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Islets Volume 4, 2012 - Issue 6
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Research Paper

Gene transfer of active Akt1 by an infectivity-enhanced adenovirus impacts β-cell survival and proliferation differentially in vitro and in vivo

Robert N. Bone Department of Pathology; University of Alabama at Birmingham; Birmingham, AL USA
,
Mert Icyuz Department of Medicine; University of Alabama at Birmingham; Birmingham, AL USA
,
Yanqing Zhang Department of Medicine; Section of Endocrinology; Tulane University; New Orleans, LA USA
,
Yuan Zhang Department of Medicine; University of Alabama at Birmingham; Birmingham, AL USA
,
Wanxing Cui Department of Surgery; University of Alabama at Birmingham; Birmingham, AL USA
,
Hongjun Wang Department of Surgery; Medical University of South Carolina; Charleston, SC USA
,
Ji-Bin Peng Department of Medicine; University of Alabama at Birmingham; Birmingham, AL USA
,
Qiana L. Matthews Department of Medicine; University of Alabama at Birmingham; Birmingham, AL USA
,
Gene P. Siegal Department of Pathology; University of Alabama at Birmingham; Birmingham, AL USA
&
Hongju Wu Department of Medicine; Section of Endocrinology; Tulane University; New Orleans, LA USACorrespondence[email protected]
 show all
Pages 366-378 | Published online: 01 Nov 2012

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Yoshiki Nakashima, Chika Miyagi-Shiohira, Naoya Kobayashi, Issei Saitoh, Masami Watanabe & Hirofumi Noguchi. (2018) Adhesion characteristics of porcine pancreatic islets and exocrine tissue to coating materials. Islets 10:3.
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Shengli Dong & Hongju Wu. (2018) Regenerating β cells of the pancreas – potential developments in diabetes treatment. Expert Opinion on Biological Therapy 18:2, pages 175-185.
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Yuliya Dvoretskaya, Victor Glanz, Mariya Gryaznova, Mikhail Syromyatnikov & Vasily Popov. (2021) Mitochondrial Antioxidant SkQ1 Has a Beneficial Effect in Experimental Diabetes as Based on the Analysis of Expression of microRNAs and mRNAs for the Oxidative Metabolism Regulators. Antioxidants 10:11, pages 1749.
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Saima Kh & Khawaja Husnain Haider. 2021. Stem Cells. Stem Cells 185 202 .
Keshab R. Parajuli, Yanqing Zhang, Alexander M. Cao, Hongjun Wang, Vivian A. Fonseca & Hongju Wu. (2020) Pax4 Gene Delivery Improves Islet Transplantation Efficacy by Promoting β Cell Survival and α-to-β Cell Transdifferentiation. Cell Transplantation 29, pages 096368972095865.
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Yanqing Zhang, Meifen Wu, Wynn Htun, Emily W. Dong, Franck Mauvais-Jarvis, Vivian A. Fonseca & Hongju Wu. (2017) Differential Effects of Linagliptin on the Function of Human Islets Isolated from Non-diabetic and Diabetic Donors. Scientific Reports 7:1.
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Virginia Haurigot, Veronica Jimenez & Fatima Bosch. 2017. Textbook of Diabetes. Textbook of Diabetes 1029 1037 .
Yanqing Zhang, Genevieve E Fava, Hongjun Wang, Franck Mauvais-Jarvis, Vivian A Fonseca & Hongju Wu. (2016) PAX4 Gene Transfer Induces α-to-β Cell Phenotypic Conversion and Confers Therapeutic Benefits for Diabetes Treatment. Molecular Therapy 24:2, pages 251-260.
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Maren G. Dietrich, Richard A. Zuellig, Giatgen A. Spinas, Roger Lehmann, Oliver Tschopp & Markus Niessen. (2015) Specific and redundant roles of PKBα/AKT1 and PKBβ/AKT2 in human pancreatic islets. Experimental Cell Research 338:1, pages 82-88.
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Hiroyuki Hanayama, Kazuo Ohashi, Rie Utoh, Hirofumi Shimizu, Kazuya Ise, Fuminori Sakurai, Hiroyuki Mizuguchi, Hiroyuki Tsuchiya, Teruo Okano & Mitsukazu Gotoh. (2015) Efficient Gene Transduction of Dispersed Islet Cells in Culture Using Fiber-Modified Adenoviral Vectors. Cell Medicine 8:1-2, pages 31-38.
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Thomas J. O'Malley, Genevieve E. Fava, Yanqing Zhang, Vivian A. Fonseca & Hongju Wu. (2014) Progressive change of intra-islet GLP-1 production during diabetes development. Diabetes/Metabolism Research and Reviews 30:8, pages 661-668.
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Neha Shrestha, Francisca Araújo, Bruno Sarmento, Jouni Hirvonen & Hélder A Santos. (2014) Gene-based therapy for Type 1 diabetes mellitus: viral and nonviral vectors. Diabetes Management 4:4, pages 367-380.
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Jack M. HeathYong SunKaiyu YuanWayne E. BradleySilvio LitovskyLouis J. Dell’ItaliaJohn C. ChathamHui WuYabing Chen. (2014) Activation of AKT by O-Linked N-Acetylglucosamine Induces Vascular Calcification in Diabetes Mellitus. Circulation Research 114:7, pages 1094-1102.
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Kate Banks, Tairan Qin, Tao Liang, An Jing Wang & Herbert Y. Gaisano. (2014) Biliopancreatic Route for Effective Viral Transduction of Pancreatic Islets. Pancreas 43:2, pages 240-244.
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Vecihi Batuman. 2014. Diabetes and Kidney Disease. Diabetes and Kidney Disease 241 250 .
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