA-1 & CSP Derived Peptides as Malaria Vaccine: Randomized Phase 1b Trial in Semi-Immune Adults & Children. PLoS ONE 6:7, pages e22273.
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Erinna F. Lee, Shenggen Yao, Jennifer K. Sabo, W. Douglas Fairlie, Rachel A. Stevenson, Karen S. Harris, Robin F. Anders, Michael Foley & Raymond S. Norton. (2011) Peptide inhibitors of the malaria surface protein, apical membrane antigen 1: Identification of key binding residues. Biopolymers 95:5, pages 354-364.
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Xiaodong Yang, Christopher G. Adda, Christopher A. MacRaild, Andrew Low, Xuecheng Zhang, Weiguang Zeng, David C. Jackson, Robin F. Anders & Raymond S. Norton. (2010) Identification of key residues involved in fibril formation by the conserved N-terminal region of Plasmodium falciparum merozoite surface protein 2 (MSP2). Biochimie 92:10, pages 1287-1295.
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Andrew M. Redmond & Denise L. Doolan. (2010) The Australasian Contribution to Malaria Vaccine Development. Parasite Immunology, pages no-no.
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