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Review

Antigen-based vs. systemic immunomodulation in type 1 diabetes

The pros and cons

Sofie Robert Clinical and Experimental Endocrinology; Katholieke Universiteit Leuven; Campus Gasthuisberg; Leuven, Belgium
,
Hannelie Korf Clinical and Experimental Endocrinology; Katholieke Universiteit Leuven; Campus Gasthuisberg; Leuven, Belgium
,
Conny Gysemans Clinical and Experimental Endocrinology; Katholieke Universiteit Leuven; Campus Gasthuisberg; Leuven, BelgiumCorrespondence[email protected]
&
Chantal Mathieu Clinical and Experimental Endocrinology; Katholieke Universiteit Leuven; Campus Gasthuisberg; Leuven, Belgium
Pages 53-66 | Received 08 Jan 2013, Accepted 20 Apr 2013, Published online: 01 Mar 2013

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Nadir Askenasy. (2015) Less Is More: The Detrimental Consequences of Immunosuppressive Therapy in the Treatment of Type-1 Diabetes. International Reviews of Immunology 34:6, pages 523-537.
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Articles from other publishers (12)

Nick Giannoukakis. (2023) Tolerogenic dendritic cells in type 1 diabetes: no longer a concept. Frontiers in Immunology 14.
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Johnny Ludvigsson. (2022) Glutamic acid decarboxylase immunotherapy for type 1 diabetes. Current Opinion in Endocrinology, Diabetes & Obesity 29:4, pages 361-369.
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Anneli Björklund, Ingrid K. Hals, Valdemar Grill & Johnny Ludvigsson. (2022) Latent Autoimmune Diabetes in Adults: Background, Safety and Feasibility of an Ongoing Pilot Study With Intra-Lymphatic Injections of GAD-Alum and Oral Vitamin D. Frontiers in Endocrinology 13.
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Nina Hoeyrup, Thomas Spillmann & Linda Toresson. (2021) Cyclosporine Treatment in Cats with Presumed Chronic Pancreatitis—A Retrospective Study. Animals 11:10, pages 2993.
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Dante J. Marciani. (2021) Sole Anti-inflammatory Immunomodulators: Innovative Drugs to Prevent and Treat Autoimmune Diseases and Proteopathies. Current Chinese Science 1:2, pages 273-285.
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Rui-Feng Mao, Ying-Ying Chen, Ji Zhang, Xin Chang & Ye-Fu Wang. (2020) Type 1 diabetes mellitus and its oral tolerance therapy. World Journal of Diabetes 11:10, pages 400-415.
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Johnny Ludvigsson. (2020) Autoantigen Treatment in Type 1 Diabetes: Unsolved Questions on How to Select Autoantigen and Administration Route. International Journal of Molecular Sciences 21:5, pages 1598.
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Tatiana Takiishi, Dana Paulina Cook, Hannelie Korf, Guido Sebastiani, Francesca Mancarella, João Paulo Monteiro Carvalho Mori Cunha, Clive Wasserfall, Noelia Casares, Juan José Lasarte, Lothar Steidler, Pieter Rottiers, Francesco Dotta, Conny Gysemans & Chantal Mathieu. (2017) Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10–Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells . Diabetes 66:2, pages 448-459.
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Chrysoula Rizava, Eleni Bekiari, Aris Liakos, Maria Sarigianni, Maria Rika, Anna Bettina Haidich, Asimina Galli-Tsinopoulou & Apostolos Tsapas. (2016) Antigen-based immunotherapies do not prevent progression of recent-onset autoimmune diabetes: a systematic review and meta-analysis. Endocrine 54:3, pages 620-633.
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Felix Schreiner, Michaela Plamper, Gesche Dueker, Stefan Schoenberger, Laura Gámez-Díaz, Bodo Grimbacher, Alina C. Hilger, Bettina Gohlke, Heiko Reutter & Joachim Woelfle. (2016) Infancy-Onset T1DM, Short Stature, and Severe Immunodysregulation in Two Siblings With a Homozygous LRBA Mutation. The Journal of Clinical Endocrinology & Metabolism 101:3, pages 898-904.
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E. Laugesen, J. A. Østergaard & R. D. G. Leslie. (2015) Latent autoimmune diabetes of the adult: current knowledge and uncertainty. Diabetic Medicine 32:7, pages 843-852.
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Preeti Chhabra, David E.R. Sutherland & Kenneth L. Brayman. (2014) Overcoming barriers in clinical islet transplantation: Current limitations and future prospects. Current Problems in Surgery 51:2, pages 49-86.
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