742
Views
55
CrossRef citations to date
0
Altmetric
Review

Wnt signaling in lung organogenesis

&
Pages 100-108 | Published online: 11 Jun 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Cliff R. Rims & John K. McGuire. (2014) Matrilysin (MMP-7) catalytic activity regulates β-catenin localization and signaling activation in lung epithelial cells. Experimental Lung Research 40:3, pages 126-136.
Read now

Articles from other publishers (53)

Yunpeng Ge, Yitian Liu, Bo Ji, Yang Fang, Yana Xie, Reiko Sakurai, Jiajia Wang, Ziyue Zhang, Yifei Wang, Xu Wang & Virender K. Rehan. (2023) Evidence for Wnt signaling’s central involvement in perinatal nicotine exposure-induced offspring lung pathology and its modulation by electroacupuncture. Biomedicine & Pharmacotherapy 168, pages 115824.
Crossref
Zachary E. Easton, Timothy R.H. Regnault, Martina Mudri, Shuang Zhao, Shane A. Smith, Adrianna Zardini Buzatto, Janet Li, Ryan Duruisseau-Kuntz, Jacob Davidson, Liang Li & Andreana Bütter. (2023) The metabolic and lipidomic profiling of the effects of tracheal occlusion in a rabbit model of congenital diaphragmatic hernia. Journal of Pediatric Surgery 58:5, pages 971-980.
Crossref
Xin Wang, Xianglin Hou, Yannan Zhao, Ruiming Zhao, Jianwu Dai, Huaping Dai & Chen Wang. (2023) The early and late intervention effects of collagen-binding FGF2 on elastase-induced lung injury. Biomedicine & Pharmacotherapy 158, pages 114147.
Crossref
Kerin M. Cahill, Trenton K. Johnson, Zakia Perveen, Matthew Schexnayder, Rui Xiao, Linda M. Heffernan, Ingeborg M. Langohr, Daniel B. Paulsen, Arthur L. Penn & Alexandra Noël. (2022) In utero exposures to mint-flavored JUUL aerosol impair lung development and aggravate house dust mite-induced asthma in adult offspring mice. Toxicology 477, pages 153272.
Crossref
Nancy W. Lin, Cuining Liu, Ivana V. Yang, Lisa A. Maier, Dawn L. DeMeo, Cheyret Wood, Shuyu Ye, Margaret H. Cruse, Vong L. Smith, Carrie A. Vyhlidal, Katerina Kechris & Sunita Sharma. (2022) Sex-Specific Differences in MicroRNA Expression During Human Fetal Lung Development. Frontiers in Genetics 13.
Crossref
Rashika Joshi, Matthew R. Batie, Qiang Fan & Brian M. Varisco. (2022) Mouse lung organoid responses to reduced, increased, and cyclic stretch. American Journal of Physiology-Lung Cellular and Molecular Physiology 322:1, pages L162-L173.
Crossref
Anthony P. Brown, Lucy Cai, Benjamin I. Laufer, Lisa A. Miller, Janine M. LaSalle & Hong Ji. (2022) Long-term effects of wildfire smoke exposure during early life on the nasal epigenome in rhesus macaques. Environment International 158, pages 106993.
Crossref
Hanife Guler Donmez, Hasan Tolga Celik, Gozdem Kayki, Atakan Tanacan, Murat Cagan, Sule Yigit, Murat Yurdakok, Ayse Nur Cakar & Mehmet Sinan Beksac. (2021) Impact of Prematurity on the Buccal Epithelial Cells of the Neonates via Wnt/Beta-Catenin Signaling Pathway and Apoptosis. American Journal of Perinatology.
Crossref
Elena N. Huang, Henry Quach, Jin-A Lee, Joshua Dierolf, Theo J. Moraes & Amy P. Wong. (2021) A Developmental Role of the Cystic Fibrosis Transmembrane Conductance Regulator in Cystic Fibrosis Lung Disease Pathogenesis. Frontiers in Cell and Developmental Biology 9.
Crossref
Roopa Siddaiah, Christiana N. Oji-Mmuo, Deborah T. Montes, Nathalie Fuentes, Debra Spear, Ann Donnelly & Patricia Silveyra. (2021) MicroRNA Signatures Associated with Bronchopulmonary Dysplasia Severity in Tracheal Aspirates of Preterm Infants. Biomedicines 9:3, pages 257.
Crossref
Dorota Anusewicz, Magdalena Orzechowska & Andrzej K. Bednarek. (2020) Lung squamous cell carcinoma and lung adenocarcinoma differential gene expression regulation through pathways of Notch, Hedgehog, Wnt, and ErbB signalling. Scientific Reports 10:1.
