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xRRM

A new class of RRM found in the telomerase La family protein p65

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Pages 353-359 | Received 14 Dec 2012, Accepted 14 Jan 2013, Published online: 17 Jan 2013

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Ritwika Basu, Catherine D. Eichhorn, Ryan Cheng, Robert D. Peterson & Juli Feigon. (2021) Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins. RNA Biology 18:8, pages 1181-1192.
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Sandy Mattijssen, Guennadi Kozlov, Bruno D. Fonseca, Kalle Gehring & Richard J. Maraia. (2021) LARP1 and LARP4: up close with PABP for mRNA 3’ poly(A) protection and stabilization. RNA Biology 18:2, pages 259-274.
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Daniele Hasler, Gunter Meister & Utz Fischer. (2021) Stabilize and connect: the role of LARP7 in nuclear non-coding RNA metabolism. RNA Biology 18:2, pages 290-303.
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Mark A. Bayfield, Jyotsna Vinayak, Kyra Kerkhofs & Farnaz Mansouri-Noori. (2021) La proteins couple use of sequence-specific and non-specific binding modes to engage RNA substrates. RNA Biology 18:2, pages 168-177.
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Articles from other publishers (25)

Jennifer Porat, Viktor A Slat, Stephen D Rader & Mark A Bayfield. (2023) The fission yeast methyl phosphate capping enzyme Bmc1 guides 2′-O-methylation of the U6 snRNA. Nucleic Acids Research.
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Yaqiang Wang, Yao He, Yanjiao Wang, Yuan Yang, Mahavir Singh, Catherine D. Eichhorn, Xinyi Cheng, Yi Xiao Jiang, Z. Hong Zhou & Juli Feigon. (2023) Structure of LARP7 Protein p65–telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR. Journal of Molecular Biology 435:11, pages 168044.
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Jennifer Porat, Moaine El Baidouri, Jorg Grigull, Jean-Marc Deragon & Mark A. Bayfield. (2022) The methyl phosphate capping enzyme Bmc1/Bin3 is a stable component of the fission yeast telomerase holoenzyme. Nature Communications 13:1.
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Diego J. Páez-Moscoso, David V. Ho, Lili Pan, Katie Hildebrand, Kristi L. Jensen, Michaella J. Levy, Laurence Florens & Peter Baumann. (2022) A putative cap binding protein and the methyl phosphate capping enzyme Bin3/MePCE function in telomerase biogenesis. Nature Communications 13:1.
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Yaqiang Wang, Lukas Sušac & Juli Feigon. (2019) Structural Biology of Telomerase. Cold Spring Harbor Perspectives in Biology 11:12, pages a032383.
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M. Hosseini, F. Larti, Z. Fattahi, H. Najmabadi & K. Kahrizi. (2019) A splice-altering variant in LARP7 gene leads to exon exclusion. Gene Reports 15, pages 100375.
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Stefano A. Marrella, Kerene A. Brown, Farnaz Mansouri-Noori, Jennifer Porat, Derek J. Wilson & Mark A. Bayfield. (2019) An interdomain bridge influences RNA binding of the human La protein. Journal of Biological Chemistry 294:5, pages 1529-1540.
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Martyna Nowacka, Pietro Boccaletto, Elzbieta Jankowska, Tomasz Jarzynka, Janusz M Bujnicki & Stanislaw Dunin-Horkawicz. (2019) RRMdb—an evolutionary-oriented database of RNA recognition motif sequences. Database 2019.
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Carolina Lixa, Amanda Mujo, Mariana T. Q. de Magalhães, Fabio C. L. Almeida, Luis Mauricio T. R. Lima & Anderson S. Pinheiro. (2018) Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution. Journal of Biomolecular NMR 72:3-4, pages 179-192.
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Catherine D. Eichhorn, Yuan Yang, Lucas Repeta & Juli Feigon. (2018) Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. Proceedings of the National Academy of Sciences 115:28.
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Nathan H. Blewett & Richard J. Maraia. (2018) La involvement in tRNA and other RNA processing events including differences among yeast and other eukaryotes. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1861:4, pages 361-372.
