Highly regioselective O-allylation of phenol derivatives using MMZ_Cu(I)Y catalyst

Abstract

A clean and effective method has been developed for the regioselective of O-allylation of phenol derivatives using a recyclable Cu(I)-exchanged multi-size porous material. Ease of preparation of catalyst through simple solid-state exchange and its compatibility in producing excellent amount of O-allylated products and a plausible mechanistic pathway for the regioselectivity are highlighted. This reported procedure is not requiring any external stabilizing ligand for Cu(I) species and further purification of products.

Graphical Abstract

Where X = H, p–Br, p–COCH_3, O–CHO, O–COCH_3, O–Cl, p–Cl, Ph, Py, heterobicyclic (3 examples).

Keywords:

• MMZ_Cu(I)Y
• O-allylation
• regioselectivity