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Tumor microenvironment in NSCLC suppresses NK cells function

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Pages 244-246 | Published online: 01 Mar 2012

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Laetitia Fend, Sylvie Rusakiewicz, Julien Adam, Bérangère Bastien, Anne Caignard, Meriem Messaoudene, Christina Iribarren, Isabelle Cremer, Aurélien Marabelle, Christophe Borg, Michaela Semeraro, Luc Barraud, Jean-Marc Limacher, Alexander Eggermont, Guido Kroemer & Laurence Zitvogel. (2017) Prognostic impact of the expression of NCR1 and NCR3 NK cell receptors and PD-L1 on advanced non-small cell lung cancer. OncoImmunology 6:1.
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Sébastien Viel, Emily Charrier, Antoine Marçais, Paul Rouzaire, Jacques Bienvenu, Lionel Karlin, Gilles Salles & Thierry Walzer. (2013) Monitoring NK cell activity in patients with hematological malignancies. OncoImmunology 2:9.
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Articles from other publishers (25)

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Alex N. Mueller, Samantha Morrisey, Hunter A. Miller, Xiaoling Hu, Rohit Kumar, Phuong T. Ngo, Jun Yan & Hermann B. Frieboes. (2022) Prediction of lung cancer immunotherapy response via machine learning analysis of immune cell lineage and surface markers. Cancer Biomarkers 34:4, pages 681-692.
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Seung-Jin Kim, Dipendra Khadka & Jae Ho Seo. (2022) Interplay between Solid Tumors and Tumor Microenvironment. Frontiers in Immunology 13.
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Sofia Raftopoulou, Paulina Valadez-Cosmes, Zala Nikita Mihalic, Rudolf Schicho & Julia Kargl. (2022) Tumor-Mediated Neutrophil Polarization and Therapeutic Implications. International Journal of Molecular Sciences 23:6, pages 3218.
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Hyeong-Woo Song, Han-Sol Lee, Seok-Jae Kim, Ho Yong Kim, You Hee Choi, Byungjeon Kang, Chang-Sei Kim, Jong-Oh Park & Eunpyo Choi. (2021) Sonazoid-Conjugated Natural Killer Cells for Tumor Therapy and Real-Time Visualization by Ultrasound Imaging. Pharmaceutics 13:10, pages 1689.
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Yongqin Zeng, Xiuzhi Lv & Juan Du. (2021) Natural killer cell‑based immunotherapy for lung cancer: Challenges and perspectives (Review). Oncology Reports 46:5.
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Leena Arora & Durba Pal. (2021) Remodeling of Stromal Cells and Immune Landscape in Microenvironment During Tumor Progression. Frontiers in Oncology 11.
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Nannan Yang, Kristin Lode, Rodrigo Berzaghi, Ashraful Islam, Inigo Martinez-Zubiaurre & Turid Hellevik. (2021) Irradiated Tumor Fibroblasts Avoid Immune Recognition and Retain Immunosuppressive Functions Over Natural Killer Cells. Frontiers in Immunology 11.
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Jingwen Zhang, Zhihao Zhang, Weiwei Song & Jumin Liu. (2020) EPHA5 mutation impairs natural killer cell-mediated cytotoxicity against non-small lung cancer cells and promotes cancer cell migration and invasion. Molecular and Cellular Probes 52, pages 101566.
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Xiaohu Zhou, Shanshan Liu, Jun Liu, Zixing Zhang, Xiaoming Mao & Hua Zhou. (2020) MicroRNA-130a enhances the killing ability of natural killer cells against non-small cell lung cancer cells by targeting signal transducers and activators of transcription 3. Biochemical and Biophysical Research Communications 523:2, pages 481-486.
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Lena Gaissmaier & Petros Christopoulos. (2020) Immune Modulation in Lung Cancer: Current Concepts and Future Strategies. Respiration 99:11, pages 903-929.
