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Prion Volume 2, 2008 - Issue 2
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Commentary & View

The irreversible binding of amyloid peptide substrates to insulin-degrading enzyme

A biological perspective

Matías B. de Tullio Fundación Instituto Leloir-Instituto de Investigaciones Bioquímicas de Buenos Aires
,
Laura Morelli Fundación Instituto Leloir-Instituto de Investigaciones Bioquímicas de Buenos Aires
&
Eduardo M. Castaño Fundación Instituto Leloir-Instituto de Investigaciones Bioquímicas de Buenos Aires
Pages 51-56 | Received 03 Jul 2008, Accepted 31 Jul 2008, Published online: 01 Oct 2008

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Grazia R. Tundo, Diego Sbardella, Chiara Ciaccio, Giuseppe Grasso, Magda Gioia, Andrea Coletta, Fabio Polticelli, Donato Di Pierro, Danilo Milardi, Peter Van Endert, Stefano Marini & Massimo Coletta. (2017) Multiple functions of insulin-degrading enzyme: a metabolic crosslight?. Critical Reviews in Biochemistry and Molecular Biology 52:5, pages 554-582.
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J Lasierra-Cirujeda, P Coronel, MJ Aza & M Gimeno. (2013) Beta-amyloidolysis and glutathione in Alzheimer’s disease. Journal of Blood Medicine 4, pages 31-38.
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Articles from other publishers (19)

Shobha Kumari, Jayant Singh Bhardwaj, Sanskruti Santosh Kharavtekar, Deepika Grewal, Shreyasi Ghosh Ray, Abhay Bhardwaj, Sunil Kumar Dubey, Prashant Kesharwani, Taruna Arora & Rajeev Taliyan. 2023. Nanomedicine-Based Approaches for the Treatment of Dementia. Nanomedicine-Based Approaches for the Treatment of Dementia 265 294 .
Karina Abramov-Harpaz & Yifat Miller. (2022) Insights into Non-Proteolytic Inhibitory Mechanisms of Polymorphic Early-Stage Amyloid β Oligomers by Insulin Degrading Enzyme. Biomolecules 12:12, pages 1886.
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Laetitia Lesire, Florence Leroux, Rebecca Deprez-Poulain & Benoit Deprez. (2022) Insulin-Degrading Enzyme, an Under-Estimated Potential Target to Treat Cancer?. Cells 11:7, pages 1228.
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Luís Sousa, Mariana Guarda, Maria João Meneses, M Paula Macedo & Hugo Vicente Miranda. (2021) Insulin‐degrading enzyme: an ally against metabolic and neurodegenerative diseases. The Journal of Pathology 255:4, pages 346-361.
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Bhargavi Ramaraju, Spencer L. Nelson, Wenwei Zheng, Rodolfo Ghirlando & Lalit Deshmukh. (2021) Quantitative NMR Study of Insulin-Degrading Enzyme Using Amyloid-β and HIV-1 p6 Elucidates Its Chaperone Activity. Biochemistry 60:33, pages 2519-2523.
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Hans-Gert Bernstein, Gerburg Keilhoff, Henrik Dobrowolny & Johann Steiner. (2019) Binding varicella zoster virus: an underestimated facet of insulin-degrading enzyme´s implication for Alzheimer´s disease pathology?. European Archives of Psychiatry and Clinical Neuroscience 270:4, pages 495-496.
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Igor V. Kurochkin, Enrico Guarnera & Igor N. Berezovsky. (2018) Insulin-Degrading Enzyme in the Fight against Alzheimer’s Disease. Trends in Pharmacological Sciences 39:1, pages 49-58.
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Komal Panchal, Ajay Kumar & Anand K. Tiwari. 2018. HSP70 in Human Diseases and Disorders. HSP70 in Human Diseases and Disorders 3 35 .
Melissa A. Schilling. (2016) Unraveling Alzheimer’s: Making Sense of the Relationship between Diabetes and Alzheimer’s Disease1. Journal of Alzheimer's Disease 51:4, pages 961-977.
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Joaquín Lasierra-Cirujeda, María José Aza Pascual-Salcedo & María Mercedes Aza Pascual-Salcedo. (2016) Sulodexide and Alzheimer’s Disease: A Preliminary Prospective Study. World Journal of Cardiovascular Diseases 06:02, pages 54-71.
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Sandeep K. Sharma, Erik Chorell & Pernilla Wittung-Stafshede. (2015) Insulin-degrading enzyme is activated by the C-terminus of ?-synuclein. Biochemical and Biophysical Research Communications 466:2, pages 192-195.
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Ekaterina G. Kochkina, Svetlana A. Plesneva, Dmitrii S. Vasilev, Igor A. Zhuravin, Anthony J. Turner & Natalia N. Nalivaeva. (2015) Effects of ageing and experimental diabetes on insulin-degrading enzyme?expression?in male rat tissues. Biogerontology 16:4, pages 473-484.
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Sandeep K. Sharma, Erik Chorell, Pär Steneberg, Emma Vernersson-Lindahl, Helena Edlund & Pernilla Wittung-Stafshede. (2015) Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner. Scientific Reports 5:1.
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Diego Sbardella, Grazia Raffaella Tundo, Francesca Sciandra, Manuela Bozzi, Magda Gioia, Chiara Ciaccio, Umberto Tarantino, Andrea Brancaccio, Massimo Coletta & Stefano Marini. (2015) Proteasome Activity Is Affected by Fluctuations in Insulin-Degrading Enzyme Distribution. PLOS ONE 10:7, pages e0132455.
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Clémentine Beuzelin, Irini Evnouchidou, Pascal Rigolet, Anne Cauvet-Burgevin, Pierre-Marie Girard, Delphine Dardalhon, Slobodan Culina, Abdelaziz Gdoura, Peter van Endert & Stefania Francesconi. (2013) Deletion of the Fission Yeast Homologue of Human Insulinase Reveals a TORC1-Dependent Pathway Mediating Resistance to Proteotoxic Stress. PLoS ONE 8:6, pages e67705.
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Matias B. de Tullio, Valeria Castelletto, Ian W. Hamley, Pamela V. Martino Adami, Laura Morelli & Eduardo M. Casta?o. (2013) Proteolytically Inactive Insulin-Degrading Enzyme Inhibits Amyloid Formation Yielding Non-Neurotoxic A? Peptide Aggregates. PLoS ONE 8:4, pages e59113.
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Grazia Raffaella Tundo, Diego Sbardella, Chiara Ciaccio, Antonio Bianculli, Augusto Orlandi, Maria Giovanna Desimio, Gaetano Arcuri, Massimiliano Coletta & Stefano Marini. (2013) Insulin-degrading Enzyme (IDE). Journal of Biological Chemistry 288:4, pages 2281-2289.
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María C. Leal & Laura Morelli. 2013. Handbook of Proteolytic Enzymes. Handbook of Proteolytic Enzymes 1415 1420 .
John E. Morley. (2010) Nutrition and the Brain. Clinics in Geriatric Medicine 26:1, pages 89-98.
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