A convenient synthesis and crystal structure of disubstituted 1,2,3-triazoles having ether functionality

Abstract

A series of 27 ether-linked 1,4-disubstituted 1,2,3-triazoles (8a–8z₁) has been synthesized by 1,3 dipolar cycloaddition of 1-substituted-4-(prop-2-yn-1-yloxy)benzene (3a–3c) and aromatic azides (5a–5c, 7a–7f). The synthesized compounds were explicated by FTIR, ¹H NMR, ¹³C NMR and HRMS techniques. The structures of synthesized triazoles 8c (CCDC 1840219) and 8f (CCDC 1840220) were also confirmed by X-ray crystallography.

GRAPHICAL ABSTRACT

Keywords:

• Disubstituted 1,2,3-triazoles
• synthesis
• X-ray crystallography

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

Authors are highly thankful to DST, New Delhi for financial assistance sanctioned to GJU S&T, Hisar under PURSE program No. SR/PURSE Phase 2/40(G) and Central Instrumentation Laboratory, GJU S&T, Hisar.