Abstract
This review presents a vast body of literature on various synthetic methodology, biological, and fluorescence activities of pyrrolo[3,4‑c]coumarins as published during the last 20–30 years. Synthesized pyrrolo[3,4‑c]coumarins have been reported in the literature by the construction of either pyrrole, indole, or both rings via different synthetic methodology including metal-catalyzed reactions, and green reaction protocols starting from readily accessible substrates.
Graphical Abstract
![](/cms/asset/7fb980d5-3bde-4636-962c-4a2951b9cfc3/lsyc_a_2119413_uf0001_c.jpg)
This review presents the different synthetic approach of pyrrolo[3,4‑c]coumarins an isolamellarin-B via classical, metal-catalyzed and green reaction protocols starting from suitable precursors.
Acknowledgments
We thank Professor Gandhi Kumar Kar, Partha Pratim Mukhopadhyay and Dr. Pradipta Ghosh for their valuable suggestions.