Crossref
Swati Uniyal, Amit Kumar Tyagi & Jai Prakash Muyal. (2020) All Trans Retinoic Acid (ATRA) progresses alveolar epithelium regeneration by involving diverse signalling pathways in emphysematous rat. Biomedicine & Pharmacotherapy 131, pages 110725.
Crossref
Willy Roque, Alexandra Boni, Jose Martinez-Manzano & Freddy Romero. (2020) A Tale of Two Proteolytic Machines: Matrix Metalloproteinases and the Ubiquitin–Proteasome System in Pulmonary Fibrosis. International Journal of Molecular Sciences 21:11, pages 3878.
Crossref
Alexandra Noël, Shannon Hansen, Anusha Zaman, Zakia Perveen, Rakeysha Pinkston, Ekhtear Hossain, Rui Xiao & Arthur Penn. (2020) In utero exposures to electronic-cigarette aerosols impair the Wnt signaling during mouse lung development . American Journal of Physiology-Lung Cellular and Molecular Physiology 318:4, pages L705-L722.
Crossref
Aravind Sivakumar & David B. Frank. (2019) Paradigms That Define Lung Epithelial Progenitor Cell Fate in Development and Regeneration. Current Stem Cell Reports 5:4, pages 133-144.
Crossref
Yves Lecarpentier, Elizabeth Gourrier, Vincent Gobert & Alexandre Vallée. (2019) Bronchopulmonary Dysplasia: Crosstalk Between PPARγ, WNT/β-Catenin and TGF-β Pathways; The Potential Therapeutic Role of PPARγ Agonists. Frontiers in Pediatrics 7.
Crossref
Martina Mudri, Shane A. Smith, Christina Vanderboor, Jacob Davidson, Timothy R.H. Regnault & Andreana Bütter. (2019) The effects of tracheal occlusion on Wnt signaling in a rabbit model of congenital diaphragmatic hernia. Journal of Pediatric Surgery 54:5, pages 937-944.
Crossref
Diptiman Chanda, Eva Otoupalova, Samuel R. Smith, Thomas Volckaert, Stijn P. De Langhe & Victor J. Thannickal. (2019) Developmental pathways in the pathogenesis of lung fibrosis. Molecular Aspects of Medicine 65, pages 56-69.
Crossref
Matthew R. Jones, Salma Dilai, Arun Lingampally, Cho-Ming Chao, Soula Danopoulos, Gianni Carraro, Regina Mukhametshina, Jochen Wilhelm, Eveline Baumgart-Vogt, Denise Al Alam, Chengshui Chen, Parviz Minoo, Jin San Zhang & Saverio Bellusci. (2019) A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis. Frontiers in Genetics 9.
Crossref
Daniel T. Malleske, Don HayesJr.Jr., Scott W. Lallier, Cynthia L. Hill & Susan D. Reynolds. (2018) Regulation of Human Airway Epithelial Tissue Stem Cell Differentiation by β-Catenin, P300, and CBP. Stem Cells 36:12, pages 1905-1916.
Crossref
Wioletta Skronska-Wasek, Reinoud Gosens, Melanie Königshoff & Hoeke Abele Baarsma. (2018) WNT receptor signalling in lung physiology and pathology. Pharmacology & Therapeutics 187, pages 150-166.
Crossref
Dickson W.L. Wong, Wai Han Yiu, Kam Wa Chan, Ye Li, Bin Li, Sarah W.Y. Lok, Makoto M. Taketo, Peter Igarashi, Loretta Y.Y. Chan, Joseph C.K. Leung, Kar Neng Lai & Sydney C.W. Tang. (2018) Activated renal tubular Wnt/β-catenin signaling triggers renal inflammation during overload proteinuria. Kidney International 93:6, pages 1367-1383.
Crossref
Poulomi Banerjee, Harshini Surendran, Kapil Bharti, Kaoru Morishita, Anurag Varshney & Rajarshi Pal. (2018) Long Noncoding RNA RP11-380D23.2 Drives Distal-Proximal Patterning of the Lung by Regulating PITX2 Expression. Stem Cells 36:2, pages 218-229.
Crossref
Yan LiMichael H. ChoXiaobo Zhou. (2017) What do polymorphisms tell us about the mechanisms of COPD?. Clinical Science 131:24, pages 2847-2863.
Crossref
Judit Rapp, Luca Jaromi, Krisztian Kvell, Gyorgy Miskei & Judit E. Pongracz. (2017) WNT signaling – lung cancer is no exception. Respiratory Research 18:1.
