Abstract
1. Challenges, strategies and new technologies in the field of biotransformation were presented and discussed at the fourth European Biotransformation Workshop which was held in collaboration with the joint ISSX/DMDG meeting on June 15, 2023 at the University of Hertfordshire in Hatfield, UK.
2. In this meeting report we summarise the presentations and discussions from this workshop.
3. The topics covered are listed below:
Unusual biotransformation reactions
Biotransformation Workflows in Discovery utilising various softwares for structure elucidation
Biotransformation software for the identification of peptide metabolites
Accelerator Mass Spectrometry (AMS) for endogenous and xenobiotic metabolite profiling
Metabolite profiling using quantitative Nuclear magnetic resonance (NMR) and liquid chromatography coupled to inductively coupled plasma-mass spectrometry (LC-ICP-MS)
Acknowledgements
The organizers would like to extend their gratitude to all presenters (Emre Isin, Axel Pähler, Dan Weston, Ismael Zamora, Elwin Verheij, Alexander David James and Petra Kern) and to all participants for fruitful discussions. We would like to acknowledge also the ISSX/DMDG organizing and technical team, in particular Stuart Hex and Chris Barron (AssociAction Enterprises). Without their support, this event would have not been possible.
Disclosure statement
No potential conflict of interest was reported by the author(s).