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OncoImmunology Volume 2, 2013 - Issue 5

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Multifunctional γδ T cells and their receptors for targeted anticancer immunotherapy

Wouter Scheper Department of Hematology and Immunology; University Medical Center; Utrecht, The Netherlands

Cordula Gründer Department of Hematology and Immunology; University Medical Center; Utrecht, The Netherlands

Jürgen Kuball Department of Hematology and Immunology; University Medical Center; Utrecht, The NetherlandsCorrespondence[email protected]

Article: e23974 | Received 06 Feb 2013, Accepted 12 Feb 2013, Published online: 01 May 2013

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https://doi.org/10.4161/onci.23974

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Ronja Pscheid, Esther Drent, Judith Wienke, Josephine G. M. Strijker, Mark Throsby & Jan J. Molenaar. (2023) Three-Dimensional Modeling of Solid Tumors and Their Microenvironment to Evaluate T Cell Therapy Efficacy In Vitro. The Journal of Immunology 211:2, pages 229-240.
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Jiamian Zheng, Dan Qiu, Xuan Jiang, Yun Zhao, Haotian Zhao, Xiaofang Wu, Jie Chen, Jing Lai, Wenbin Zhang, Xutong Li, Yangqiu Li, Xiuli Wu & Zhenyi Jin. (2022) Increased PD-1+Foxp3+ γδ T cells associate with poor overall survival for patients with acute myeloid leukemia. Frontiers in Oncology 12.
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Anke Janssen, Eline van Diest, Anna Vyborova, Lenneke Schrier, Anke Bruns, Zsolt Sebestyen, Trudy Straetemans, Moniek de Witte & Jürgen Kuball. (2022) The Role of γδ T Cells as a Line of Defense in Viral Infections after Allogeneic Stem Cell Transplantation: Opportunities and Challenges. Viruses 14:1, pages 117.
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Josephine G. M. Strijker, Ronja Pscheid, Esther Drent, Jessica J. F. van der Hoek, Bianca Koopmans, Kimberley Ober, Sander R. van Hooff, Waleed M. Kholosy, Annelisa M. Cornel, Chris Coomans, Andrea Bisso, Marleen M. van Loenen, Jan J. Molenaar & Judith Wienke. (2021) αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression. Journal of Personalized Medicine 11:9, pages 923.
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Anna Vyborova, Dennis X. Beringer, Domenico Fasci, Froso Karaiskaki, Eline van Diest, Lovro Kramer, Aram de Haas, Jasper Sanders, Anke Janssen, Trudy Straetemans, Daniel Olive, Jeanette Leusen, Lola Boutin, Steven Nedellec, Samantha L. Schwartz, Michael J. Wester, Keith A. Lidke, Emmanuel Scotet, Diane S. Lidke, Albert J.R. Heck, Zsolt Sebestyen & Jürgen Kuball. (2020) γ9δ2T cell diversity and the receptor interface with tumor cells. Journal of Clinical Investigation 130:9, pages 4637-4651.
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Zsolt Sebestyen, Immo Prinz, Julie Déchanet-Merville, Bruno Silva-Santos & Jurgen Kuball. (2019) Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies. Nature Reviews Drug Discovery 19:3, pages 169-184.
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José Rivera-Torres & Esther San José. (2019) Src Tyrosine Kinase Inhibitors: New Perspectives on Their Immune, Antiviral, and Senotherapeutic Potential. Frontiers in Pharmacology 10.
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Trudy Straetemans, Guido J. J. Kierkels, Ruud Doorn, Koen Jansen, Sabine Heijhuurs, Joao M. dos Santos, Anna D. D. van Muyden, Henri Vie, Béatrice Clemenceau, Reinier Raymakers, Moniek de Witte, Zsolt Sebestyén & Jürgen Kuball. (2018) GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR. Frontiers in Immunology 9.
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Vito Pistoia, Nicola Tumino, Paola Vacca, Irene Veneziani, Alessandro Moretta, Franco Locatelli & Lorenzo Moretta. (2018) Human γδ T-Cells: From Surface Receptors to the Therapy of High-Risk Leukemias. Frontiers in Immunology 9.
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Camille Khairallah, Julie D?chanet-Merville & Myriam Capone. (2017) ?? T Cell-Mediated Immunity to Cytomegalovirus Infection. Frontiers in Immunology 8.
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W Scheper, C Gründer, T Straetemans, Z Sebestyen & J Kuball. (2013) Hunting for clinical translation with innate-like immune cells and their receptors. Leukemia 28:6, pages 1181-1190.
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