Crossref
H A Baarsma & M Königshoff. (2017) ‘WNT-er is coming’ : WNT signalling in chronic lung diseases . Thorax 72:8, pages 746-759.
Crossref
Uchenna Unachukwu, Jordis Trischler, Monica Goldklang, Rui Xiao & Jeanine D'Armiento. (2017) Maternal smoke exposure decreases mesenchymal proliferation and modulates Rho‐GTPase‐dependent actin cytoskeletal signaling in fetal lungs. The FASEB Journal 31:6, pages 2340-2351.
Crossref
Peter Walentek & Ian K. Quigley. (2017) What we can learn from a tadpole about ciliopathies and airway diseases: Using systems biology in Xenopus to study cilia and mucociliary epithelia . genesis 55:1-2, pages e23001.
Crossref
Soula DanopoulosMichael KrainockOmar ToubatMatthew Thornton, Brendan Grubbs & Denise Al Alam. (2016) Rac1 modulates mammalian lung branching morphogenesis in part through canonical Wnt signaling. American Journal of Physiology-Lung Cellular and Molecular Physiology 311:6, pages L1036-L1049.
Crossref
Briana R. Dye, Alyssa J. Miller & Jason R. Spence. (2016) How to Grow a Lung: Applying Principles of Developmental Biology to Generate Lung Lineages from Human Pluripotent Stem Cells. Current Pathobiology Reports 4:2, pages 47-57.
Crossref
Hengning Ke, Katarzyna Chmielarska Masoumi, Kristofer Ahlqvist, Michael J. Seckl, Kristina Rydell-Törmänen & Ramin Massoumi. (2016) Nemo-like kinase regulates the expression of vascular endothelial growth factor (VEGF) in alveolar epithelial cells. Scientific Reports 6:1.
Crossref
Annika Andersson-Sjöland, Jenny C Karlsson & Kristina Rydell-Törmänen. (2016) ROS-induced endothelial stress contributes to pulmonary fibrosis through pericytes and Wnt signaling. Laboratory Investigation 96:2, pages 206-217.
Crossref
Wei Xu, Ying Zhao, Binglun Zhang, Bo Xu, Yang Yang, Yujing Wang & Chunfeng Liu. (2015) Wnt3a Mediates the Inhibitory Effect of Hyperoxia on the Transdifferentiation of AECIIs to AECIs. Journal of Histochemistry & Cytochemistry 63:11, pages 879-891.
Crossref
Changgong Li, Saverio Bellusci, Zea Borok & Parviz Minoo. (2015) Non-canonical WNT signalling in the lung. Journal of Biochemistry 158:5, pages 355-365.
Crossref
MINGZHAN DU, FENG SHI, HAI ZHANG, SHUKAI XIA, MIN ZHANG, JUAN MA, XIAOMING BAI, LI ZHANG, YIPIN WANG, SHANYU CHENG, QINYI YANG & JING LENG. (2015) Prostaglandin E2 promotes human cholangiocarcinoma cell proliferation, migration and invasion through the upregulation of β-catenin expression via EP3-4 receptor. Oncology Reports 34:2, pages 715-726.
Crossref
Wei Liu, Dan-Dan Yi, Jian-Li Guo, Zhu-Xing Xiang, Lin-Feng Deng & Lei He. (2015) Nuciferine, extracted from Nelumbo nucifera Gaertn, inhibits tumor-promoting effect of nicotine involving Wnt/?-catenin signaling in non-small cell lung cancer. Journal of Ethnopharmacology 165, pages 83-93.
Crossref
Tomoyo Sasaki & Michael Kahn. (2014) Inhibition of β-catenin/p300 interaction proximalizes mouse embryonic lung epithelium. Translational Respiratory Medicine 2:1.
Crossref
Weiliang XieThomas J. LynchXiaoming LiuScott R. TylerShuyang Yu, Xinyuan ZhouMeihui LuoDavid M. KusnerXingshen SunYaling YiYulong ZhangMichael J. GoodheartKalpaj R. ParekhJames M. WellsHai-Hui XueLarysa H. Pevny & John F. Engelhardt. (2014) Sox2 modulates Lef-1 expression during airway submucosal gland development . American Journal of Physiology-Lung Cellular and Molecular Physiology 306:7, pages L645-L660.
Crossref
Changgong Li, Aimin Li, Yiming Xing, Min Li, Belinda Chan, Ruoyun Ouyang, Makoto Mark Taketo, Raju Kucherlapati, Zea Borok & Parviz Minoo. (2013) Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling. Developmental Biology 378:1, pages 13-24.
