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Special Focus Review

Advances and hurdles on the way toward a leprosy vaccine

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Pages 1172-1183 | Received 06 Jun 2011, Accepted 25 Jul 2011, Published online: 01 Nov 2011

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Mariko Sugawara-Mikami, Kazunari Tanigawa, Akira Kawashima, Mitsuo Kiriya, Yasuhiro Nakamura, Yoko Fujiwara & Koichi Suzuki. (2022) Pathogenicity and virulence of Mycobacterium leprae. Virulence 13:1, pages 1985-2011.
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Garrett L. Vick, Erica A. Tillman & Katherine H. Fiala. (2015) Leprosy in a Texan. Baylor University Medical Center Proceedings 28:2, pages 231-232.
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Sophie M Worobec. (2012) Current approaches and future directions in the treatment of leprosy. Research and Reports in Tropical Medicine 3, pages 79-91.
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Kou-Huang Chen, Cheng-Yao Lin, Shih-Bin Su & Kow-Tong Chen. (2022) Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management. Journal of Tropical Medicine 2022, pages 1-13.
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Sebastião Marcio Da Silva Vieira, Luis Felipe Silva de Lima, Pedro Alves Soares Vaz de Castro Alves Soares Vaz de Castro & Juliana Maria Trindade Bezerra. (2022) Aspectos sobre a patogênese, a clínica, o diagnóstico e o tratamento da hanseníase: uma revisão narrativa. Journal of Education Science and Health 2:2, pages 1-11.
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Peter J. Hotez. 2021. Forgotten People, Forgotten Diseases. Forgotten People, Forgotten Diseases 95 110 .
Lasida Ali. (2021) Leprosy vaccines – A voyage unfinished. Journal of Skin and Sexually Transmitted Diseases 3, pages 40-45.
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Malaisamy Muniyandi, Malkeet Singh, Manjula Singh, Kavitha Rajshekhar & Kiran Katoch. (2021) Cost-effectiveness of incorporating Mycobacterium indicus pranii vaccine to multidrug therapy in newly diagnosed leprosy cases for better treatment outcomes & immunoprophylaxis in contacts as leprosy control measures for National Leprosy Eradication Programme in India. Indian Journal of Medical Research 154:1, pages 121.
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Hadida Yasmin, Praveen Mathews Varghese, Sanjib Bhakta & Uday Kishore. 2021. Microbial Pathogenesis. Microbial Pathogenesis 155 177 .
S. Ballivet de Régloix, O. Maurin, J.-B. Caruhel, M. Tondu, P. Clément & Y. Pons. (2020) Manifestaciones otorrinolaringológicas de enfermedades infecciosas específicas. EMC - Otorrinolaringología 49:2, pages 1-16.
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Rafaela Resende Gomes, Douglas Eulálio Antunes, Diogo Fernandes dos Santos, Elaine Fávaro Pípi Sabino, Dulcinéia Bernardes Oliveira & Isabela Maria Bernardes Goulart. (2019) BCG vaccine and leprosy household contacts: Protective effect and probability to becoming sick during follow-up. Vaccine 37:43, pages 6510-6517.
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Márcio Bezerra Santos, Allan Dantas dos Santos, Aline Silva Barreto, Mariana do Rosário Souza, Marco Aurélio de Oliveira Goes, José Antônio Barreto Alves, Ikaro Daniel Carvalho Barreto, José-Rodrigo S Silva, Daniela Teles de Oliveira, Karina C G Machado de Araújo, Malcolm S Duthie & Amélia Ribeiro de Jesus. (2019) Clinical and epidemiological indicators and spatial analysis of leprosy cases in patients under 15 years old in an endemic area of Northeast Brazil: an ecological and time series study. BMJ Open 9:7, pages e023420.
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Márcio Bezerra-Santos, Marise do Vale-Simon, Aline Silva Barreto, Rodrigo Anselmo Cazzaniga, Daniela Teles de Oliveira, Mônica Rueda Barrios, Alex Ricardo Ferreira, Nanci C. Santos-Bio, Steven G. Reed, Roque Pacheco de Almeida, Cristiane Bani Corrêa, Malcolm S. Duthie & Amélia Ribeiro de Jesus. (2018) Mycobacterium leprae Recombinant Antigen Induces High Expression of Multifunction T Lymphocytes and Is Promising as a Specific Vaccine for Leprosy. Frontiers in Immunology 9.
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N. Schöffel, M. Braun, G. Volante, M. H. K. Bendels & D. A. Groneberg. (2017) LepraLeprosy. Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie 68:5, pages 270-273.
