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Review

HLA‑B27 misfolding and spondyloarthropathies

Robert A. Colbert Division of Rheumatology, Cincinnati Children's Hospital Medical Center Correspondence[email protected]
,
Monica L. DeLay Division of Rheumatology, Cincinnati Children's Hospital Medical Center
,
Gerlinde Layh-Schmitt Division of Rheumatology, Cincinnati Children's Hospital Medical Center
&
Dawn P. Sowders Division of Rheumatology, Cincinnati Children's Hospital Medical Center
Pages 15-26 | Received 03 Feb 2009, Accepted 03 Feb 2009, Published online: 01 Jan 2009

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Alireza Rezaiemanesh, Mahdi Mahmoudi, Ali Akbar Amirzargar, Mahdi Vojdanian, Ahmad Reza Jamshidi & Mohammad Hossein Nicknam. (2017) Ankylosing spondylitis M-CSF-derived macrophages are undergoing unfolded protein response (UPR) and express higher levels of interleukin-23. Modern Rheumatology 27:5, pages 862-867.
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Mohamed A Saad, Amal B Abdul-Sattar, Ibrahim T Abdelal & Ahmed Baraka. (2023) Shedding Light on the Role of ERAP1 in Axial Spondyloarthritis. Cureus.
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Jichong Zhu, Weiming Tan, Xinli Zhan, Qing Lu, Tuo Liang, JieJiang, Hao Li, Chenxing Zhou, Shaofeng Wu, Tianyou Chen, Yuanlin Yao, Shian Liao, Chaojie Yu, Liyi Chen & Chong Liu. (2023) Development and validation of a machine learning-based nomogram for predicting HLA-B27 expression. BMC Immunology 24:1.
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Kristina Lejon, Urban Hellman, Lan Do, Anjani Kumar & Helena Forsblad‐d’Elia. (2022) Increased proportions of inflammatory T cells and their correlations with cytokines and clinical parameters in patients with ankylosing spondylitis from northern Sweden. Scandinavian Journal of Immunology 96:3.
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Sanjukta Majumder, Shivika Guleria & Amita Aggarwal. (2022) IL-36γ in enthesitis-related juvenile idiopathic arthritis and its association with disease activity. Clinical and Experimental Immunology 208:2, pages 212-219.
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Amit Kumar Thakur & Manni Luthra-Guptasarma. (2022) Differences in Cellular Clearing Mechanisms of Aggregates of Two Subtypes of HLA-B27. Frontiers in Immunology 12.
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Mazdak Ganjalikhani Hakemi. 2022. Ankylosing Spondylitis - Axial Spondyloarthritis. Ankylosing Spondylitis - Axial Spondyloarthritis 85 110 .
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Fabio Massimo Perrotta, Rik Lories & Ennio Lubrano. (2021) To move or not to move: the paradoxical effect of physical exercise in axial spondyloarthritis. RMD Open 7:1, pages e001480.
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Valentina Tedeschi, Giorgia Paldino, Fabiana Paladini, Benedetta Mattorre, Loretta Tuosto, Rosa Sorrentino & Maria Teresa Fiorillo. (2020) The Impact of the ‘Mis-Peptidome’ on HLA Class I-Mediated Diseases: Contribution of ERAP1 and ERAP2 and Effects on the Immune Response. International Journal of Molecular Sciences 21:24, pages 9608.
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Wei Zhu, Xuxia He, Kaiyuan Cheng, Linjie Zhang, Di Chen, Xiao Wang, Guixing Qiu, Xu Cao & Xisheng Weng. (2019) Ankylosing spondylitis: etiology, pathogenesis, and treatments. Bone Research 7:1.
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Elena Generali & Carlo Selmi. 2019. Mosaic of Autoimmunity. Mosaic of Autoimmunity 217 227 .
Elena Generali, Tanima Bose, Carlo Selmi, J. Willem Voncken & Jan G.M.C. Damoiseaux. (2018) Nature versus nurture in the spectrum of rheumatic diseases: Classification of spondyloarthritis as autoimmune or autoinflammatory. Autoimmunity Reviews 17:9, pages 935-941.
