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Transcriptional stalling in B-lymphocytes

A mechanism for antibody diversification and maintenance of genomic integrity

Jianbo Sun Department of Microbiology and Immunology; College of Physicians and Surgeons; Columbia University; New York, NY USA

Gerson Rothschild Department of Microbiology and Immunology; College of Physicians and Surgeons; Columbia University; New York, NY USA

Evangelos Pefanis Department of Microbiology and Immunology; College of Physicians and Surgeons; Columbia University; New York, NY USA

Uttiya Basu Department of Microbiology and Immunology; College of Physicians and Surgeons; Columbia University; New York, NY USACorrespondence[email protected]

Pages 127-135 | Received 11 Mar 2013, Accepted 04 Apr 2013, Published online: 12 Apr 2013

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https://doi.org/10.4161/trns.24556

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Ravi K. Dinesh, Benjamin Barnhill, Anoj Ilanges, Lizhen Wu, Daniel A. Michelson, Filip Senigl, Jukka Alinikula, Jeffrey Shabanowitz, Donald F. Hunt & David G. Schatz. (2019) Transcription factor binding at Ig enhancers is linked to somatic hypermutation targeting. European Journal of Immunology 50:3, pages 380-395.
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Bart G Jones, Robert E Sealy, Rhiannon R Penkert, Sherri L Surman, Robert W Maul, Geoff Neale, Beisi Xu, Patricia J Gearhart & Julia L Hurwitz. (2019) Complex sex-biased antibody responses: estrogen receptors bind estrogen response elements centered within immunoglobulin heavy chain gene enhancers. International Immunology 31:3, pages 141-156.
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Evangelos Pefanis & Uttiya Basu. 2015. 257 308 .

Jaime Chao, Gerson Rothschild & Uttiya Basu. (2014) Ubiquitination Events That Regulate Recombination of Immunoglobulin Loci Gene Segments. Frontiers in Immunology 5.
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Filip Senigl, Yaakov Maman, Ravi K. Dinesh, Jukka Alinikula, Rashu B. Seth, Lubomira Pecnova, Arina D. Omer, Suhas S. P. Rao, David Weisz, Jean-Marie Buerstedde, Rafael Casellas, Erez Lieberman Aiden, Jiri Hejnar & David Schatz. (2019) Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation. SSRN Electronic Journal.
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Transcriptional stalling in B-lymphocytes

A mechanism for antibody diversification and maintenance of genomic integrity

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Transcriptional stalling in B-lymphocytes

A mechanism for antibody diversification and maintenance of genomic integrity

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