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Islets Volume 4, 2012 - Issue 3

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Research Paper

Pancreatic magnetic resonance imaging after manganese injection distinguishes type 2 diabetic and normoglycemic patients

Diomidis Botsikas Department of Radiology; Geneva University Hospital; Geneva, Switzerland

Sylvain Terraz Department of Radiology; Geneva University Hospital; Geneva, Switzerland

Laurent Vinet Department of Cell Physiology and Metabolism; Geneva University; Geneva, Switzerland

Smaragda Lamprianou Department of Cell Physiology and Metabolism; Geneva University; Geneva, Switzerland

Christoph D. Becker Department of Radiology; Geneva University Hospital; Geneva, Switzerland

Domenico Bosco Department of Surgery; Geneva University Hospital; Geneva, Switzerland

Paolo Meda Department of Cell Physiology and Metabolism; Geneva University; Geneva, Switzerland

Xavier Montet Department of Radiology; Geneva University Hospital; Geneva, SwitzerlandCorrespondence[email protected]

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Pages 243-248 | Published online: 01 May 2012

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https://doi.org/10.4161/isl.20857

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Shruti S. Joshi, Trisha Singh, Lucy E. Kershaw, Fraser W. Gibb, Marc R. Dweck, Michelle Williams, Iskandar Idris, Scott Semple, Shareen Forbes, David E. Newby & Rebecca M. Reynolds. (2023) Non‐invasive imaging of functional pancreatic islet beta‐cell mass in people with type 1 diabetes mellitus. Diabetic Medicine.
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Trisha Singh, Shruti Joshi, Lucy E Kershaw, Marc R Dweck, Scott I Semple & David E Newby. (2022) Manganese‐Enhanced Magnetic Resonance Imaging of the Heart . Journal of Magnetic Resonance Imaging 57:4, pages 1011-1028.
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Per Jynge, Arne M. Skjold, Ursula Falkmer, Rolf G. G. Andersson, John G. Seland, Morten Bruvold, Viggo Blomlie, Willy Eidsaunet & Jan O. G. Karlsson. (2020) MnDPDP: Contrast Agent for Imaging and Protection of Viable Tissue. Contrast Media & Molecular Imaging 2020, pages 1-17.
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Goh Zheng Cong, Krishna Kanta Ghosh, Sachin Mishra, Miklós Gulyás, Tibor Kovács, Domokos Máthé, Parasuraman Padmanabhan & Balázs Gulyás. (2020) Targeted pancreatic beta cell imaging for early diagnosis. European Journal of Cell Biology 99:7, pages 151110.
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Nam-Young Kang, Jung Yeol Lee, Sang Hee Lee, In Ho Song, Yong Hwa Hwang, Min Jun Kim, Wut Hmone Phue, Bikram Keshari Agrawalla, Si Yan Diana Wan, Janise Lalic, Sung-Jin Park, Jong-Jin Kim, Haw-Young Kwon, So Hee Im, Myung Ae Bae, Jin Hee Ahn, Chang Siang Lim, Adrian Kee Keong Teo, Sunyou Park, Sang Eun Kim, Byung Chul Lee, Dong Yun Lee & Young-Tae Chang. (2020) Multimodal Imaging Probe Development for Pancreatic β Cells: From Fluorescence to PET. Journal of the American Chemical Society 142:7, pages 3430-3439.
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Lucy E Kershaw, David ML Lilburn, Maurits A. Jansen, Andrew R Bond, Salamah M Alwahsh, Pilar Jimenez-Royo, Antonella Napolitano, Philip Murphy, Alexandra Roberts, Rob Janiczek, Shareen Forbes & Scott IK Semple. (2019) Manganese-enhanced MRI: Comparison of agents in the rat pancreas. Journal of Magnetic Resonance Open 1, pages 100002.
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Weijun Wei, Emily B. Ehlerding, Xiaoli Lan, Quan-Yong Luo & Weibo Cai. (2019) Molecular imaging of β-cells: diabetes and beyond. Advanced Drug Delivery Reviews 139, pages 16-31.
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Nadine Mallak, Thomas A. Hope & Alexander R. Guimaraes. (2018) PET/MR Imaging of the Pancreas. Magnetic Resonance Imaging Clinics of North America 26:3, pages 345-362.
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Zeeshan Ali, P. Charukeshi Chandrasekera & John J. Pippin. (2018) Animal Research for Type 2 Diabetes Mellitus, Its Limited Translation for Clinical Benefit, and the Way Forward. Alternatives to Laboratory Animals 46:1, pages 13-22.
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Chunguang Chen, Christian M. Cohrs, Julia Stertmann, Robert Bozsak & Stephan Speier. (2017) Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis. Molecular Metabolism 6:9, pages 943-957.
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Andreas Jodal, Roger Schibli & Martin Béhé. (2016) Targets and probes for non-invasive imaging of β-cells. European Journal of Nuclear Medicine and Molecular Imaging 44:4, pages 712-727.
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Luc Driencourt, Carola Jacqueline Romero, Mario Lepore, Florent Eggenschwiler, Olivier Reynaud & Nathalie Just. (2016) T1 mapping of the mouse brain following fractionated manganese administration using MP2RAGE. Brain Structure and Function 222:1, pages 201-214.
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Nikhil Rammohan, Keith W. MacRenaris, Laura K. Moore, Giacomo Parigi, Daniel J. Mastarone, Lisa M. Manus, Laura M. Lilley, Adam T. Preslar, Emily A. Waters, Abigail Filicko, Claudio Luchinat, Dean Ho & Thomas J. Meade. (2016) Nanodiamond–Gadolinium(III) Aggregates for Tracking Cancer Growth In Vivo at High Field. Nano Letters 16:12, pages 7551-7564.
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Robert J. Holbrook, Nikhil Rammohan, Matthew W. Rotz, Keith W. MacRenaris, Adam T. Preslar & Thomas J. Meade. (2016) Gd(III)-Dithiolane Gold Nanoparticles for T 1 -Weighted Magnetic Resonance Imaging of the Pancreas . Nano Letters 16:5, pages 3202-3209.
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D. Laurent, L. Vinet, S. Lamprianou, M. Daval, G. Filhoulaud, A. Ktorza, H. Wang, S. Sewing, H.-P. Juretschke, H. Glombik, P. Meda, R. Boisgard, D. L. Nguyen, G. J. Stasiuk, N. J. Long, X. Montet, P. Hecht, W. Kramer, G. A. Rutter & J. Hecksher-Sørensen. (2016) Pancreatic β-cell imaging in humans: fiction or option?. Diabetes, Obesity and Metabolism 18:1, pages 6-15.
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Oliver Plettenburg & Matthias Löhn. 2015. Small Molecule Medicinal Chemistry. Small Molecule Medicinal Chemistry 465 501 .