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Clara Di Vito, Joanna Mikulak, Elisa Zaghi, Silvia Pesce, Emanuela Marcenaro & Domenico Mavilio. (2019) NK cells to cure cancer. Seminars in Immunology 41, pages 101272.
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Liya Wu, Fuqiang Zhang, Zhenhong Wei, Xiuying Li, Hong Zhao, Huiying Lv, Rui Ge, He Ma, Hao Zhang, Bai Yang, Jing Li & Jinlan Jiang. (2018) Magnetic delivery of Fe 3 O 4 @polydopamine nanoparticle-loaded natural killer cells suggest a promising anticancer treatment . Biomaterials Science 6:10, pages 2714-2725.
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Feifei Yang, Rong Wang, Wenli Feng, Chong Chen, Xiao Yang, Lina Wang, Yuting Hu, Qian Ren & Guoguang Zheng. (2018) Characteristics of NK cells from leukemic microenvironment in MLL-AF9 induced acute myeloid leukemia. Molecular Immunology 93, pages 68-78.
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Sabine Galland, Joanna Vuille, Patricia Martin, Igor Letovanec, Anne Caignard, Giulia Fregni & Ivan Stamenkovic. (2017) Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets. Cell Reports 20:12, pages 2891-2905.
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Merav E Shaul & Zvi G Fridlender. (2017) Neutrophils as active regulators of the immune system in the tumor microenvironment. Journal of Leukocyte Biology 102:2, pages 343-349.
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YAO YUAN, YU-CHEN JIANG, CHONG-KUI SUN & QIAN-MING CHEN. (2016) Role of the tumor microenvironment in tumor progression and the clinical applications (Review). Oncology Reports 35:5, pages 2499-2515.
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Yingbin Luo, Jianchun Wu, Xiaowen Zhu, Chenyuan Gong, Chao Yao, Zhongya Ni, Lixin Wang, Lulu Ni, Yan Li & Shiguo Zhu. (2016) NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula. Mediators of Inflammation 2016, pages 1-7.
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Peng Xiong, Hai-Wei Sang & Min Zhu. (2015) Critical roles of co-activation receptor DNAX accessory molecule-1 in natural killer cell immunity. Immunology 146:3, pages 369-378.
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Gang Deng, Xiaodong Zheng, Jing Zhou, Haiming Wei, Zhigang Tian & Rui Sun. (2015) Generation and Preclinical Characterization of an NKp80-Fc Fusion Protein for Redirected Cytolysis of Natural Killer (NK) Cells against Leukemia. Journal of Biological Chemistry 290:37, pages 22474-22484.
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Juan P. Cata, Claudius Conrad & Katy Rezvani. (2015) Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes. Scientifica 2015, pages 1-8.
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Anne-Sophie Chretien, Aude Le Roy, Norbert Vey, Thomas Prebet, Didier Blaise, Cyril Fauriat & Daniel Olive. (2014) Cancer-Induced Alterations of NK-Mediated Target Recognition: Current and Investigational Pharmacological Strategies Aiming at Restoring NK-Mediated Anti-Tumor Activity. Frontiers in Immunology 5.
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W.H. Fridman, R. Remark, J. Goc, N.A. Giraldo, E. Becht, Scott A. Hammond, D. Damotte, M.-C. Dieu-Nosjean & Catherine Sautès-Fridman. (2014) The Immune Microenvironment: A Major Player in Human Cancers. International Archives of Allergy and Immunology 164:1, pages 13-26.
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Richa Sharma & Asmita Das. (2013) Organ-specific phenotypic and functional features of NK cells in humans. Immunologic Research 58:1, pages 125-131.
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Marlies E Heuvers, Joachim G Aerts, Robin Cornelissen, Harry Groen, Henk C Hoogsteden & Joost P Hegmans. (2012) Patient-tailored modulation of the immune system may revolutionize future lung cancer treatment. BMC Cancer 12:1.
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