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ABSTRACT
A series of microwave irradiated IPN of Crg and GG have been synthesized and cross linking through hydrogen bonding was confirmed by FTIR spectroscopy. Thermal sensitivity at 48°C, degradation above 200°C is an emblem of uniqueness. We obtained micro rough surface morphology, hydrophilicity and muco-adhesion supporting S6 for targeted drug delivery. Honey comb like internal architecture will provide high mechanical strength. The sample S6 showed 72% drug release in 12 hours. Based on the results, it was concluded that the S6 can be used as target oriented controlled drug delivery devices enabling control over swelling and drug release.
GRAPHICAL ABSTRACT
Acknowledgments
The authors want to thank the University Grant Commission- Basic Scientific Research, Republic of India for financial support. A heartily gratitude is extended to the Central Instrumentation Facility, Birla Institute of Technology, Mesra, for technical assistance with sophisticated equipment. The authors also desire to appreciate Dr. A. K. Pattnaik, Dr. A Ghosh and Dr. H. K. Mahapatra for their valuable suggestions.