Six new lanthanide metal–organic frameworks as luminescent sensors for the detection of 1-N, TDGA, UA, and HA in urine

Abstract

The hydrothermal reaction of Ln(NO₃)₃·6H₂O with H₂tyia (H₂tyia = 5-(triazol-1-yl) isophthalic acid) afforded the lanthanide organic frameworks (Ln-MOFs), [Eu₂(tyia)₃(H₂O)₃]_n (1) and {[Ln₂(tyia)₃·(H₂O)₃]· 3H₂O}_n (Ln = Tb 2, Dy 3, Sm 4, Gd 5, and Nd 6). Compounds were characterized by routine methods: PXRD, elemental analysis, solid-state luminescence properties analysis, TGA, FT-IR, and single-crystal X-ray crystallography. In this work, the luminescent properties of 2, 4, 5, and 6 and the responsiveness of various chemical components contained in urine were investigated. These MOFs detect 1-naphthol (1-N), urinary thiodiglycolic acid (TDGA), uric acid (UA), and hippuric acid (HA), which are the final metabolites of carbaryl, vinyl chloride monomers, purine, and toluene, respectively. These new Ln-MOFs offer the potential for biomarkers or metabolic sensors and show excellent selective and sensitive luminescence detection of 1-N, TDGA, UA, and HA.

Graphical Abstract

Keywords:

• Ln-MOFs
• biomarkers
• metabolic sensors
• various urine chemicals
• luminescent property

Disclosure statement

No potential conflict of interest was reported by the authors.

Acknowledgements

This work was supported by the Fund of National Natural Science Foundation of China (Grant No. 21401151), Science and Technology Support Program of Sichuan Province (Grant No. 2015GZ0233), Science and Technology Huimin Program of Chengdu (Grant No. 2015-HM01-00336-SF), and the Innovative & Practice Project of Graduate School of Southwest Jiaotong University (Grant No. 2018CYPY07).

Correction Statement

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