Abstract
A series of compounds, in which a novel 6-(4-aminophenyl)pyrrolo[1,2-d][1,2,4]triazin-1(2H)-one derivatives were synthesized and tested for their antimicrobial and antifungal activities. Among all synthesized compounds, compound 7a showed remarkable antimicrobial activity with overall target micro-organisms and compounds 7g and 7l displayed significant inhibitory activity against Escherichia coli (Ec) and Scedosporium (Sc) respectively.
Graphical abstract
Acknowledgments
The author is grateful to the Dept of Chemistry, Don Bosco Institute of Technology, VTU for providing the necessary facilities to carry out this research work. We are grateful to the Department of Bio-Chemistry Don Bosco Institute of Technology for in vitro evaluation of antimicrobial and antifungal studies.