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Arming NK cells with enhanced antitumor activity

CARs and beyond

&
Article: e25220 | Received 29 May 2013, Accepted 29 May 2013, Published online: 10 Jun 2013

Keep up to date with the latest research on this topic with citation updates for this article.

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Jian Gao, Zhaojun Duan, Ling Zhang, Xiangbo Huang, Lu Long, Jing Tu, Hua Liang, Yu Zhang, Tao Shen & Fengmin Lu. (2016) Failure recovery of circulating NKG2D+CD56dimNK cells in HBV-associated hepatocellular carcinoma after hepatectomy predicts early recurrence. OncoImmunology 5:1.
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Panagiotis Tsirigotis, Avichai Shimoni & Arnon Nagler. (2014) The expanding horizon of immunotherapy in the treatment of malignant disorders: Allogeneic hematopoietic stem cell transplantation and beyond. Annals of Medicine 46:6, pages 384-396.
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Assaf Marcus & Zelig Eshhar. (2014) Allogeneic chimeric antigen receptor-modified cells for adoptive cell therapy of cancer. Expert Opinion on Biological Therapy 14:7, pages 947-954.
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Elisabetta Cariani & Gabriele Missale. (2013) KIR/HLA immunogenetic background influences the evolution of hepatocellular carcinoma. OncoImmunology 2:12.
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Karol Sadowski, Wioletta Olejarz & Grzegorz Basak. (2022) Modern Advances in CARs Therapy and Creating a New Approach to Future Treatment. International Journal of Molecular Sciences 23:23, pages 15006.
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Dayane Schmidt, Sima Ebrahimabadi, Kauan Ribeiro de Sena Gomes, Graziela de Moura Aguiar, Mariane Cariati Tirapelle, Renata Nacasaki Silvestre, Júlia Teixeira Cottas de Azevedo, Dimas Tadeu Covas & Virginia Picanço-Castro. (2022) Engineering CAR-NK cells: how to tune innate killer cells for cancer immunotherapy. Immunotherapy Advances 2:1.
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Faroogh Marofi, Heshu Sulaiman Rahman, Lakshmi Thangavelu, Aleksey Dorofeev, Favian Bayas-Morejón, Naghmeh Shirafkan, Navid Shomali, Max Stanley Chartrand, Mostafa Jarahian, Ghasem Vahedi, Rebar N. Mohammed, Somayeh Shahrokh, Morteza Akbari & Farhad Motavalli Khiavi. (2021) Renaissance of armored immune effector cells, CAR-NK cells, brings the higher hope for successful cancer therapy. Stem Cell Research & Therapy 12:1.
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Pranav Oberoi, Kathrina Kamenjarin, Jose Francisco Villena Ossa, Barbara Uherek, Halvard Bönig & Winfried S. Wels. (2020) Directed Differentiation of Mobilized Hematopoietic Stem and Progenitor Cells into Functional NK Cells with Enhanced Antitumor Activity. Cells 9:4, pages 811.
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Laura Sanz-Ortega, José M. Rojas, Yadileiny Portilla, Sonia Pérez-Yagüe & Domingo F. Barber. (2019) Magnetic Nanoparticles Attached to the NK Cell Surface for Tumor Targeting in Adoptive Transfer Therapies Does Not Affect Cellular Effector Functions. Frontiers in Immunology 10.
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Ping Zhang, Songbo Zhao, Chao Wu, Jialu Li, Zixuan Li, Chunmei Wen, Siyi Hu, Gangli An, Huimin Meng, Xingding Zhang & Lin Yang. (2018) Effects of CSF1R-targeted chimeric antigen receptor-modified NK92MI & T cells on tumor-associated macrophages. Immunotherapy 10:11, pages 935-949.
