Copper-cysteamine nanoparticles encapsulating fluorocoumarin silicon(IV) phthalocyanines: synthesis, characterization, and photophysical properties

Abstract

Three nanohybrid materials (FCSiPc@PEG-Cu-Cy) using poly (ethylene glycol) copper-cysteamine (PEG-Cu-Cy) nanoparticles as a carrier to load three fluorocoumarin silicon(IV) phthalocyanines (FCSiPcs) were prepared. The morphologies of these nanohybrids were characterized by transmission electron microscopy (TEM). The interactions between PEG-Cu-Cy nanoparticles and three FCSiPcs were studied by UV/Vis and fluorescence spectroscopic methods. The photophysical and photochemical properties of these FCSiPcs were influenced by PEG-Cu-Cy nanoparticles and exhibited substituents dependent of phthalocyanines in nanohybrids. The fluorescence resonance energy transfer (FRET) occurred from FCSiPcs (donors) to PEG-Cu-Cy nanoparticles (acceptors). These nanohybrids may be potential photosensitizers for photodynamic therapy.

Graphical Abstract

Keywords:

• Poly(ethylene glycol) copper-cysteamine
• fluorocoumarin
• phthalocyanine
• nanohybrid
• photophysical properties

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This research was supported by the National Key Basic Research Program of China (973 project) (2015CB352006), National Natural Science Foundation of China (21274021), Natural Science Foundation of Fujian (2019Y0007), The Science and Technology Fund project of Fujian province (No.2018Y9081), Scientific research innovation team construction programme of Fujian Normal University (IRTL 1702), and the Joint Funds of Fujian Provincial Health and Education Research (WKJ2019-23), The college students’ innovative and entrepreneurial training program of Fujian province (cxxl-2019179).