Anke Meyer, Katharina Stolz, Wolfgang Dreher, Jennifer Bergemann, Vani Holebasavanahalli Thimmashetty, Navina Lueschen, Zahra Azizi, Vrushali Khobragade, Kathrin Maedler & Ekkehard Kuestermann. (2015) Manganese-Mediated MRI Signals Correlate With Functional β-Cell Mass During Diabetes Progression. Diabetes 64:6, pages 2138-2147.
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Laurent Vinet, Smaragda Lamprianou, Andrej Babič, Norbert Lange, Fabrizio Thorel, Pedro Luis Herrera, Xavier Montet & Paolo Meda. (2014) Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice. Diabetologia 58:2, pages 304-312.
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Xavier Montet, Smaragda Lamprianou, Laurent Vinet, Paolo Meda & Alfredo Fort. 2015. Islets of Langerhans. Islets of Langerhans 59 81 .

Willy J Malaisse. (2014) L'imagerie non-invasive des cellules productrices d'insuline. Research fr1.
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Xavier Montet, Smaragda Lamprianou, Laurent Vinet, Paolo Meda & Alfredo Fort. 2013. Islets of Langerhans, 2. ed.. Islets of Langerhans, 2. ed. 1 21 .

Ping Wang & Anna Moore. (2013) Translational Molecular Imaging of Diabetes. Current Radiology Reports 1:3, pages 205-215.
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Pancreatic magnetic resonance imaging after manganese injection distinguishes type 2 diabetic and normoglycemic patients

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Pancreatic magnetic resonance imaging after manganese injection distinguishes type 2 diabetic and normoglycemic patients

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