Palladium-catalyzed hydrogenations in dichloromethane

Abstract

Dichloromethane is shown to be a useful solvent in catalytic hydrogenation reactions of easily reduced functional groups (alkenes, alkynes, imines, and nitroarenes) using palladium on carbon as the catalyst under mild conditions (ambient pressure and temperature).

Graphical Abstract

Keywords:

• Catalytic hydrogenation
• dichloromethane
• ease of removal
• lack of flammability
• palladium on carbon

Supplementary Information

Full experimental detail, ¹H and ¹³C NMR spectra of products, and literature references for characterization data of known compounds can be found via the “Supplementary Information” section of this article’s webpage.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was supported in part by award 55503-ND7 from the Petroleum Research Fund, administered by the American Chemical Society.