Low-sodium diet with adequate water intake improved the clinical efficacy in Ménière’s disease

Abstract

Background

Ménière’s disease (MD) is a common idiopathic inner ear disorder in otorhinolaryngology characterized by recurrent episodes of vertigo, fluctuating sensorineural hearing loss, tinnitus and ear fullness.

Objective

To study the effects of low-sodium diet with adequate water intake on the clinical efficacy in MD.

Methods

Fifty patients diagnosed with stage-3 unilateral MD were randomly divided into control group(n = 25) and experimental group(n = 25). The control group was given routine medication therapy, and the experimental group was restricted to an sodium intake of 1500 mg/d and a water intake of 35 ml/kg/d based in addition to the routine medication therapy. The two groups were assessed using pure tone audiometry, electrocochleography, Tinnitus Handicap Inventory (THI), and Dizziness Handicap Inventory (DHI).

Results

The pure tone audiometry and electrocochleography showed better improvements after treatment in the experimental group than the control group (p < 0.05). The THI improved values in the experimental group were significantly higher than the control group (p < 0.001). The DHI improved values in the experimental group were significantly higher than the control group (p = 0.004).

Conclusions and Significance

Low-sodium diet with adequate water intake improved the hearing and alleviated vertigo and tinnitus in MD patients.

Chinese Abstract

背景

梅尼埃病(MD)是耳鼻喉科常见的特发性内耳疾病, 其特征是反复发作的眩晕、波动性感音神经性听力损失、耳鸣和耳胀。

目的

研究低钠饮食加充足饮水对MD的临床疗效的影响。

方法

将 50 例诊断为 3 期单侧 MD的患者随机分为对照组(n = 25)和实验组(n = 25)。 对照组给予常规药物治疗；实验组除常规药物治疗外, 限制钠摄入量为1500mg/d, 水摄入量为35ml/kg/d。 两组的评估均采用纯音测听、耳蜗电图、耳鸣障碍量表 (THI) 和头晕障碍库存 (DHI)。

结果

纯音测听和耳蜗电图显示, 实验组治疗后表现出比对照组更好的改善(p < 0.05)。 实验组的THI 改善值显著高于对照组(p < 0.001)。 实验组的DHI 改善值显著高于对照组(p = 0.004)。

结论和意义

低钠饮食和充足的水摄入可以改善MD 患者的听力并缓解其眩晕和耳鸣。

Keywords:

• Ménière’s disease
• vertigo
• tinnitus
• low-sodium diet

Acknowledgements

None

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

None declared