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Mariateresa Coppola, Susan J. F. van den Eeden, Naoko Robbins, Louis Wilson, Kees L. M. C. Franken, Linda B. Adams, Tom P. Gillis, Tom H. M. Ottenhoff & Annemieke Geluk. (2018) Vaccines for Leprosy and Tuberculosis: Opportunities for Shared Research, Development, and Application. Frontiers in Immunology 9.
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M. B. Santos, D. T. de Oliveira, R. A. Cazzaniga, C. S. Varjão, P. L. dos Santos, M. L. B. Santos, C. B. Correia, D. R. Faria, M. do V. Simon, J. S. Silva, W. O. Dutra, S. G. Reed, M. S. Duthie, R. P. de Almeida & A. R. de Jesus. (2017) Distinct Roles of Th17 and Th1 Cells in Inflammatory Responses Associated with the Presentation of Paucibacillary Leprosy and Leprosy Reactions. Scandinavian Journal of Immunology 86:1, pages 40-49.
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Irwin W. Sherman. 2017. The Power of Plagues. The Power of Plagues 466 484 .
Jan Hendrik Richardus, David Pahan, Roch Christian Johnson & W Cairns S Smith. 2016. International textbook of leprosy. International textbook of leprosy.
Luigi Bernini, Carlo Umberto Manzini & Clodoveo Ferri. 2015. Vaccines and Autoimmunity. Vaccines and Autoimmunity 197 206 .
Renate A. Richardus, C. Ruth Butlin, Khorshed Alam, Kallyan Kundu, Annemieke Geluk & Jan Hendrik Richardus. (2015) Clinical manifestations of leprosy after BCG vaccination: An observational study in Bangladesh. Vaccine 33:13, pages 1562-1567.
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M. Raynal, T. Le Guyadec, P. Le Page, Y. Pons, J. Grinholtz, Q. Lisan, S. De Regloix & M. Kossowski. (2015) Manifestazioni ORL delle malattie infettive specifiche. EMC - Otorinolaringoiatria 14:1, pages 1-14.
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M. Raynal, T. Le Guyadec, P. Le Page, Y. Pons, J. Grinholtz, Q. Lisan, S. De Regloix & M. Kossowski. (2015) Manifestaciones ORL de enfermedades infecciosas específicas. EMC - Otorrinolaringología 44:1, pages 1-15.
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Jan Hendrik Richardus & Linda Oskam. (2015) Protecting people against leprosy: Chemoprophylaxis and immunoprophylaxis. Clinics in Dermatology 33:1, pages 19-25.
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Tim K. Mackey, Bryan A. Liang, Raphael Cuomo, Ryan Hafen, Kimberly C. Brouwer & Daniel E. Lee. (2014) Emerging and Reemerging Neglected Tropical Diseases: a Review of Key Characteristics, Risk Factors, and the Policy and Innovation Environment. Clinical Microbiology Reviews 27:4, pages 949-979.
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Malcolm S. Duthie, Rhea N. Coler, John D. Laurance, Lucas H. Sampaio, Regiane M. Oliveira, Ana Lucia M. Sousa, Mariane M. A. Stefani, Yumi Maeda, Masanori Matsuoka, Masahiko Makino & Steven G. Reed. (2014) Protection against Mycobacterium leprae Infection by the ID83/GLA-SE and ID93/GLA-SE Vaccines Developed for Tuberculosis. Infection and Immunity 82:9, pages 3979-3985.
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Thomas P. Gillis, Michael V. Tullius & Marcus A. Horwitz. (2014) rBCG30-Induced Immunity and Cross-Protection against Mycobacterium leprae Challenge Are Enhanced by Boosting with the Mycobacterium tuberculosis 30-Kilodalton Antigen 85B. Infection and Immunity 82:9, pages 3900-3909.
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Cairns S Smith, Shaik Kahder Noordeen, Jan Hendrik Richardus, Hubert Sansarricq, Stewart T Cole, Rosa Castãlia Soares, Lorenzo Savioli, Ann Aertsh & Sumana Baruaf. (2014) A strategy to halt leprosy transmission. The Lancet Infectious Diseases 14:2, pages 96-98.
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Malcolm S. Duthie, Lucas H. Sampaio, Regiane M. Oliveira, Vanitha S. Raman, Joanne O’Donnell, H. Remy Bailor, Greg C. Ireton, Ana Lucia M. Sousa, Mariane M.A. Stefani & Steven G. Reed. (2013) Development and pre-clinical assessment of a 73kD chimeric fusion protein as a defined sub-unit vaccine for leprosy. Vaccine 31:5, pages 813-819.
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Malcolm S Duthie, Paul Saunderson & Steven G Reed. (2012) The potential for vaccination in leprosy elimination: new tools for targeted interventions. Memórias do Instituto Oswaldo Cruz 107:suppl 1, pages 190-196.
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Rahul SharmaRamanuj Lahiri, David M. Scollard, Maria PenaDiana L. Williams, Linda B. Adams, John Figarola & Richard W. Truman. (2012) The armadillo: a model for neuropathy of leprosy and potentially other neurodegenerative diseases. Disease Models & Mechanisms.
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