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Review

Prion propagation by Hsp40 molecular chaperones

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Pages 59-64 | Received 20 Mar 2009, Accepted 20 May 2009, Published online: 01 Apr 2009

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You-Lin Xue, Hao Wang, Michael Riedy, Brittany-Lee Roberts, Yuna Sun, Yong-Bo Song, Gary W. Jones, Daniel C. Masison & Youtao Song. (2018) Molecular dynamics simulations of Hsp40 J-domain mutants identifies disruption of the critical HPD-motif as the key factor for impaired curing in vivo of the yeast prion [URE3]. Journal of Biomolecular Structure and Dynamics 36:7, pages 1764-1775.
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William M. Holmes, Courtney L. Klaips & Tricia R. Serio. (2014) Defining the limits: Protein aggregation and toxicity in vivo. Critical Reviews in Biochemistry and Molecular Biology 49:4, pages 294-303.
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Ben Shabat Moti, Eliya Oz, Azrilin Olga, Gross Bella, Sela Shifra & Palzur Eilam. (2021) New Cortical Neurodegenerative Pathways in the Hypertensive Rat Brain. Cerebral Cortex 31:12, pages 5487-5496.
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Melanie Y. Pullen, Conrad C. Weihl & Heather L. True. (2020) Client processing is altered by novel myopathy-causing mutations in the HSP40 J domain. PLOS ONE 15:6, pages e0234207.
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Arun Upadhyay. (2019) Structure of proteins: Evolution with unsolved mysteries. Progress in Biophysics and Molecular Biology 149, pages 160-172.
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Zheng-Gang Han, Ji-Wen Zhang, Xiao-Fang Jiang & Jiang-Ke Yang. (2019) Gene dosage and coexpression with endoplasmic reticulum secretion-associated factors improved the secretory expression of α-galactosidase. Protein Expression and Purification 153, pages 83-91.
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Tatiana A. Chernova, Keith D. Wilkinson & Yury O. Chernoff. (2017) Prions, Chaperones, and Proteostasis in Yeast. Cold Spring Harbor Perspectives in Biology 9:2, pages a023663.
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Lydia M. Young, Ling-Hsien Tu, Daniel P. Raleigh, Alison E. Ashcroft & Sheena E. Radford. (2017) Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers. Chemical Science 8:7, pages 5030-5040.
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Emily R Hildebrandt, Michael Cheng, Peng Zhao, June H Kim, Lance Wells & Walter K Schmidt. (2016) A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes. eLife 5.
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Behrooz Moosavi, Bibimaryam Mousavi & Guang-Fu Yang. (2016) Actin, Membrane Trafficking and the Control of Prion Induction, Propagation and Transmission in Yeast. Traffic 17:1, pages 5-20.
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Gregory A Cary, Dani B N Vinh, Patrick May, Rolf Kuestner & Aimée M Dudley. (2015) Proteomic Analysis of Dhh1 Complexes Reveals a Role for Hsp40 Chaperone Ydj1 in Yeast P-Body Assembly. G3 Genes|Genomes|Genetics 5:11, pages 2497-2511.
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Navinder Kumar, Deepika Gaur, Arpit Gupta, Anuradhika Puri & Deepak Sharma. (2015) Hsp90-Associated Immunophilin Homolog Cpr7 Is Required for the Mitotic Stability of [URE3] Prion in Saccharomyces cerevisiae. PLOS Genetics 11:10, pages e1005567.
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Robert W. Walters, Denise Muhlrad, Jennifer Garcia & Roy Parker. (2015) Differential effects of Ydj1 and Sis1 on Hsp70-mediated clearance of stress granules in Saccharomyces cerevisiae . RNA 21:9, pages 1660-1671.
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David Z. Mokry, Josielle Abrahão & Carlos H.I. Ramos. (2015) Disaggregases, molecular chaperones that resolubilize protein aggregates. Anais da Academia Brasileira de Ciências 87:2 suppl, pages 1273-1292.
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Michael Reidy, Ruchika Sharma, Shankar Shastry, Brittany-Lee Roberts, Ivan Albino-Flores, Sue Wickner & Daniel C. Masison. (2014) Hsp40s Specify Functions of Hsp104 and Hsp90 Protein Chaperone Machines. PLoS Genetics 10:10, pages e1004720.
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Ayala Shiber & Tommer Ravid. (2014) Chaperoning Proteins for Destruction: Diverse Roles of Hsp70 Chaperones and their Co-Chaperones in Targeting Misfolded Proteins to the Proteasome. Biomolecules 4:3, pages 704-724.
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Panchanan Maiti, Jayeeta Manna, Shobi Veleri & Sally Frautschy. (2014) Molecular Chaperone Dysfunction in Neurodegenerative Diseases and Effects of Curcumin. BioMed Research International 2014, pages 1-14.
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Marion Delenclos & Pamela J. McLean. 2013. Inhibitors of Molecular Chaperones as Therapeutic Agents. Inhibitors of Molecular Chaperones as Therapeutic Agents 392 413 .
Kuljit Singh, Aliabbas A. Saleh, Ankan K. Bhadra & Ipsita Roy. (2013) Hsp104 as a key modulator of prion-mediated oxidative stress in Saccharomyces cerevisiae . Biochemical Journal 454:2, pages 217-225.
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Sae-Hun Park, Yury Kukushkin, Rajat Gupta, Taotao Chen, Ayano Konagai, Mark S. Hipp, Manajit Hayer-Hartl & F. Ulrich Hartl. (2013) PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone. Cell 154:1, pages 134-145.
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David L. Lancaster, C. Melissa Dobson & Richard A. Rachubinski. (2013) Chaperone Proteins Select and Maintain [PIN+] Prion Conformations in Saccharomyces cerevisiae. Journal of Biological Chemistry 288:2, pages 1266-1276.
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Gladis M. Walter, Matthew C. Smith, Susanne Wisén, Venkatesha Basrur, Kojo S.J. Elenitoba-Johnson, Martin L. Duennwald, Anuj Kumar & Jason E. Gestwicki. (2011) Ordered Assembly of Heat Shock Proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on Expanded Polyglutamine Fragments Revealed by Chemical Probes. Journal of Biological Chemistry 286:47, pages 40486-40493.
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James F. Graham, Sonya Agarwal, Dominic Kurian, Louise Kirby, Teresa J.T. Pinheiro & Andrew C. Gill. (2010) Low Density Subcellular Fractions Enhance Disease-specific Prion Protein Misfolding. Journal of Biological Chemistry 285:13, pages 9868-9880.
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