Crossref
Tamilla Nechiporuk, Olga Klezovitch, Liem Nguyen & Valeri Vasioukhin. (2013) Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. Developmental Biology 377:2, pages 375-384.
Crossref
Harikrishna Tanjore, Amber L. Degryse, Peter F. Crossno, Xiaochuan C. Xu, Melinda E. McConaha, Brittany R. Jones, Vasiliy V. Polosukhin, Andrew J. Bryant, Dong-Sheng Cheng, Dawn C. Newcomb, Frank B. McMahon, Linda A. Gleaves, Timothy S. Blackwell & William E. Lawson. (2013) β-Catenin in the Alveolar Epithelium Protects from Lung Fibrosis after Intratracheal Bleomycin. American Journal of Respiratory and Critical Care Medicine 187:6, pages 630-639.
Crossref
Mingfeng Zhang, Jueping Shi, Yide Huang & Laijun Lai. (2012) Expression of canonical WNT/β-CATENIN signaling components in the developing human lung. BMC Developmental Biology 12:1.
Crossref
Russell W. Smith, Douglas A. Hicks & Susan D. Reynolds. (2012) Roles for β-Catenin and Doxycycline in the Regulation of Respiratory Epithelial Cell Frequency and Function. American Journal of Respiratory Cell and Molecular Biology 46:1, pages 115-124.
Crossref
Denise Al Alam, Melissa Green, Reza Tabatabai Irani, Sara Parsa, Soula Danopoulos, Frederic G. Sala, Jonathan Branch, Elie El Agha, Caterina Tiozzo, Robert Voswinckel, Edwin C. Jesudason, David Warburton & Saverio Bellusci. (2011) Contrasting Expression of Canonical Wnt Signaling Reporters TOPGAL, BATGAL and Axin2LacZ during Murine Lung Development and Repair. PLoS ONE 6:8, pages e23139.
Crossref
Yan-ping Xu, Jia-jun Zhu, Fen Cheng, Ke-wen Jiang, Wei-zhong Gu, Zheng Shen, Yi-dong Wu, Li Liang & Li-zhong Du. (2011) Ghrelin ameliorates hypoxia-induced pulmonary hypertension via phospho-GSK3β/β-catenin signaling in neonatal rats. Journal of Molecular Endocrinology 47:1, pages 33-43.
Crossref
Yuru Liu, Ruxana T. Sadikot, Guy R. Adami, Vladimir V. Kalinichenko, Srikanth Pendyala, Viswanathan Natarajan, You-yang Zhao & Asrar B. Malik. (2011) FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa . Journal of Experimental Medicine 208:7, pages 1473-1484.
Crossref
Heather M. Brechbuhl, Moumita Ghosh, Mary Kathryn Smith, Russell W. Smith, Bilan Li, Douglas A. Hicks, Brook B. Cole, Paul R. Reynolds & Susan D. Reynolds. (2011) β-Catenin Dosage Is a Critical Determinant of Tracheal Basal Cell Fate Determination. The American Journal of Pathology 179:1, pages 367-379.
Crossref
Rui Wang, Joumana Ahmed, Guoqing Wang, Ibrahim Hassan, Yael Strulovici-Barel, Neil R. Hackett & Ronald G. Crystal. (2011) Down-Regulation of the Canonical Wnt β-Catenin Pathway in the Airway Epithelium of Healthy Smokers and Smokers with COPD. PLoS ONE 6:4, pages e14793.
Crossref
John N. MainaJohn N. Maina. 2011. Bioengineering Aspects in the Design of Gas Exchangers. Bioengineering Aspects in the Design of Gas Exchangers 141 221 .
John N. MainaJohn N. Maina. 2011. Bioengineering Aspects in the Design of Gas Exchangers. Bioengineering Aspects in the Design of Gas Exchangers 85 140 .
Anna Ferrer-Vaquer, Anna Piliszek, Guangnan Tian, Robert J Aho, Daniel Dufort & Anna-Katerina Hadjantonakis. (2010) A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse. BMC Developmental Biology 10:1.
Crossref
Riitta Kaarteenaho, Elisa Lappi-Blanco & Siri Lehtonen. (2010) Epithelial N-cadherin and nuclear β-catenin are up-regulated during early development of human lung. BMC Developmental Biology 10:1.
Crossref
Jorge Correia-Pinto, S?lvia Gonzaga, Yadi Huang & Robbert Rottier. (2010) Congenital lung lesions?underlying molecular mechanisms. Seminars in Pediatric Surgery 19:3, pages 171-179.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.