Surface Interactions Studies of Novel Two-Dimensional Molybdenum Disulfide with Gram-Negative and Gram-Positive Bacteria

Abstract

The interaction between two-dimensional nanoflakes and bacteria in water-based physiological liquids is a hot topic that unveils new types of phenomena and is fundamental to bioscience applications. In this work, we extend Derjaguin, Landau, Verwey, and Overbeek theory (DLVO theory) that describes the properties of nano-objects in solutions, to the case of two-dimensional nanoflakes interacting with bacteria cell membranes, both for Gram-positive and Gram-negative bacteria. We have studied the role of the bacterial shape, membrane potential, and two-dimensional nanomaterials nature showing the interplay of these parameters in determining whether the interactions are attractive or repulsive and whether electrostatic or van der Waals forces are dominant. We calculated the interaction distances at equilibrium for different bacterial species and hydrophobic nanomaterials such as $Mo{S}_2$ in two environmentally friendly solvents, water and cyrene.

Keywords:

• Bacteria
• bacteria-surface interaction
• cyrene
• Derjaguin,-Landau-Verwey-Overbeek (DLVO) theory
• molybdenum disulfide
• $Mo{S}_2$
• two-dimensional nanomaterials
• zeta-potential

Acknowledgement

CA, MV, and MS acknowledge partial support for this work from MIUR (Italian Ministry for Research) under project PRIN “Predicting and controlling the fate of bio-molecules driven by extreme-ultraviolet radiation” (Prot. 20173B72NB).

Author contribution

CA, MS, and JA conceived the study and the theoretical model extension. JA carried on most of the calculations. MRDS, JA, and MS wrote the manuscript. All authors contributed to analyze the results of the article and approved the submitted version.

Competing interests

The authors declare that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.