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Amanda K. Mennie, Bettina A. Moser & Toru M. Nakamura. (2018) LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast. Nature Communications 9:1.
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Laura C. Collopy, Tracy L. Ware, Tomas Goncalves, Sunnvør í Kongsstovu, Qian Yang, Hanna Amelina, Corinne Pinder, Ala Alenazi, Vera Moiseeva, Siân R. Pearson, Christine A. Armstrong & Kazunori Tomita. (2018) LARP7 family proteins have conserved function in telomerase assembly. Nature Communications 9:1.
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Richard J. Maraia, Sandy Mattijssen, Isabel Cruz‐Gallardo & Maria R. Conte. (2017) The La and related RNA ‐binding proteins (LARPs): structures, functions, and evolving perspectives . WIREs RNA 8:6.
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John E. Brogie & David H. Price. (2017) Reconstitution of a functional 7SK snRNP. Nucleic Acids Research 45:11, pages 6864-6880.
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Kerene A. Brown, Samel Sharifi, Rawaa Hussain, Logan Donaldson, Mark A. Bayfield & Derek J. Wilson. (2016) Distinct Dynamic Modes Enable the Engagement of Dissimilar Ligands in a Promiscuous Atypical RNA Recognition Motif. Biochemistry 55:51, pages 7141-7150.
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Brody Holohan, Wanil Kim, Tsung-Po Lai, Hirotoshi Hoshiyama, Ning Zhang, Anas M. Alazami, Woodring E. Wright, M. Stephen Meyn, Fowzan S. Alkuraya & Jerry W. Shay. (2016) Impaired telomere maintenance in Alazami syndrome patients with LARP7 deficiency. BMC Genomics 17:S9.
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Catherine D. Eichhorn, Rahul Chug & Juli Feigon. (2016) hLARP7 C-terminal domain contains an xRRM that binds the 3′ hairpin of 7SK RNA. Nucleic Acids Research, pages gkw833.
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Galina A. Stepanyuk, Pedro Serrano, Eigen Peralta, Carol L. Farr, Herbert L. Axelrod, Michael Geralt, Debanu Das, Hsiu-Ju Chiu, Lukasz Jaroszewski, Ashley M. Deacon, Scott A. Lesley, Marc-André Elsliger, Adam Godzik, Ian A. Wilson, Kurt Wüthrich, Daniel R. Salomon & James R. Williamson. (2016) UHM–ULM interactions in the RBM39–U2AF65 splicing-factor complex. Acta Crystallographica Section D Structural Biology 72:4, pages 497-511.
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Sarah Loerch & Clara L. Kielkopf. (2015) Dividing and Conquering the Family of RNA Recognition Motifs: A Representative Case Based on hnRNP L. Journal of Molecular Biology 427:19, pages 2997-3000.
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Markus Blatter, Stanislaw Dunin-Horkawicz, Inna Grishina, Christophe Maris, Stephane Thore, Timm Maier, Albrecht Bindereif, Janusz M. Bujnicki & Frédéric H.-T. Allain. (2015) The Signature of the Five-Stranded vRRM Fold Defined by Functional, Structural and Computational Analysis of the hnRNP L Protein. Journal of Molecular Biology 427:19, pages 3001-3022.
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Emiko Uchikawa, Kundhavai S. Natchiar, Xiao Han, Florence Proux, Pierre Roblin, Elodie Zhang, Alexandre Durand, Bruno P. Klaholz & Anne-Catherine Dock-Bregeon. (2015) Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7. Nucleic Acids Research 43:6, pages 3373-3388.
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Tariq Afroz, Zuzana Cienikova, Antoine Cléry & Frédéric H.T. Allain. 2015. Structures of Large RNA Molecules and Their Complexes. Structures of Large RNA Molecules and Their Complexes 235 278 .
Fabiana Arieti, Caroline Gabus, Margherita Tambalo, Tiphaine Huet, Adam Round & Stéphane Thore. (2014) The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs. Nucleic Acids Research 42:10, pages 6742-6752.
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Xiao-qin Wu, Cheng Huang, Xu He, Yuan-yao Tian, De-xi Zhou, Yong He, Xin-hua Liu & Jun Li. (2013) Feedback regulation of telomerase reverse transcriptase: new insight into the evolving field of telomerase in cancer. Cellular Signalling 25:12, pages 2462-2468.
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