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Original Articles

Microbial Transglutaminase Production: Understanding the Mechanism

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Pages 205-222 | Published online: 15 Apr 2013

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Heba Sayed Mostafa. (2020) Microbial transglutaminase: An overview of recent applications in food and packaging. Biocatalysis and Biotransformation 38:3, pages 161-177.
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Karuna L. Sorde & Laxmi Ananthanarayan. (2019) Isolation, screening, and optimization of bacterial strains for novel transglutaminase production. Preparative Biochemistry & Biotechnology 49:1, pages 64-73.
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Articles from other publishers (36)

Xiaoqiang Yin, Shengqi Rao, Jingwen Zhou, Guocheng Du, Jian Chen & Song Liu. (2022) Improved Productivity of Streptomyces mobaraensis Transglutaminase by Regulating Zymogen Activation. Frontiers in Bioengineering and Biotechnology 10.
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Timothy J. Tse, Daniel J. Wiens, Farley Chicilo, Sarah K. Purdy & Martin J. T. Reaney. (2021) Value-Added Products from Ethanol Fermentation—A Review. Fermentation 7:4, pages 267.
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Syeda Warisul Fatima & Sunil K. Khare. (2021) Effect of key regulators in augmenting transcriptional expression of Transglutaminase in Streptomyces mobaraensis. Bioresource Technology 340, pages 125627.
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Lovaine Silva Duarte, Carla Roberta Matte, Paulo Roberto Dall Cortivo, José Eduardo Sacconi Nunes, Laisa Quadros Barsé, Cristiano Valim Bizarro & Marco Antônio Záchia Ayub. (2021) Expression of Bacillus amyloliquefaciens transglutaminase in recombinant E. coli under the control of a bicistronic plasmid system in DO-stat fed-batch bioreactor cultivations. Brazilian Journal of Microbiology 52:3, pages 1225-1233.
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Nan Zhang, Shan Zhang, Yongzhi He, Xin Chen, Yanfeng Zhang & Zhiyang Dong. (2020) Intein-mediated intracellular production of active microbial transglutaminase in Corynebacterium glutamicum. Enzyme and Microbial Technology 142, pages 109680.
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Elaine Berger Ceresino, Ramune Kuktaite, Mikael S. Hedenqvist, Hélia Harumi Sato & Eva Johansson. (2020) Processing conditions and transglutaminase sources to “drive” the wheat gluten dough quality. Innovative Food Science & Emerging Technologies 65, pages 102439.
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Aaron Lerner & Torsten Matthias. (2020) Processed Food Additive Microbial Transglutaminase and Its Cross-Linked Gliadin Complexes Are Potential Public Health Concerns in Celiac Disease. International Journal of Molecular Sciences 21:3, pages 1127.
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Lovaine Duarte, Carla Roberta Matte, Cristiano Valim Bizarro & Marco Antônio Záchia Ayub. (2020) Transglutaminases: part I—origins, sources, and biotechnological characteristics. World Journal of Microbiology and Biotechnology 36:1.
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Marjetka Gajšek, Urška Jančič, Katja Vasić, Željko Knez & Maja Leitgeb. (2019) Enhanced activity of immobilized transglutaminase for cleaner production technologies. Journal of Cleaner Production 240, pages 118218.
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Hilal Isleroglu, Izzet Turker, Banu Koc & Mehmet Tokatli. (2019) Microencapsulation of Microbial Transglutaminase by Ultrasonic Spray-Freeze Drying. Food and Bioprocess Technology 12:12, pages 2004-2017.
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Syeda Warisul Fatima, Rameshwar Tiwari & Sunil K. Khare. (2019) Utilization of agro-industrial waste for production of Transglutaminase from Streptomyces mobaraensis. Bioresource Technology 287, pages 121391.
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Erin J. Hopkins, Pierre Hucl, Martin G. Scanlon & Michael T. Nickerson. (2019) Effect of enzymatic crosslinking on the handling properties of dough as a function of NaCl levels for CWRS varieties, Pembina and Harvest. Journal of Texture Studies 50:4, pages 350-358.
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Elaine Berger Ceresino, Ramune Kuktaite, Hélia Harumi Sato, Mikael S. Hedenqvist & Eva Johansson. (2019) Impact of gluten separation process and transglutaminase source on gluten based dough properties. Food Hydrocolloids 87, pages 661-669.
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Lerner Aaron & Matthias Torsten. (2019) Microbial transglutaminase: A new potential player in celiac disease. Clinical Immunology 199, pages 37-43.
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Daniela Trono. 2019. Advances in Enzyme Technology. Advances in Enzyme Technology 349 387 .
Limin Wang, Bo Yu, Ruixuan Wang & Jianchun Xie. (2018) Biotechnological routes for transglutaminase production: Recent achievements, perspectives and limits. Trends in Food Science & Technology 81, pages 116-120.
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Hilal Isleroglu, Izzet Turker, Mehmet Tokatli & Banu Koc. (2018) Ultrasonic spray-freeze drying of partially purified microbial transglutaminase. Food and Bioproducts Processing 111, pages 153-164.
