Abstract
The present study describes an efficient and convenient one-pot multicomponent, microwave-assisted synthesis of polysubstituted-1H-imidazoles in good yields under mild reaction conditions. The procedure uses inexpensive, nontoxic, and reusable Amberlite IR120(H) as a catalyst. The new method exhibits a broad tolerance for diverse structural moieties, thereby demonstrating the robustness and applicability of the synthetic method. Further synthesized polysubstituted-1H-imidazoles exhibited moderate to good activity against bacterial strains under study.
Graphical Abstract
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Disclosure statement
The authors declare that there is no conflict of interest regarding the publication of this article.