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Metal binding sheds light on mechanisms of amyloid assembly

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Pages 1-4 | Received 07 Sep 2008, Accepted 28 Jan 2009, Published online: 01 Jan 2009

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Alexandra I Mot, Anthony G Wedd, Layla Sinclair, David R Brown, Steven J Collins & Marcus W Brazier. (2011) Metal attenuating therapies in neurodegenerative disease. Expert Review of Neurotherapeutics 11:12, pages 1717-1745.
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Aneika C. Leney, Clare L. Pashley, Charlotte A. Scarff, Sheena E. Radford & Alison E. Ashcroft. (2014) Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry. Mol. BioSyst. 10:3, pages 412-420.
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Timo Eichner & Sheena E. Radford. (2011) Understanding the complex mechanisms of ?2-microglobulin amyloid assembly. FEBS Journal 278:20, pages 3868-3883.
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Lila M. Gierasch. (2011) How One Bad Protein Spoils the Barrel: Structural Details of ?2-Microglobulin Amyloidogenicity. Molecular Cell 41:2, pages 129-131.
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Timo Eichner, Arnout P. Kalverda, Gary S. Thompson, Steve W. Homans & Sheena E. Radford. (2011) Conformational Conversion during Amyloid Formation at Atomic Resolution. Molecular Cell 41:2, pages 161-172.
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Rapole Srikanth, Vanessa Leah Mendoza, Juma D. Bridgewater, Guanshi Zhang & Richard W. Vachet. (2009) Copper Binding to β-2-Microglobulin and Its Pre-Amyloid Oligomers. Biochemistry 48:41, pages 9871-9881.
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Dorottya V. Blaho & Andrew D. Miranker. (2009) Delineating the Conformational Elements Responsible for Cu 2+ -Induced Oligomerization of β-2 Microglobulin . Biochemistry 48:28, pages 6610-6617.
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