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Jean-Étienne R. L. Morlighem, Chen Huang, Qiwen Liao, Paula Braga Gomes, Carlos Daniel Pérez, Álvaro de Brandão Prieto-da-Silva, Simon Ming-Yuen Lee & Gandhi Rádis-Baptista. (2018) The Holo-Transcriptome of the Zoantharian Protopalythoa variabilis (Cnidaria: Anthozoa): A Plentiful Source of Enzymes for Potential Application in Green Chemistry, Industrial and Pharmaceutical Biotechnology. Marine Drugs 16:6, pages 207.
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Samuel K. Oteng-Pabi, Christopher M. Clouthier & Jeffrey W. Keillor. (2018) Design of a glutamine substrate tag enabling protein labelling mediated by Bacillus subtilis transglutaminase. PLOS ONE 13:5, pages e0197956.
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Brent M Dorr & Douglas E Fuerst. (2018) Enzymatic amidation for industrial applications. Current Opinion in Chemical Biology 43, pages 127-133.
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Elaine B. Ceresino, Ricardo R. de Melo, Ramune Kuktaite, Mikael S. Hedenqvist, Tiago D. Zucchi, Eva Johansson & Helia H. Sato. (2018) Transglutaminase from newly isolated Streptomyces sp. CBMAI 1617: Production optimization, characterization and evaluation in wheat protein and dough systems. Food Chemistry 241, pages 403-410.
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Gabe Javitt, Zohar Ben-Barak-Zelas, Moran Jerabek-Willemsen & Ayelet Fishman. (2017) Constitutive expression of active microbial transglutaminase in Escherichia coli and comparative characterization to a known variant. BMC Biotechnology 17:1.
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Wenjie Wan, Donglan He, Zhijun Xue & Zewen Zhang. (2017) Specific mutation of transglutaminase gene from Streptomyces hygroscopicus H197 and characterization of microbial transglutaminase. Journal of Biosciences 42:4, pages 537-546.
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Song Liu, Miao Wang, Guocheng Du & Jian Chen. (2016) Improving the active expression of transglutaminase in Streptomyces lividans by promoter engineering and codon optimization. BMC Biotechnology 16:1.
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Mathias Rickert, Pavel Strop, Victor Lui, Jody Melton-Witt, Santiago Esteban Farias, Davide Foletti, David Shelton, Jaume Pons & Arvind Rajpal. (2016) Production of soluble and active microbial transglutaminase in Escherichia coli for site-specific antibody drug conjugation . Protein Science 25:2, pages 442-455.
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Chengran Guan, Wenjing Cui, Xiaotian He, Xu Hu, Jun Xu, Guocheng Du, Jian Chen & Zhemin Zhou. (2015) Construction and development of a novel expression system of Streptomyces. Protein Expression and Purification 113, pages 17-22.
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Tanja Narancic, Reeta Davis, Jasmina Nikodinovic-Runic & Kevin E. O’ Connor. (2015) Recent developments in biocatalysis beyond the laboratory. Biotechnology Letters 37:5, pages 943-954.
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Marcela P. BagagliSahar JazaeriJayne E. BockKoushik SeetharamanHelia H. Sato. (2014) Effect of Transglutaminase, Citrate Buffer, and Temperature on a Soft Wheat Flour Dough System. Cereal Chemistry Journal 91:5, pages 460-465.
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Kun Du, Zhongmei Liu, Wenjing Cui, Li Zhou, Yi Liu, Guocheng Du, Jian Chen & Zhemin Zhou. (2014) pH-Dependent Activation of Streptomyces hygroscopicus Transglutaminase Mediated by Intein. Applied and Environmental Microbiology 80:2, pages 723-729.
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Natalie Rachel & Joelle Pelletier. (2013) Biotechnological Applications of Transglutaminases. Biomolecules 3:4, pages 870-888.
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Marcela Pavan Bagagli & Hélia Harumi Sato. (2013) Two-Staged Temperature and Agitation Strategy for the Production of Transglutaminase from a Streptomyces sp. Isolated from Brazilian Soils. Applied Biochemistry and Biotechnology 170:5, pages 1057-1065.
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Kangkang Chen, Song Liu, Dongxu Zhang, Miao Wang, Zhongping Shi, Guocheng Du & Jian Chen. (2013) Altered secretary efficiency of Streptomyces hygroscopicus transglutaminase in Escherichia coli by the pro-peptide modification. Process Biochemistry 48:5-6, pages 782-787.
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Shuhei Noda, Takaya Miyazaki, Tsutomu Tanaka, Ogino Chiaki & Akihiko Kondo. (2013) High-level production of mature active-form Streptomyces mobaraensis transglutaminase via pro-transglutaminase processing using Streptomyces lividans as a host. Biochemical Engineering Journal 74, pages 76-80.
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Rachel Chen. (2012) Bacterial expression systems for recombinant protein production: E. coli and beyond. Biotechnology Advances 30:5, pages 1102-1107.
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Song Liu, Dongxu Zhang, Miao Wang, Wenjing Cui, Kangkang Chen, Guocheng Du, Jian Chen & Zhemin Zhou. (2011) The order of expression is a key factor in the production of active transglutaminase in Escherichia coli by co-expression with its pro-peptide. Microbial Cell Factories 10:1.
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Song Liu, Dongxu Zhang, Miao Wang, Wenjing Cui, Kangkang Chen, Yi Liu, Guocheng Du, Jian Chen & Zhemin Zhou. (2011) The pro-region of Streptomyces hygroscopicus transglutaminase affects its secretion by Escherichia coli. FEMS Microbiology Letters 324:2, pages 98-105.
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