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Prion Volume 7, 2013 - Issue 5
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Research Paper

PrP mRNA and protein expression in brain and PrPc in CSF in Creutzfeldt-Jakob disease MM1 and VV2

Franc Llorens Institute of Neuropathology; IDIBELL-University Hospital Bellvitge; University of Barcelona; Hospitalet de Llobregat; Barcelona, Spain; CIBERNED (Network Center for Biomedical Research of Neurodegenerative Diseases); Institute Carlos III; Ministry of Health; Madrid, Spain; Department of Neurology; Clinical Dementia Center and DZNE; University Medical School; Georg-August University; Göttingen, Germany
,
Belén Ansoleaga Institute of Neuropathology; IDIBELL-University Hospital Bellvitge; University of Barcelona; Hospitalet de Llobregat; Barcelona, Spain; CIBERNED (Network Center for Biomedical Research of Neurodegenerative Diseases); Institute Carlos III; Ministry of Health; Madrid, Spain
,
Paula Garcia-Esparcia Institute of Neuropathology; IDIBELL-University Hospital Bellvitge; University of Barcelona; Hospitalet de Llobregat; Barcelona, Spain; CIBERNED (Network Center for Biomedical Research of Neurodegenerative Diseases); Institute Carlos III; Ministry of Health; Madrid, Spain
,
Saima Zafar Department of Neurology; Clinical Dementia Center and DZNE; University Medical School; Georg-August University; Göttingen, Germany
,
Oriol Grau-Rivera CJD-Unit and Alzheimer disease and Other Cognitive Disorders Unit; Department of Neurology; Hospital Clínic; Barcelona, Spain
,
Irene López-González Institute of Neuropathology; IDIBELL-University Hospital Bellvitge; University of Barcelona; Hospitalet de Llobregat; Barcelona, Spain; CIBERNED (Network Center for Biomedical Research of Neurodegenerative Diseases); Institute Carlos III; Ministry of Health; Madrid, Spain
,
Rosi Blanco Institute of Neuropathology; IDIBELL-University Hospital Bellvitge; University of Barcelona; Hospitalet de Llobregat; Barcelona, Spain; CIBERNED (Network Center for Biomedical Research of Neurodegenerative Diseases); Institute Carlos III; Ministry of Health; Madrid, Spain
,
Margarita Carmona Institute of Neuropathology; IDIBELL-University Hospital Bellvitge; University of Barcelona; Hospitalet de Llobregat; Barcelona, Spain; CIBERNED (Network Center for Biomedical Research of Neurodegenerative Diseases); Institute Carlos III; Ministry of Health; Madrid, Spain
,
Jordi Yagüe CJD-Unit and Alzheimer disease and Other Cognitive Disorders Unit; Department of Neurology; Hospital Clínic; Barcelona, Spain; Department of Immunology; Hospital Clinic; Barcelona, Spain
,
Carlos Nos General Subdirectorate of Surveillance and Response to Emergencies in Public Health; Department of Public Health in Catalonia; Barcelona, Spain
,
José Antonio del Río CIBERNED (Network Center for Biomedical Research of Neurodegenerative Diseases); Institute Carlos III; Ministry of Health; Madrid, Spain; Molecular and Cellular Neurobiotechnology; Catalonian Institute for Bioengineering (IBEC); Parc Científic de Barcelona; Barcelona, Spain; Department of Cell Biology; University of Barcelona; Barcelona, Spain
,
Ellen Gelpí Neurological Tissue Bank of the Biobanc-Hospital; Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS); Barcelona, Spain
,
Inga Zerr Department of Neurology; Clinical Dementia Center and DZNE; University Medical School; Georg-August University; Göttingen, Germany
&
Isidre Ferrer Institute of Neuropathology; IDIBELL-University Hospital Bellvitge; University of Barcelona; Hospitalet de Llobregat; Barcelona, Spain; CIBERNED (Network Center for Biomedical Research of Neurodegenerative Diseases); Institute Carlos III; Ministry of Health; Madrid, SpainCorrespondence[email protected]
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Pages 383-393 | Received 14 Jun 2013, Accepted 07 Sep 2013, Published online: 18 Sep 2013

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Katrin Thüne, Matthias Schmitz, Anna Villar-Piqué, Hermann Clemens Altmeppen, Markus Schlomm, Saima Zafar, Markus Glatzel, Franc Llorens & Inga Zerr. (2019) The cellular prion protein and its derived fragments in human prion diseases and their role as potential biomarkers. Expert Review of Molecular Diagnostics 19:11, pages 1007-1018.
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Filippo Baldacci, Simone Lista, Giovanni Palermo, Filippo Sean Giorgi, Andrea Vergallo & Harald Hampel. (2019) The neuroinflammatory biomarker YKL-40 for neurodegenerative diseases: advances in development. Expert Review of Proteomics 16:7, pages 593-600.
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Iris J. Broce, Eduardo Caverzasi, Simone Sacco, Ryan Michael Nillo, Matteo Paoletti, Rahul S. Desikan, Michael Geschwind & Leo P. Sugrue. (2023) PRNP expression predicts imaging findings in sporadic Creutzfeldt‐Jakob disease . Annals of Clinical and Translational Neurology 10:4, pages 536-552.
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Martina Tarozzi, Simone Baiardi, Claudia Sala, Anna Bartoletti-Stella, Piero Parchi, Sabina Capellari & Gastone Castellani. (2022) Genomic, transcriptomic and RNA editing analysis of human MM1 and VV2 sporadic Creutzfeldt-Jakob disease. Acta Neuropathologica Communications 10:1.
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A. Matamoros-Angles, A. Hervera, J. Soriano, E. Martí, P. Carulla, F. Llorens, M. Nuvolone, A. Aguzzi, I. Ferrer, A. Gruart, J. M. Delgado-García & J. A. Del Río. (2022) Analysis of co-isogenic prion protein deficient mice reveals behavioral deficits, learning impairment, and enhanced hippocampal excitability. BMC Biology 20:1.
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Izabella Grimaldi, Felipe Saceanu Leser, José Marcos Janeiro, Bárbara Gomes da Rosa, Ana Clara Campanelli, Luciana Romão & Flavia Regina Souza Lima. (2022) The multiple functions of PrPC in physiological, cancer, and neurodegenerative contexts. Journal of Molecular Medicine 100:10, pages 1405-1425.
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Laia Lidón, Cristina Vergara, Isidro Ferrer, Félix Hernández, Jesús Ávila, Jose A. del Rio & Rosalina Gavín. (2020) Tau Protein as a New Regulator of Cellular Prion Protein Transcription. Molecular Neurobiology 57:10, pages 4170-4186.
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