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Research Paper

Context dependent neuroprotective properties of prion protein (PrP)

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Pages 240-249 | Received 27 Jun 2009, Accepted 16 Sep 2009, Published online: 01 Oct 2009

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Read on this site (3)

Franc Llorens & José Antonio del Río. (2012) Unraveling the neuroprotective mechanisms of PrPC in excitotoxicity. Prion 6:3, pages 245-251.
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Michael M. J. Fischer. (2011) In the Science Zone Ii: The Fore, Papua New Guinea, and the Fight for Representation. East Asian Science, Technology and Society: An International Journal 5:1, pages 87-102.
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Keith M. Gunapala, Daniel Chang, Cynthia T. Hsu, Kebreten Manaye, Ryan M. Drenan, Robert C. Switzer & Andrew D. Steele. (2010) Striatal pathology underlies prion infection-mediated hyperactivity in mice. Prion 4:4, pages 302-315.
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Articles from other publishers (26)

Elisabetta Mantuano, Carlotta Zampieri, Pardis Azmoon, Cory B. Gunner, Kyle R. Heye & Steven L. Gonias. (2023) An LRP1-binding motif in cellular prion protein replicates cell-signaling activities of the full-length protein. JCI Insight 8:15.
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Sungtae Yoon, Gyeongyun Go, Yeomin Yoon, Jiho Lim, Gaeun Lee & Sanghun Lee. (2021) Harnessing the Physiological Functions of Cellular Prion Protein in the Kidneys: Applications for Treating Renal Diseases. Biomolecules 11:6, pages 784.
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Øyvind Salvesen, Jörg Tatzelt & Michael A. Tranulis. (2019) The prion protein in neuroimmune crosstalk. Neurochemistry International 130, pages 104335.
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Cheng Zhu, Matthew V. BeckJack D. Griffith, Mohanish DeshmukhNikolay V. Dokholyan. (2018) Large SOD1 aggregates, unlike trimeric SOD1, do not impact cell viability in a model of amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences 115:18, pages 4661-4665.
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Laura Urrea, Miriam Segura-Feliu, Masami Masuda-Suzukake, Arnau Hervera, Lucas Pedraz, José Manuel García Aznar, Miquel Vila, Josep Samitier, Eduard Torrents, Isidro Ferrer, Rosalina Gavín, Masato Hagesawa & José Antonio del Río. (2017) Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons. Molecular Neurobiology 55:3, pages 1847-1860.
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Joel C. Watts, Matthew E. C. Bourkas & Hamza Arshad. (2017) The function of the cellular prion protein in health and disease. Acta Neuropathologica 135:2, pages 159-178.
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Ø. Salvesen, M. R. Reiten, A. Espenes, M. K. Bakkebø, M. A. Tranulis & C. Ersdal. (2017) LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface. Journal of Neuroinflammation 14:1.
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Marie-Angela Wulf, Assunta Senatore & Adriano Aguzzi. (2017) The biological function of the cellular prion protein: an update. BMC Biology 15:1.
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Rafael Linden. (2017) The Biological Function of the Prion Protein: A Cell Surface Scaffold of Signaling Modules. Frontiers in Molecular Neuroscience 10.
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Lech Kaczmarczyk, Ylva Mende, Branko Zevnik & Walker S. Jackson. (2016) Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9. PLOS ONE 11:4, pages e0154604.
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Ajai K. Tripathi & Neena Singh. (2016) Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease. Journal of Alzheimer's Disease 51:1, pages 107-121.
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Edvin Ingberg, Hua Dock, Elvar Theodorsson, Annette Theodorsson & Jakob O. Ström. (2016) Method parameters’ impact on mortality and variability in mouse stroke experiments: a meta-analysis. Scientific Reports 6:1.
