High signal-intensity abnormalities in susceptibility-weighted imaging for primary intracerebral hemorrhage

Abstract

Purpose: To identify the regularity of signal evolution of intracerebral hemorrhage on susceptibility-weighted imaging (SWI) at different stages compared with T1-weighted imaging (T1WI) and T2-weighted imaging (T2WI).

Methods: We retrospectively evaluated a series of 365 patients who underwent T1WI, T2WI, and SWI examination simultaneously or sequentially in our hospital from January 2015 to May 2017. Two neuroradiologists assessed the images and discrepancies between their interpretations were resolved by consensus. Statistical analysis was performed using Chi-squared and Kappa tests.

Results: Of the 365 patients on SWI sequence, 94 were enrolled. SWI detected the cases at different stages; T1WI detected 89 cases and T2WI detected 91 cases. The signal intensity of intracerebral hemorrhage on SWI was significantly associated with T1WI imaging and T2WI (χ² = 4.651; p < 0.05; χ² = 26.396; p < 0.01, respectively), especially at the late subacute stage. There was moderate consistency between the signal intensity of intracerebral hemorrhage on T2WI and SWI (Kappa coefficient = 0.530).

Conclusion: Intracerebral hemorrhage has a varied appearance on SWI, and the evolution of signal of intracerebral hemorrhage on SWI sequence is influenced by T1WI and T2WI. Hematoma detection should be closely combined with clinical manifestation.

Keywords:

• Susceptibility-weighted imaging
• T1-weighted imaging
• T2-weighted imaging
• hyperintense
• intracerebral hemorrhage

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The study was supported by Young Teacher Foundation of Wuhan University, China (Grant No. 2042017kf0142) and Guidance Fund of Renmin Hospital of Wuhan University, China (Grant No. RMYD2018M19).