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Huimin Meng, Xue Sun, Yanhui Song, Jianxuan Zou, Gangli An, Zeming Jin & Lin Yang. (2018) La/SSB chimeric autoantibody receptor modified NK92MI cells for targeted therapy of autoimmune disease. Clinical Immunology 192, pages 40-49.
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Lucía Fernández, Jean-Yves Metais, Adela Escudero, María Vela, Jaime Valentín, Isabel Vallcorba, Alejandra Leivas, Juan Torres, Antonio Valeri, Ana Patiño-García, Joaquín Martínez, Wing Leung & Antonio Pérez-Martínez. (2017) Memory T Cells Expressing an NKG2D-CAR Efficiently Target Osteosarcoma Cells. Clinical Cancer Research 23:19, pages 5824-5835.
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Ying Chen, Fengtao You, Licui Jiang, Jialu Li, Xuejun Zhu, Yangyi Bao, Xiang Sun, Xiaowen Tang, Huimin Meng, Gangli An, Bozhen Zhang & Lin Yang. (2017) Gene-modified NK-92MI cells expressing a chimeric CD16-BB-ζ or CD64-BB-ζ receptor exhibit enhanced cancer-killing ability in combination with therapeutic antibody. Oncotarget 8:23, pages 37128-37139.
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Fang Fang, Weihua Xiao & Zhigang Tian. (2017) NK cell-based immunotherapy for cancer. Seminars in Immunology 31, pages 37-54.
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Congcong Zhang, Pranav Oberoi, Sarah Oelsner, Anja Waldmann, Aline Lindner, Torsten Tonn & Winfried S. Wels. (2017) Chimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor Immunity. Frontiers in Immunology 8.
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Ho-Young Park, Taek Joon Yoon, Wookyung Lee, Yoonsook Kim & Hee-Don Choi. (2017) Antimetastatic effect of glycoprotein isolated from rice bran on colon 26-M3.1 cell line. Journal of Functional Foods 32, pages 278-284.
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Gabriella Pietra, Chiara Vitale, Daniela Pende, Alice Bertaina, Francesca Moretta, Michela Falco, Paola Vacca, Elisa Montaldo, Claudia Cantoni, Maria Cristina Mingari, Alessandro Moretta, Franco Locatelli & Lorenzo Moretta. (2015) Human natural killer cells: news in the therapy of solid tumors and high-risk leukemias. Cancer Immunology, Immunotherapy 65:4, pages 465-476.
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Fan Yang, Hao Jin, Jian Wang, Qian Sun, Cihui Yan, Feng Wei & Xiubao Ren. 2016. Progress in Cancer Immunotherapy. Progress in Cancer Immunotherapy 169 239 .
Claudia Cantoni, Korneel Grauwet, Gabriella Pietra, Monica Parodi, Maria Cristina Mingari, Andrea De Maria, Herman Favoreel & Massimo Vitale. (2015) Role of NK cells in immunotherapy and virotherapy of solid tumors. Immunotherapy 7:8, pages 861-882.
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Kurt Schönfeld, Christiane Sahm, Congcong Zhang, Sonja Naundorf, Christian Brendel, Marcus Odendahl, Paulina Nowakowska, Halvard Bönig, Ulrike Köhl, Stephan Kloess, Sylvia Köhler, Heidi Holtgreve-Grez, Anna Jauch, Manfred Schmidt, Ralf Schubert, Klaus Kühlcke, Erhard Seifried, Hans G Klingemann, Michael A Rieger, Torsten Tonn, Manuel Grez & Winfried S Wels. (2015) Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor. Molecular Therapy 23:2, pages 330-338.
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Cristina Eguizabal, Olatz Zenarruzabeitia, Jorge Monge, Silvia Santos, Miguel Angel Vesga, Natalia Maruri, Arantza Arrieta, Marta Riñón, Estibaliz Tamayo-Orbegozo, Laura Amo, Susana Larrucea & Francisco Borrego. (2014) Natural Killer Cells for Cancer Immunotherapy: Pluripotent Stem Cells-Derived NK Cells as an Immunotherapeutic Perspective. Frontiers in Immunology 5.
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