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Bo Zhang, Daniel Cowden, Fan Zhang, Jue Yuan, Sandra Siedlak, Mai Abouelsaad, Liang Zeng, Xuefeng Zhou, John O'Toole, Alvin S. Das, Diane Kofskey, Miriam Warren, Zehua Bian, Yuqi Cui, Tao Tan, Adam Kresak, Robert E. Wyza, Robert B. Petersen, Gong-Xian Wang, Qingzhong Kong, Xinglong Wang, John Sedor, Xiongwei Zhu, Hua Zhu & Wen-Quan Zou. (2015) Prion Protein Protects against Renal Ischemia/Reperfusion Injury. PLOS ONE 10:9, pages e0136923.
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Nunzio Iraci, Claudia Stincardini, Maria Letizia Barreca & Emiliano Biasini. (2015) Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases. Virus Research 207, pages 62-68.
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C. Vergara, L. Ordóñez-Gutiérrez, F. Wandosell, I. Ferrer, J. A. del Río & R. Gavín. (2014) Role of PrPC Expression in Tau Protein Levels and Phosphorylation in Alzheimer’s Disease Evolution. Molecular Neurobiology 51:3, pages 1206-1220.
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Sylvaine Huc-Brandt, Nelson Hieu, Thibaut Imberdis, Nicolas Cubedo, Michelle Silhol, Patricia L. A. Leighton, Thomas Domaschke, W. Ted Allison, Véronique Perrier & Mireille Rossel. (2014) Zebrafish Prion Protein PrP2 Controls Collective Migration Process during Lateral Line Sensory System Development. PLoS ONE 9:12, pages e113331.
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Stefanie A. G. Black, Peter K. Stys, Gerald W. Zamponi & Shigeki Tsutsui. (2014) Cellular prion protein and NMDA receptor modulation: protecting against excitotoxicity. Frontiers in Cell and Developmental Biology 2.
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Rafael M. Mariante, Alberto Nóbrega, Rodrigo A.P. Martins, Rômulo B. Areal, Maria Bellio & Rafael Linden. (2012) Neuroimmunoendocrine Regulation of the Prion Protein in Neutrophils. Journal of Biological Chemistry 287:42, pages 35506-35515.
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Patricia Carulla, Ana Bribián, Alejandra Rangel, Rosalina Gavín, Isidro Ferrer, Carme Caelles, José Antonio del Río & Franc Llorens. (2011) Neuroprotective role of PrP C against kainate-induced epileptic seizures and cell death depends on the modulation of JNK3 activation by GluR6/7–PSD-95 binding . Molecular Biology of the Cell 22:17, pages 3041-3054.
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Benoît Vanderperre, Antanas B. Staskevicius, Guillaume Tremblay, Marie McCoy, Megan A. O'Neill, Neil R. Cashman & Xavier Roucou. (2011) An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein . The FASEB Journal 25:7, pages 2373-2386.
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Kelly A Barton & Byron Caughey. (2011) Is PrP the road to ruin?. The EMBO Journal 30:10, pages 1882-1884.
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Elodie Angot, Jennifer A Steiner, Christian Hansen, Jia-Yi Li & Patrik Brundin. (2010) Are synucleinopathies prion-like disorders?. The Lancet Neurology 9:11, pages 1128-1138.
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C Li, W Xin & M-S Sy. (2010) Binding of pro-prion to filamin A: by design or an unfortunate blunder. Oncogene 29:39, pages 5329-5345.
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Man-Sun Sy, Chaoyang Li, Shuiliang Yu & Wei Xin. (2010) The fatal attraction between pro-prion and filamin A: prion as a marker in human cancers. Biomarkers in Medicine 4:3, pages 453-464.
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David A. Gimbel, Haakon B. Nygaard, Erin E. Coffey, Erik C. Gunther, Juha Laurén, Zachary A. Gimbel & Stephen M. Strittmatter. (2010) Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein. The Journal of Neuroscience 30:18, pages 6367-6374.
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Mimi Cushman, Brian S. Johnson, Oliver D. King, Aaron D. Gitler & James Shorter. (2010) Prion-like disorders: blurring the divide between transmissibility and infectivity. Journal of Cell Science 123:8, pages 1191-1201.
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