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Bin Chen, Jia Li, Chongru He, Dahe Li, Wenwen Tong, Yuming Zou & Weidong Xu. (2017) Role of HLA-B27 in the pathogenesis of ankylosing spondylitis (Review). Molecular Medicine Reports.
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Fahmi AlDhaheri, Talal Almteri, Naji Dwid, Ahd Majdali, Nahed Janoudi & Hani Almoallim. (2017) Rituximab Can Induce Remission in a Patient with Ankylosing Spondylitis Who Failed Anti-TNF-α Agent. American Journal of Case Reports 18, pages 143-147.
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Erik Letko. 2017. Uveitis. Uveitis 171 175 .
Aurelian Anghelescu, Liliana Valentina Onose, Cristina Popescu, Ioana Andone, Cristina Octaviana Daia, Anca Magdalena Magdoiu, Aura Spanu & Gelu Onose. (2016) Evolution of traumatic spinal cord injury in patients with ankylosing spondylitis, in a Romanian rehabilitation clinic. Spinal Cord Series and Cases 2:1.
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Abhijeet Danve & James O'Dell. (2015) The ongoing quest for biomarkers in Ankylosing Spondylitis. International Journal of Rheumatic Diseases 18:8, pages 826-834.
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Anuj Shukla, Priyanka Gaur & Amita Aggarwal. (2015) Tenascin-C Levels, A Toll-like Receptor 4 Ligand, in Enthesitis-related Arthritis Category of Juvenile Idiopathic Arthritis: A Cross-sectional and Longitudinal Study. The Journal of Rheumatology 42:5, pages 891-896.
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César Pacheco-Tena & Susana Aideé González-Chávez. (2015) The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases. Journal of Immunology Research 2015, pages 1-23.
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W. M. Howell. (2014) HLA and disease: guilt by association. International Journal of Immunogenetics 41:1, pages 1-12.
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Amribet Meryem, Bourhim Noureddine, Mkinsi Slaoui Ouafaa, Belhouari Abderrahmane, Naya Abdellah, Fadli Mohamed & Bennani Siham. (2013) HLA-B27 Subtypes Distribution among Moroccan Patients with Ankylosing Spondylitis. American Journal of Medical and Biological Research 1:1, pages 28-32.
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José Francisco Zambrano-Zaragoza, Juan Manuel Agraz-Cibrian, Christian González-Reyes, Ma. de Jesús Durán-Avelar & Norberto Vibanco-Pérez. (2013) Ankylosing Spondylitis: From Cells to Genes. International Journal of Inflammation 2013, pages 1-16.
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David Yu, Rik Lories & Robert D. Inman. 2013. Kelley's Textbook of Rheumatology. Kelley's Textbook of Rheumatology 1193 1201 .
Barbara Neerinckx & Rik J Lories. (2012) Emerging concepts in ankylosing spondylitis. International Journal of Clinical Rheumatology 7:5, pages 515-526.
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Anthoula Chatzikyriakidou, Paraskevi V. Voulgari & Alexandros A. Drosos. (2011) What is the role of HLA-B27 in spondyloarthropathies?. Autoimmunity Reviews 10:8, pages 464-468.
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Rubén Burgos-Vargas & Janitzia Vázquez-Mellado. 2011. Textbook of Pediatric Rheumatology. Textbook of Pediatric Rheumatology 591 599 .
Lai-Shan Tam, Jieruo Gu & David Yu. (2010) Pathogenesis of ankylosing spondylitis. Nature Reviews Rheumatology 6:7, pages 399-405.
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Stefania Lenna, Danyelle M. Townsend, Filemon K. Tan, Bagrat Kapanadze, Malgorzata Markiewicz, Maria Trojanowska & Raffaella Scorza. (2010) HLA-B35 Upregulates Endothelin-1 and Downregulates Endothelial Nitric Oxide Synthase via Endoplasmic Reticulum Stress Response in Endothelial Cells. The Journal of Immunology 184:9, pages 4654-4661.
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N. J. Sheehan. (2010) HLA-B27: what's new?. Rheumatology 49:4, pages 621-631.
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